ALNY vs LPLA

Comparison between Alnylam Pharmaceuticals Inc (ALNY, Company) and LPL Financial Holdings Inc (LPLA, Company).

ALNY is from the Healthcare sector, while LPLA is from the Financial Services sector.

5-Year PerformanceLPLA has outperformed ALNY, delivering a return of +21.4% compared to +4.3%

ALNY vs LPLA - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	ALNY(COMPANY)	LPLA(COMPANY)
Market Cap	$30B	$30B
Max Drawdown	83.58%	70.50%
Sharpe Ratio	-1.21	0.12
5Y Beta	N/A	1.09
Industry	Biotechnology	Capital Markets
P/E Ratio	59.87	30.75
Forward P/E	26.32	13.83
PEG Ratio	0.41	0.50
Dividend Yield	N/A	0.33%
5Y Dividends CAGR	N/A	8.45%
5Y EPS CAGR	N/A	13.77%
Debt to Equity	0.00%	129.59%
Free Cash Flow Yield	3.12%	-3.10%
P/S Ratio	6.37	1.52
P/B Ratio	21.44	5.09

Market Cap

ALNY

$30B

Winner

LPLA

$30B

Max Drawdown

ALNY

83.58%

Winner

LPLA

70.50%

Sharpe Ratio

ALNY

-1.21

Winner

LPLA

0.12

5Y Beta

ALNY

N/A

LPLA

1.09

Industry

ALNY

Biotechnology

LPLA

Capital Markets

P/E Ratio

ALNY

59.87

Winner

LPLA

30.75

Forward P/E

ALNY

26.32

Winner

LPLA

13.83

PEG Ratio

Winner

ALNY

0.41

LPLA

0.50

Dividend Yield

ALNY

N/A

LPLA

0.33%

5Y Dividends CAGR

ALNY

N/A

LPLA

8.45%

5Y EPS CAGR

ALNY

N/A

LPLA

13.77%

Debt to Equity

Winner

ALNY

0.00%

LPLA

129.59%

Free Cash Flow Yield

Winner

ALNY

3.12%

LPLA

-3.10%

P/S Ratio

ALNY

6.37

Winner

LPLA

1.52

P/B Ratio

ALNY

21.44

Winner

LPLA

5.09

ALNY vs LPLA - Historical Returns

Returns include dividend reinvestment.

Period	ALNY	LPLA
1 month	-11.02%	+9.62%
3 months	-17.56%	+25.24%
6 months	-28.51%	+9.86%
1 year	-47.06%	+2.63%
5 years(CAGR)	+4.25%	+21.39%
10 years(CAGR)	+12.80%	+30.20%
Max(CAGR)	+17.30%	+18.50%

ALNY

-11.02%

Winner

LPLA

+9.62%

ALNY

-17.56%

Winner

LPLA

+25.24%

ALNY

-28.51%

Winner

LPLA

+9.86%

ALNY

-47.06%

Winner

LPLA

+2.63%

5Y(CAGR)

ALNY

+4.25%

Winner

LPLA

+21.39%

10Y(CAGR)

ALNY

+12.80%

Winner

LPLA

+30.20%

Max(CAGR)

ALNY

+17.30%

Winner

LPLA

+18.50%

ALNY vs LPLA - Annual Returns (2004 - 2026)

Returns include dividend reinvestment.

Year	ALNY	LPLA
2026	-39.37%	-0.38%
2025	+70.21%	+9.26%
2024	+20.72%	+42.17%
2023	-18.06%	+5.39%
2022	+36.65%	+33.43%
2021	+32.38%	+55.94%
2020	+12.41%	+12.56%
2019	+58.29%	+51.80%
2018	-44.70%	+8.40%
2017	+228.80%	+64.14%
2016	-59.75%	-13.85%
2015	-3.71%	-2.51%
2014	+51.89%	-3.43%
2013	+235.42%	+65.69%
2012	+110.74%	-2.00%
2011	-18.58%	-12.66%
2010	-45.64%	+13.13%
2009	-29.94%	N/A
2008	-14.49%	N/A
2007	+34.82%	N/A
2006	+65.12%	N/A
2005	+76.25%	N/A
2004	+6.71%	N/A

ALNY vs LPLA Drawdown Comparison

The maximum drawdown for ALNY was -83.58%, occurring on Oct 3, 2011. Recovery took 1443 trading sessions.

The maximum drawdown for LPLA was -69.32%, occurring on Feb 12, 2016. Recovery took 888 trading sessions.

The current ALNY drawdown is -50.61%. The current LPLA drawdown is -9.56%.

Rank	ALNY	LPLA
#1	-83.58% Oct 9, 2007 - Jul 3, 2013	-69.32% Mar 20, 2014 - Sep 27, 2017
#2	-77.36% Jun 22, 2015 - Nov 10, 2017	-60.33% Jan 16, 2020 - Dec 3, 2020
#3	-58.17% Oct 20, 2025 - Jul 30, 2026	-33.78% May 2, 2011 - Mar 15, 2012
#4	-57.81% Mar 20, 2018 - Jun 19, 2020	-33.18% Jun 20, 2024 - Nov 6, 2024
#5	-52.18% Jun 9, 2004 - Jan 6, 2005	-33.12% Jul 30, 2025 - May 28, 2026
#6	-47.61% Jan 13, 2014 - Oct 24, 2014	-32.61% Nov 8, 2022 - Feb 26, 2024
#7	-42.46% Oct 14, 2021 - Aug 3, 2022	-30.11% Apr 3, 2012 - May 9, 2013
#8	-40.61% Dec 21, 2022 - Jun 26, 2024	-26.06% May 22, 2018 - Feb 1, 2019
#9	-36.52% Mar 29, 2006 - Oct 31, 2006	-26.02% Feb 19, 2025 - May 13, 2025
#10	-36.33% Dec 8, 2006 - Jul 11, 2007	-24.69% Feb 9, 2022 - Apr 8, 2022
#11	-34.67% Sep 12, 2005 - Jan 10, 2006	-23.36% Apr 19, 2022 - Aug 4, 2022
#12	-32.55% Jan 10, 2005 - Sep 7, 2005	-18.87% Jul 24, 2019 - Nov 7, 2019
#13	-26.79% Jan 25, 2021 - Jun 18, 2021	-18.45% Apr 30, 2021 - Sep 27, 2021
#14	-26.77% Jul 20, 2020 - Jan 12, 2021	-14.36% Mar 16, 2018 - May 8, 2018
#15	-25.36% Oct 16, 2024 - May 30, 2025	-12.71% Feb 19, 2019 - May 3, 2019