ALNY vs AEE

Comparison between Alnylam Pharmaceuticals Inc (ALNY, Company) and Ameren Corp (AEE, Company).

ALNY is from the Healthcare sector, while AEE is from the Utilities sector.

5-Year PerformanceAEE has outperformed ALNY, delivering a return of +7.2% compared to +4.3%

ALNY vs AEE - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	ALNY(COMPANY)	AEE(COMPANY)
Market Cap	$30B	$30B
Max Drawdown	83.58%	64.90%
Sharpe Ratio	-1.21	0.55
5Y Beta	N/A	0.12
Industry	Biotechnology	Utilities - Regulated Electric
P/E Ratio	59.87	19.02
Forward P/E	26.32	20.37
PEG Ratio	0.41	0.76
Dividend Yield	N/A	2.67%
5Y Dividends CAGR	N/A	6.86%
5Y EPS CAGR	N/A	9.23%
Debt to Equity	0.00%	150.42%
Free Cash Flow Yield	3.12%	-4.65%
P/S Ratio	6.37	3.59
P/B Ratio	21.44	2.16

Market Cap

ALNY

$30B

Winner

AEE

$30B

Max Drawdown

ALNY

83.58%

Winner

AEE

64.90%

Sharpe Ratio

ALNY

-1.21

Winner

AEE

0.55

5Y Beta

ALNY

N/A

AEE

0.12

Industry

ALNY

Biotechnology

AEE

Utilities - Regulated Electric

P/E Ratio

ALNY

59.87

Winner

AEE

19.02

Forward P/E

ALNY

26.32

Winner

AEE

20.37

PEG Ratio

Winner

ALNY

0.41

AEE

0.76

Dividend Yield

ALNY

N/A

AEE

2.67%

5Y Dividends CAGR

ALNY

N/A

AEE

6.86%

5Y EPS CAGR

ALNY

N/A

AEE

9.23%

Debt to Equity

Winner

ALNY

0.00%

AEE

150.42%

Free Cash Flow Yield

Winner

ALNY

3.12%

AEE

-4.65%

P/S Ratio

ALNY

6.37

Winner

AEE

3.59

P/B Ratio

ALNY

21.44

Winner

AEE

2.16

ALNY vs AEE - Historical Returns

Returns include dividend reinvestment.

Period	ALNY	AEE
1 month	-11.02%	-1.03%
3 months	-17.56%	+0.95%
6 months	-28.51%	+0.90%
1 year	-47.06%	+10.33%
5 years(CAGR)	+4.25%	+7.16%
10 years(CAGR)	+12.80%	+11.19%
Max(CAGR)	+17.30%	+8.80%

ALNY

-11.02%

Winner

AEE

-1.03%

ALNY

-17.56%

Winner

AEE

+0.95%

ALNY

-28.51%

Winner

AEE

+0.90%

ALNY

-47.06%

Winner

AEE

+10.33%

5Y(CAGR)

ALNY

+4.25%

Winner

AEE

+7.16%

10Y(CAGR)

Winner

ALNY

+12.80%

AEE

+11.19%

Max(CAGR)

Winner

ALNY

+17.30%

AEE

+8.80%

ALNY vs AEE - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	ALNY	AEE
2026	-39.37%	+9.84%
2025	+70.21%	+15.51%
2024	+20.72%	+24.64%
2023	-18.06%	-15.67%
2022	+36.65%	+3.04%
2021	+32.38%	+20.06%
2020	+12.41%	+5.30%
2019	+58.29%	+24.05%
2018	-44.70%	+15.15%
2017	+228.80%	+16.14%
2016	-59.75%	+27.38%
2015	-3.71%	-2.07%
2014	+51.89%	+35.08%
2013	+235.42%	+20.95%
2012	+110.74%	-1.43%
2011	-18.58%	+23.66%
2010	-45.64%	+7.60%
2009	-29.94%	-12.66%
2008	-14.49%	-33.53%
2007	+34.82%	+5.41%
2006	+65.12%	+8.82%
2005	+76.25%	+9.20%
2004	+6.71%	+15.59%
2003	N/A	+15.44%
2002	N/A	+3.31%
2001	N/A	-0.52%
2000	N/A	+53.67%
1999	N/A	-11.92%

ALNY vs AEE Drawdown Comparison

The maximum drawdown for ALNY was -83.58%, occurring on Oct 3, 2011. Recovery took 1443 trading sessions.

The maximum drawdown for AEE was -60.56%, occurring on Mar 9, 2009. Recovery took 1550 trading sessions.

The current ALNY drawdown is -50.61%. The current AEE drawdown is -7.64%.

Rank	ALNY	AEE
#1	-83.58% Oct 9, 2007 - Jul 3, 2013	-60.56% Dec 24, 2007 - Feb 21, 2014
#2	-77.36% Jun 22, 2015 - Nov 10, 2017	-29.09% Mar 4, 2020 - Apr 20, 2021
#3	-58.17% Oct 20, 2025 - Jul 30, 2026	-27.48% Apr 20, 2022 - Nov 11, 2024
#4	-57.81% Mar 20, 2018 - Jun 19, 2020	-24.54% Nov 2, 1999 - Apr 25, 2000
#5	-52.18% Jun 9, 2004 - Jan 6, 2005	-20.09% Dec 29, 2014 - Feb 2, 2016
#6	-47.61% Jan 13, 2014 - Oct 24, 2014	-17.91% Nov 14, 2017 - Aug 14, 2018
#7	-42.46% Oct 14, 2021 - Aug 3, 2022	-17.76% May 23, 2002 - Aug 12, 2002
#8	-40.61% Dec 21, 2022 - Jun 26, 2024	-17.57% Dec 26, 2000 - May 14, 2002
#9	-36.52% Mar 29, 2006 - Oct 31, 2006	-15.08% Jan 6, 2003 - May 23, 2003
#10	-36.33% Dec 8, 2006 - Jul 11, 2007	-14.42% Jan 30, 2004 - Sep 16, 2004
#11	-34.67% Sep 12, 2005 - Jan 10, 2006	-12.57% Aug 12, 2002 - Jan 6, 2003
#12	-32.55% Jan 10, 2005 - Sep 7, 2005	-12.50% Sep 16, 2005 - Oct 18, 2006
#13	-26.79% Jan 25, 2021 - Jun 18, 2021	-12.39% May 16, 2007 - Oct 4, 2007
#14	-26.77% Jul 20, 2020 - Jan 12, 2021	-12.33% Sep 12, 2000 - Nov 29, 2000
#15	-25.36% Oct 16, 2024 - May 30, 2025	-12.07% Jul 6, 2016 - Jan 6, 2017