AXSM vs MANH

Comparison between Axsome Therapeutics Inc (AXSM, Company) and Manhattan Associates Inc (MANH, Company).

AXSM is from the Healthcare sector, while MANH is from the Technology sector.

5-Year PerformanceAXSM has outperformed MANH, delivering a return of +56.4% compared to +5.0%

AXSM vs MANH - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	AXSM(COMPANY)	MANH(COMPANY)
Market Cap	$11B	$11B
Max Drawdown	86.65%	84.66%
Sharpe Ratio	1.80	0.01
5Y Beta	0.65	1.08
Industry	Biotechnology	Software - Application
P/E Ratio	-57.45	54.45
Forward P/E	333.33	37.04
5Y EPS CAGR	4.27%	17.87%
Debt to Equity	225.63%	0.00%
Free Cash Flow Yield	-0.64%	3.55%

Market Cap

AXSM

$11B

Winner

MANH

$11B

Max Drawdown

AXSM

86.65%

Winner

MANH

84.66%

Sharpe Ratio

Winner

AXSM

1.80

MANH

0.01

5Y Beta

Winner

AXSM

0.65

MANH

1.08

Industry

AXSM

Biotechnology

MANH

Software - Application

P/E Ratio

Winner

AXSM

-57.45

MANH

54.45

Forward P/E

AXSM

333.33

Winner

MANH

37.04

5Y EPS CAGR

AXSM

4.27%

Winner

MANH

17.87%

Debt to Equity

AXSM

225.63%

Winner

MANH

0.00%

Free Cash Flow Yield

AXSM

-0.64%

Winner

MANH

3.55%

AXSM vs MANH - Historical Returns

Returns include dividend reinvestment.

Period	AXSM	MANH
1 month	-6.40%	+26.92%
3 months	-9.20%	+60.02%
6 months	+17.92%	+43.05%
1 year	+95.34%	-8.75%
5 years(CAGR)	+56.37%	+5.03%
10 years(CAGR)	+39.89%	+12.98%
Max(CAGR)	+34.70%	+20.67%

AXSM

-6.40%

Winner

MANH

+26.92%

AXSM

-9.20%

Winner

MANH

+60.02%

AXSM

+17.92%

Winner

MANH

+43.05%

Winner

AXSM

+95.34%

MANH

-8.75%

5Y(CAGR)

Winner

AXSM

+56.37%

MANH

+5.03%

10Y(CAGR)

Winner

AXSM

+39.89%

MANH

+12.98%

Max(CAGR)

Winner

AXSM

+34.70%

MANH

+20.67%

AXSM vs MANH - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	AXSM	MANH
2026	+19.58%	+20.11%
2025	+109.16%	-35.53%
2024	+9.80%	+30.70%
2023	+8.55%	+77.95%
2022	+103.89%	-20.46%
2021	-53.61%	+50.55%
2020	-19.58%	+30.37%
2019	+3756.72%	+89.03%
2018	-48.49%	-15.70%
2017	-13.18%	-9.35%
2016	-44.63%	-17.99%
2015	+6.06%	+66.59%
2014	N/A	+38.53%
2013	N/A	+86.39%
2012	N/A	+49.43%
2011	N/A	+30.75%
2010	N/A	+23.10%
2009	N/A	+50.16%
2008	N/A	-38.60%
2007	N/A	-12.60%
2006	N/A	+41.89%
2005	N/A	-14.74%
2004	N/A	-12.53%
2003	N/A	+18.02%
2002	N/A	-18.41%
2001	N/A	-12.99%
2000	N/A	+454.50%
1999	N/A	+40.48%

AXSM vs MANH Drawdown Comparison

The maximum drawdown for AXSM was -86.65%, occurring on Dec 27, 2018. Recovery took 809 trading sessions.

The maximum drawdown for MANH was -84.66%, occurring on Apr 3, 2001. Recovery took 3103 trading sessions.

The current AXSM drawdown is -16.26%. The current MANH drawdown is -35.14%.

Rank	AXSM	MANH
#1	-86.65% Jan 5, 2016 - Mar 25, 2019	-84.66% Oct 26, 2000 - Mar 4, 2013
#2	-81.26% Dec 26, 2019 - Jan 30, 2025	-60.98% Dec 12, 2024 - Apr 10, 2026
#3	-42.70% Sep 16, 2019 - Nov 19, 2019	-57.93% Feb 4, 2020 - May 27, 2020
#4	-30.56% Feb 21, 2025 - Nov 6, 2025	-48.04% Dec 4, 2015 - Jul 24, 2019
#5	-18.50% Jan 21, 2026 - Apr 30, 2026	-45.26% Mar 31, 2000 - Jul 14, 2000
#6	-17.65% Jun 12, 2026 - Aug 6, 2026	-41.38% Nov 2, 2021 - Jun 2, 2023
#7	-17.63% Mar 25, 2019 - Apr 25, 2019	-32.29% Mar 9, 2000 - Mar 20, 2000
#8	-17.48% Jul 26, 2019 - Sep 16, 2019	-31.79% Dec 17, 1999 - Jan 10, 2000
#9	-17.26% May 28, 2019 - Jun 20, 2019	-29.49% Mar 18, 2014 - Nov 6, 2014
#10	-11.38% Jun 20, 2019 - Jun 27, 2019	-24.69% Aug 15, 2000 - Sep 22, 2000
#11	-10.33% Nov 24, 2015 - Dec 29, 2015	-22.54% Mar 7, 2024 - Sep 11, 2024
#12	-9.37% Jul 2, 2019 - Jul 26, 2019	-21.42% Feb 11, 2021 - Jun 11, 2021
#13	-8.83% Dec 4, 2019 - Dec 10, 2019	-20.19% Jul 17, 2000 - Jul 26, 2000
#14	-8.26% Dec 31, 2025 - Jan 20, 2026	-18.15% Oct 15, 2020 - Dec 17, 2020
#15	-7.23% Feb 5, 2025 - Feb 10, 2025	-17.53% Jan 10, 2000 - Jan 25, 2000