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CBOE vs ALNY

Comparison between Cboe Global Markets Inc (CBOE, Company) and Alnylam Pharmaceuticals Inc (ALNY, Company).

CBOE is from the Financial Services sector, while ALNY is from the Healthcare sector.

5-Year PerformanceCBOE has outperformed ALNY, delivering a return of +18.7% compared to +4.3%

CBOE vs ALNY - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap
Winner
CBOE
$30B
ALNY
$30B
Max Drawdown
Winner
CBOE
44.70%
ALNY
83.58%
Sharpe Ratio
Winner
CBOE
0.49
ALNY
-1.21
5Y Beta
CBOE
-0.23
ALNY
N/A
Industry
CBOE
Financial Data & Stock Exchanges
ALNY
Biotechnology
P/E Ratio
Winner
CBOE
22.50
ALNY
59.87
Forward P/E
Winner
CBOE
23.09
ALNY
26.32
PEG Ratio
CBOE
0.45
Winner
ALNY
0.41
Dividend Yield
CBOE
0.98%
ALNY
N/A
5Y Dividends CAGR
CBOE
15.88%
ALNY
N/A
5Y EPS CAGR
CBOE
25.82%
ALNY
N/A
Debt to Equity
CBOE
25.66%
Winner
ALNY
0.00%
Free Cash Flow Yield
Winner
CBOE
6.21%
ALNY
3.12%
P/S Ratio
Winner
CBOE
6.11
ALNY
6.37
P/B Ratio
Winner
CBOE
5.50
ALNY
21.44

CBOE vs ALNY - Historical Returns

Returns include dividend reinvestment.

1M
Winner
CBOE
+0.91%
ALNY
-11.02%
3M
CBOE
-22.49%
Winner
ALNY
-17.56%
6M
Winner
CBOE
-1.45%
ALNY
-28.51%
1Y
Winner
CBOE
+15.26%
ALNY
-47.06%
5Y(CAGR)
Winner
CBOE
+18.65%
ALNY
+4.25%
10Y(CAGR)
Winner
CBOE
+16.73%
ALNY
+12.80%
Max(CAGR)
CBOE
+16.13%
Winner
ALNY
+17.30%

CBOE vs ALNY - Annual Returns (2004 - 2026)

Returns include dividend reinvestment.

YearCBOEALNY
2026+13.67%-39.37%
2025+29.26%+70.21%
2024+10.97%+20.72%
2023+43.39%-18.06%
2022-0.69%+36.65%
2021+43.01%+32.38%
2020-20.85%+12.41%
2019+26.67%+58.29%
2018-19.41%-44.70%
2017+72.52%+228.80%
2016+17.16%-59.75%
2015+3.86%-3.71%
2014+26.20%+51.89%
2013+76.75%+235.42%
2012+18.60%+110.74%
2011+10.73%-18.58%
2010-29.02%-45.64%
2009N/A-29.94%
2008N/A-14.49%
2007N/A+34.82%
2006N/A+65.12%
2005N/A+76.25%
2004N/A+6.71%

CBOE vs ALNY Drawdown Comparison

The maximum drawdown for CBOE was -43.22%, occurring on Mar 18, 2020. Recovery took 945 trading sessions.

The maximum drawdown for ALNY was -83.58%, occurring on Oct 3, 2011. Recovery took 1443 trading sessions.

The current CBOE drawdown is -23.27%. The current ALNY drawdown is -50.61%.

RankCBOEALNY
#1-43.22%
Jan 25, 2018 - Oct 26, 2021
-83.58%
Oct 9, 2007 - Jul 3, 2013
#2-39.39%
Jun 23, 2010 - Jan 4, 2013
-77.36%
Jun 22, 2015 - Nov 10, 2017
#3-36.73%
May 13, 2026 - Jun 29, 2026
-58.17%
Oct 20, 2025 - Jul 30, 2026
#4-21.78%
Nov 2, 2021 - Mar 29, 2023
-57.81%
Mar 20, 2018 - Jun 19, 2020
#5-19.93%
Mar 17, 2014 - Oct 29, 2014
-52.18%
Jun 9, 2004 - Jan 6, 2005
#6-17.11%
Jan 7, 2015 - Sep 30, 2015
-47.61%
Jan 13, 2014 - Oct 24, 2014
#7-17.03%
Nov 27, 2015 - Dec 2, 2016
-42.46%
Oct 14, 2021 - Aug 3, 2022
#8-14.48%
Feb 23, 2024 - Aug 5, 2024
-40.61%
Dec 21, 2022 - Jun 26, 2024
#9-12.14%
Nov 27, 2024 - Mar 10, 2025
-36.52%
Mar 29, 2006 - Oct 31, 2006
#10-11.11%
Aug 2, 2013 - Oct 23, 2013
-36.33%
Dec 8, 2006 - Jul 11, 2007
#11-10.32%
Mar 3, 2026 - Apr 15, 2026
-34.67%
Sep 12, 2005 - Jan 10, 2006
#12-9.95%
Nov 22, 2013 - Feb 10, 2014
-32.55%
Jan 10, 2005 - Sep 7, 2005
#13-9.05%
Mar 31, 2025 - May 2, 2025
-26.79%
Jan 25, 2021 - Jun 18, 2021
#14-8.84%
May 7, 2025 - Jul 7, 2025
-26.77%
Jul 20, 2020 - Jan 12, 2021
#15-8.43%
Oct 24, 2024 - Nov 26, 2024
-25.36%
Oct 16, 2024 - May 30, 2025

Correlation

Correlation between CBOE and ALNY is 0.91 which considered as a very strong positive correlation - the stocks move almost identically together.

0.91
-101

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