PTCT vs SPY

Comparison between PTC Therapeutics Inc (PTCT, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).

5-Year PerformanceSPY has outperformed PTCT, delivering a return of +13.9% compared to +12.9%

PTCT vs SPY - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	PTCT(COMPANY)	SPY(ETF)
Market Cap / Net Assets	$6.09B	$735B
Expense Ratio	N/A	0.09%
Max Drawdown	94.60%	56.47%
Sharpe Ratio	1.18	1.71
5Y Beta	1.06	1.00
Industry	Biotechnology	N/A
P/E Ratio	-31.82	28.81
Forward P/E	55.25	22.10
PEG Ratio	0.81	N/A
5Y Dividends CAGR	N/A	5.43%
5Y EPS CAGR	-16.59%	25.84%
Debt to Equity	-159.00%	34.16%
Free Cash Flow Yield	-3.72%	N/A
P/S Ratio	7.37	3.69
P/B Ratio	1743.27	5.54

Market Cap / Net Assets

PTCT

$6.09B

Winner

SPY

$735B

Expense Ratio

PTCT

N/A

SPY

0.09%

Max Drawdown

PTCT

94.60%

Winner

SPY

56.47%

Sharpe Ratio

PTCT

1.18

Winner

SPY

1.71

5Y Beta

PTCT

1.06

Winner

SPY

1.00

Industry

PTCT

Biotechnology

SPY

N/A

P/E Ratio

Winner

PTCT

-31.82

SPY

28.81

Forward P/E

PTCT

55.25

Winner

SPY

22.10

PEG Ratio

PTCT

0.81

SPY

N/A

5Y Dividends CAGR

PTCT

N/A

SPY

5.43%

5Y EPS CAGR

PTCT

-16.59%

Winner

SPY

25.84%

Debt to Equity

Winner

PTCT

-159.00%

SPY

34.16%

Free Cash Flow Yield

PTCT

-3.72%

SPY

N/A

P/S Ratio

PTCT

7.37

Winner

SPY

3.69

P/B Ratio

PTCT

1743.27

Winner

SPY

5.54

PTCT vs SPY - Historical Returns

Returns include dividend reinvestment.

Period	PTCT	SPY
1 month	-3.15%	+4.01%
3 months	+1.77%	+7.93%
6 months	-8.53%	+12.54%
1 year	+49.38%	+25.60%
5 years(CAGR)	+12.90%	+13.94%
10 years(CAGR)	+26.22%	+15.56%
Max(CAGR)	+11.87%	+8.49%

PTCT

-3.15%

Winner

SPY

+4.01%

PTCT

+1.77%

Winner

SPY

+7.93%

PTCT

-8.53%

Winner

SPY

+12.54%

Winner

PTCT

+49.38%

SPY

+25.60%

5Y(CAGR)

PTCT

+12.90%

Winner

SPY

+13.94%

10Y(CAGR)

Winner

PTCT

+26.22%

SPY

+15.56%

Max(CAGR)

Winner

PTCT

+11.87%

SPY

+8.49%

PTCT vs SPY - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	PTCT	SPY
2026	-8.59%	+8.42%
2025	+65.56%	+18.00%
2024	+60.98%	+25.59%
2023	-27.78%	+26.72%
2022	-10.36%	-18.64%
2021	-34.17%	+30.52%
2020	+25.99%	+17.28%
2019	+42.90%	+31.09%
2018	+96.56%	-5.24%
2017	+48.53%	+20.78%
2016	-64.65%	+13.59%
2015	-36.47%	+1.31%
2014	+209.26%	+14.56%
2013	+2.91%	+29.00%
2012	N/A	+14.17%
2011	N/A	+0.85%
2010	N/A	+13.14%
2009	N/A	+22.67%
2008	N/A	-36.25%
2007	N/A	+5.32%
2006	N/A	+13.85%
2005	N/A	+5.32%
2004	N/A	+10.75%
2003	N/A	+24.18%
2002	N/A	-22.42%
2001	N/A	-10.13%
2000	N/A	-8.84%
1999	N/A	+8.61%

PTCT vs SPY Drawdown Comparison

The maximum drawdown for PTCT was -94.60%, occurring on Nov 3, 2016. Recovery took 2689 trading sessions.

The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.

The current PTCT drawdown is -18.67%. The current SPY drawdown is -1.27%.

Rank	PTCT	SPY
#1	-94.60% Mar 17, 2015 - Nov 21, 2025	-55.20% Oct 9, 2007 - Aug 16, 2012
#2	-56.81% Feb 27, 2014 - Sep 15, 2014	-47.50% Mar 24, 2000 - Oct 26, 2006
#3	-39.55% Sep 23, 2013 - Jan 15, 2014	-33.70% Feb 19, 2020 - Aug 10, 2020
#4	-27.17% Nov 26, 2025 - Mar 6, 2026	-24.50% Jan 3, 2022 - Dec 13, 2023
#5	-25.36% Sep 26, 2014 - Dec 2, 2014	-19.34% Sep 20, 2018 - Apr 12, 2019
#6	-25.27% Jan 17, 2014 - Feb 20, 2014	-18.76% Feb 19, 2025 - Jun 26, 2025
#7	-23.59% Jul 18, 2013 - Sep 4, 2013	-13.02% Jul 20, 2015 - Apr 18, 2016
#8	-22.29% Jun 25, 2013 - Jul 17, 2013	-10.10% Jan 26, 2018 - Aug 6, 2018
#9	-19.59% Jan 20, 2015 - Feb 23, 2015	-9.44% Sep 2, 2020 - Nov 11, 2020
#10	-18.21% Sep 10, 2013 - Sep 23, 2013	-9.30% Jan 19, 2000 - Mar 17, 2000
#11	-13.33% Dec 12, 2014 - Dec 19, 2014	-9.05% Jul 19, 2007 - Oct 5, 2007
#12	-10.21% Dec 19, 2014 - Jan 13, 2015	-8.88% Jan 27, 2026 - Apr 14, 2026
#13	-6.13% Feb 25, 2015 - Mar 11, 2015	-8.41% Jul 16, 2024 - Sep 19, 2024
#14	-3.04% Dec 9, 2014 - Dec 11, 2014	-7.35% Sep 14, 2012 - Jan 2, 2013
#15	-2.36% Mar 12, 2015 - Mar 17, 2015	-7.27% Sep 18, 2014 - Oct 31, 2014