AXSM vs GMED

Comparison between Axsome Therapeutics Inc (AXSM, Company) and Globus Medical Inc - Class A (GMED, Company).

Both AXSM and GMED are from the Healthcare sector.

5-Year PerformanceAXSM has outperformed GMED, delivering a return of +33.0% compared to +0.5%

AXSM vs GMED - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	AXSM(COMPANY)	GMED(COMPANY)
Market Cap	$11B	$11B
Max Drawdown	86.65%	47.91%
Sharpe Ratio	1.81	1.04
5Y Beta	0.65	0.89
Industry	Biotechnology	Medical Devices
P/E Ratio	-57.24	20.89
Forward P/E	333.33	17.36
PEG Ratio	0.00	0.04
5Y EPS CAGR	6.89%	21.12%
Debt to Equity	344.13%	0.00%
Free Cash Flow Yield	-0.65%	5.60%
P/S Ratio	15.47	3.53
P/B Ratio	205.50	2.26

Market Cap

Winner

AXSM

$11B

GMED

$11B

Max Drawdown

AXSM

86.65%

Winner

GMED

47.91%

Sharpe Ratio

Winner

AXSM

1.81

GMED

1.04

5Y Beta

Winner

AXSM

0.65

GMED

0.89

Industry

AXSM

Biotechnology

GMED

Medical Devices

P/E Ratio

Winner

AXSM

-57.24

GMED

20.89

Forward P/E

AXSM

333.33

Winner

GMED

17.36

PEG Ratio

Winner

AXSM

0.00

GMED

0.04

5Y EPS CAGR

AXSM

6.89%

Winner

GMED

21.12%

Debt to Equity

AXSM

344.13%

Winner

GMED

0.00%

Free Cash Flow Yield

AXSM

-0.65%

Winner

GMED

5.60%

P/S Ratio

AXSM

15.47

Winner

GMED

3.53

P/B Ratio

AXSM

205.50

Winner

GMED

2.26

AXSM vs GMED - Historical Returns

Returns include dividend reinvestment.

Period	AXSM	GMED
1 month	-14.82%	+4.45%
3 months	-3.40%	-3.21%
6 months	+16.54%	-6.23%
1 year	+103.93%	+52.28%
5 years(CAGR)	+32.96%	+0.46%
10 years(CAGR)	+39.38%	+13.50%
Max(CAGR)	+34.70%	+13.78%

AXSM

-14.82%

Winner

GMED

+4.45%

AXSM

-3.40%

Winner

GMED

-3.21%

Winner

AXSM

+16.54%

GMED

-6.23%

Winner

AXSM

+103.93%

GMED

+52.28%

5Y(CAGR)

Winner

AXSM

+32.96%

GMED

+0.46%

10Y(CAGR)

Winner

AXSM

+39.38%

GMED

+13.50%

Max(CAGR)

Winner

AXSM

+34.70%

GMED

+13.78%

AXSM vs GMED - Annual Returns (2012 - 2026)

Returns include dividend reinvestment.

Year	AXSM	GMED
2026	+19.06%	-5.68%
2025	+109.16%	+6.70%
2024	+9.80%	+55.59%
2023	+8.55%	-27.16%
2022	+103.89%	+0.45%
2021	-53.61%	+13.99%
2020	-19.58%	+9.71%
2019	+3756.72%	+48.65%
2018	-48.49%	+0.25%
2017	-13.18%	+65.79%
2016	-44.63%	-7.11%
2015	+6.06%	+17.28%
2014	N/A	+20.35%
2013	N/A	+84.46%
2012	N/A	-22.30%

AXSM vs GMED Drawdown Comparison

The maximum drawdown for AXSM was -86.65%, occurring on Dec 27, 2018. Recovery took 809 trading sessions.

The maximum drawdown for GMED was -47.91%, occurring on Nov 13, 2023. Recovery took 807 trading sessions.

The current AXSM drawdown is -16.63%. The current GMED drawdown is -14.96%.

Rank	AXSM	GMED
#1	-86.65% Jan 5, 2016 - Mar 25, 2019	-47.91% Sep 8, 2021 - Nov 21, 2024
#2	-81.26% Dec 26, 2019 - Jan 30, 2025	-44.69% Oct 2, 2012 - Oct 31, 2013
#3	-42.70% Sep 16, 2019 - Nov 19, 2019	-44.40% Jan 22, 2025 - Jan 8, 2026
#4	-30.56% Feb 21, 2025 - Nov 6, 2025	-41.08% Dec 19, 2019 - Nov 24, 2020
#5	-18.50% Jan 21, 2026 - Apr 30, 2026	-33.70% Nov 8, 2018 - Dec 12, 2019
#6	-17.65% Jun 12, 2026 - Aug 6, 2026	-32.69% Apr 2, 2014 - Jul 21, 2015
#7	-17.63% Mar 25, 2019 - Apr 25, 2019	-26.88% Dec 30, 2015 - Feb 24, 2017
#8	-17.48% Jul 26, 2019 - Sep 16, 2019	-26.37% Jul 31, 2015 - Dec 29, 2015
#9	-17.26% May 28, 2019 - Jun 20, 2019	-22.10% Apr 20, 2026 - Jun 17, 2026
#10	-11.38% Jun 20, 2019 - Jun 27, 2019	-16.70% Jun 23, 2017 - Nov 9, 2017
#11	-10.33% Nov 24, 2015 - Dec 29, 2015	-14.11% Jun 6, 2018 - Nov 8, 2018
#12	-9.37% Jul 2, 2019 - Jul 26, 2019	-13.65% Feb 26, 2026 - Apr 20, 2026
#13	-8.83% Dec 4, 2019 - Dec 10, 2019	-11.35% Feb 12, 2021 - Apr 14, 2021
#14	-8.26% Dec 31, 2025 - Jan 20, 2026	-8.77% Jan 8, 2021 - Feb 12, 2021
#15	-7.23% Feb 5, 2025 - Feb 10, 2025	-8.59% Jul 27, 2021 - Sep 2, 2021