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AXSM vs SPY

Comparison between Axsome Therapeutics Inc (AXSM, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).

5-Year PerformanceAXSM has outperformed SPY, delivering a return of +32.7% compared to +13.2%

AXSM vs SPY - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap / Net Assets
AXSM
$11B
Winner
SPY
$781B
Expense Ratio
AXSM
N/A
SPY
0.09%
Max Drawdown
AXSM
86.65%
Winner
SPY
56.47%
Sharpe Ratio
Winner
AXSM
1.77
SPY
1.43
5Y Beta
Winner
AXSM
0.65
SPY
1.00
Industry
AXSM
Biotechnology
SPY
N/A
P/E Ratio
Winner
AXSM
-57.24
SPY
26.48
Forward P/E
AXSM
333.33
Winner
SPY
20.89
PEG Ratio
Winner
AXSM
0.00
SPY
0.30
5Y Dividends CAGR
AXSM
N/A
SPY
6.00%
5Y EPS CAGR
AXSM
6.89%
Winner
SPY
26.40%
Debt to Equity
AXSM
344.13%
Winner
SPY
48.17%
Free Cash Flow Yield
AXSM
-0.65%
SPY
N/A
P/S Ratio
AXSM
15.47
Winner
SPY
3.72
P/B Ratio
AXSM
205.50
Winner
SPY
5.55

AXSM vs SPY - Historical Returns

Returns include dividend reinvestment.

1M
AXSM
-13.38%
Winner
SPY
+2.30%
3M
AXSM
-5.61%
Winner
SPY
+5.00%
6M
Winner
AXSM
+15.11%
SPY
+11.88%
1Y
Winner
AXSM
+103.50%
SPY
+22.80%
5Y(CAGR)
Winner
AXSM
+32.66%
SPY
+13.20%
10Y(CAGR)
Winner
AXSM
+39.20%
SPY
+15.26%
Max(CAGR)
Winner
AXSM
+34.56%
SPY
+8.59%

AXSM vs SPY - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

YearAXSMSPY
2026+17.59%+13.10%
2025+109.16%+18.00%
2024+9.80%+25.59%
2023+8.55%+26.72%
2022+103.89%-18.64%
2021-53.61%+30.52%
2020-19.58%+17.28%
2019+3756.72%+31.09%
2018-48.49%-5.24%
2017-13.18%+20.78%
2016-44.63%+13.59%
2015+6.06%+1.31%
2014N/A+14.56%
2013N/A+29.00%
2012N/A+14.17%
2011N/A+0.85%
2010N/A+13.14%
2009N/A+22.67%
2008N/A-36.25%
2007N/A+5.32%
2006N/A+13.85%
2005N/A+5.32%
2004N/A+10.75%
2003N/A+24.18%
2002N/A-22.42%
2001N/A-10.13%
2000N/A-8.84%
1999N/A+8.61%

AXSM vs SPY Drawdown Comparison

The maximum drawdown for AXSM was -86.65%, occurring on Dec 27, 2018. Recovery took 809 trading sessions.

The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.

The current AXSM drawdown is -17.65%. The current SPY drawdown is -0.36%.

RankAXSMSPY
#1-86.65%
Jan 5, 2016 - Mar 25, 2019		-55.20%
Oct 9, 2007 - Aug 16, 2012
#2-81.26%
Dec 26, 2019 - Jan 30, 2025		-47.50%
Mar 24, 2000 - Oct 26, 2006
#3-42.70%
Sep 16, 2019 - Nov 19, 2019		-33.70%
Feb 19, 2020 - Aug 10, 2020
#4-30.56%
Feb 21, 2025 - Nov 6, 2025		-24.50%
Jan 3, 2022 - Dec 13, 2023
#5-18.50%
Jan 21, 2026 - Apr 30, 2026		-19.34%
Sep 20, 2018 - Apr 12, 2019
#6-17.65%
Jun 12, 2026 - Aug 6, 2026		-18.76%
Feb 19, 2025 - Jun 26, 2025
#7-17.63%
Mar 25, 2019 - Apr 25, 2019		-13.02%
Jul 20, 2015 - Apr 18, 2016
#8-17.48%
Jul 26, 2019 - Sep 16, 2019		-10.10%
Jan 26, 2018 - Aug 6, 2018
#9-17.26%
May 28, 2019 - Jun 20, 2019		-9.44%
Sep 2, 2020 - Nov 11, 2020
#10-11.38%
Jun 20, 2019 - Jun 27, 2019		-9.30%
Jan 19, 2000 - Mar 17, 2000
#11-10.33%
Nov 24, 2015 - Dec 29, 2015		-9.05%
Jul 19, 2007 - Oct 5, 2007
#12-9.37%
Jul 2, 2019 - Jul 26, 2019		-8.88%
Jan 27, 2026 - Apr 14, 2026
#13-8.83%
Dec 4, 2019 - Dec 10, 2019		-8.41%
Jul 16, 2024 - Sep 19, 2024
#14-8.26%
Dec 31, 2025 - Jan 20, 2026		-7.35%
Sep 14, 2012 - Jan 2, 2013
#15-7.23%
Feb 5, 2025 - Feb 10, 2025		-7.27%
Sep 18, 2014 - Oct 31, 2014

Correlation

Correlation between AXSM and SPY is 0.89 which considered as a strong positive correlation - the stocks tend to move together.

0.89
-101

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