CIFR vs SYRE

Comparison between Cipher Mining Inc (CIFR, Company) and Spyre Therapeutics Inc (SYRE, Company).

CIFR is from the Technology sector, while SYRE is from the Healthcare sector.

5-Year PerformanceCIFR has outperformed SYRE, delivering a return of +14.9% compared to -10.2%

CIFR vs SYRE - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	CIFR(COMPANY)	SYRE(COMPANY)
Market Cap	$8.05B	$8.05B
Max Drawdown	97.16%	99.11%
Sharpe Ratio	1.60	2.92
5Y Beta	3.26	1.76
Industry	Information Technology Services	Biotechnology
P/E Ratio	-8.94	-41.36
Forward P/E	85.47	N/A
PEG Ratio	-0.02	N/A
5Y EPS CAGR	N/A	-2.15%
Debt to Equity	662.59%	0.00%
Free Cash Flow Yield	-13.49%	-2.31%

Market Cap

Winner

CIFR

$8.05B

SYRE

$8.05B

Max Drawdown

Winner

CIFR

97.16%

SYRE

99.11%

Sharpe Ratio

CIFR

1.60

Winner

SYRE

2.92

5Y Beta

CIFR

3.26

Winner

SYRE

1.76

Industry

CIFR

Information Technology Services

SYRE

Biotechnology

P/E Ratio

CIFR

-8.94

Winner

SYRE

-41.36

Forward P/E

CIFR

85.47

SYRE

N/A

PEG Ratio

CIFR

-0.02

SYRE

N/A

5Y EPS CAGR

CIFR

N/A

SYRE

-2.15%

Debt to Equity

CIFR

662.59%

Winner

SYRE

0.00%

Free Cash Flow Yield

CIFR

-13.49%

Winner

SYRE

-2.31%

CIFR vs SYRE - Historical Returns

Returns include dividend reinvestment.

Period	CIFR	SYRE
1 month	-23.67%	+22.12%
3 months	+10.39%	+47.95%
6 months	+13.41%	+208.46%
1 year	+232.83%	+566.69%
5 years(CAGR)	+14.88%	-10.25%
10 years(CAGR)	N/A	-1.01%
Max(CAGR)	+13.45%	-8.15%

CIFR

-23.67%

Winner

SYRE

+22.12%

CIFR

+10.39%

Winner

SYRE

+47.95%

CIFR

+13.41%

Winner

SYRE

+208.46%

CIFR

+232.83%

Winner

SYRE

+566.69%

5Y(CAGR)

Winner

CIFR

+14.88%

SYRE

-10.25%

10Y(CAGR)

CIFR

N/A

SYRE

-1.01%

Max(CAGR)

Winner

CIFR

+13.45%

SYRE

-8.15%

CIFR vs SYRE - Annual Returns (2016 - 2026)

Returns include dividend reinvestment.

Year	CIFR	SYRE
2026	+22.65%	+233.78%
2025	+205.59%	+37.36%
2024	+12.35%	+8.79%
2023	+545.62%	+104.27%
2022	-87.85%	-90.57%
2021	-53.61%	-44.51%
2020	+1.53%	+1.55%
2019	N/A	-4.98%
2018	N/A	+39.22%
2017	N/A	+18.38%
2016	N/A	-55.48%

CIFR vs SYRE Drawdown Comparison

The maximum drawdown for CIFR was -97.16%, occurring on Dec 28, 2022. Recovery took 1016 trading sessions.

The maximum drawdown for SYRE was -99.11%, occurring on Jun 21, 2023. This drawdown has not yet recovered.

The current CIFR drawdown is -31.91%. The current SYRE drawdown is -65.95%.

Rank	CIFR	SYRE
#1	-97.16% Sep 16, 2021 - Oct 3, 2025	-99.11% Apr 8, 2016 - Jun 21, 2023
#2	-51.38% Nov 5, 2025 - May 27, 2026	N/A
#3	-31.91% Jun 18, 2026 - Jul 14, 2026	N/A
#4	-23.40% Oct 15, 2025 - Nov 3, 2025	N/A
#5	-21.54% Mar 11, 2021 - Sep 9, 2021	N/A
#6	-20.05% Jun 2, 2026 - Jun 17, 2026	N/A
#7	-6.00% May 27, 2026 - Jun 2, 2026	N/A
#8	-5.67% Oct 9, 2025 - Oct 13, 2025	N/A
#9	-5.50% Sep 13, 2021 - Sep 16, 2021	N/A
#10	-4.21% Feb 19, 2021 - Mar 5, 2021	N/A
#11	-1.63% Jan 25, 2021 - Feb 19, 2021	N/A
#12	-1.13% Mar 9, 2021 - Mar 11, 2021	N/A
#13	-1.10% Nov 3, 2025 - Nov 5, 2025	N/A
#14	-1.08% Mar 5, 2021 - Mar 9, 2021	N/A
#15	-0.50% Dec 28, 2020 - Jan 6, 2021	N/A