AXSM vs DOCU

Comparison between Axsome Therapeutics Inc (AXSM, Company) and DocuSign Inc (DOCU, Company).

AXSM is from the Healthcare sector, while DOCU is from the Technology sector.

5-Year PerformanceAXSM has outperformed DOCU, delivering a return of +56.4% compared to -26.4%

AXSM vs DOCU - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	AXSM(COMPANY)	DOCU(COMPANY)
Market Cap	$11B	$11B
Max Drawdown	86.65%	87.57%
Sharpe Ratio	1.80	-0.15
5Y Beta	0.65	1.07
Industry	Biotechnology	Software - Application
P/E Ratio	-57.45	36.48
Forward P/E	333.33	13.02
5Y EPS CAGR	4.27%	N/A
Debt to Equity	225.63%	0.00%
Free Cash Flow Yield	-0.64%	9.99%

Market Cap

Winner

AXSM

$11B

DOCU

$11B

Max Drawdown

Winner

AXSM

86.65%

DOCU

87.57%

Sharpe Ratio

Winner

AXSM

1.80

DOCU

-0.15

5Y Beta

Winner

AXSM

0.65

DOCU

1.07

Industry

AXSM

Biotechnology

DOCU

Software - Application

P/E Ratio

Winner

AXSM

-57.45

DOCU

36.48

Forward P/E

AXSM

333.33

Winner

DOCU

13.02

5Y EPS CAGR

AXSM

4.27%

DOCU

N/A

Debt to Equity

AXSM

225.63%

Winner

DOCU

0.00%

Free Cash Flow Yield

AXSM

-0.64%

Winner

DOCU

9.99%

AXSM vs DOCU - Historical Returns

Returns include dividend reinvestment.

Period	AXSM	DOCU
1 month	-6.40%	+28.51%
3 months	-9.20%	+42.20%
6 months	+17.92%	+42.99%
1 year	+95.34%	-9.36%
5 years(CAGR)	+56.37%	-26.36%
10 years(CAGR)	+39.89%	+5.93%
Max(CAGR)	+34.70%	+5.93%

AXSM

-6.40%

Winner

DOCU

+28.51%

AXSM

-9.20%

Winner

DOCU

+42.20%

AXSM

+17.92%

Winner

DOCU

+42.99%

Winner

AXSM

+95.34%

DOCU

-9.36%

5Y(CAGR)

Winner

AXSM

+56.37%

DOCU

-26.36%

10Y(CAGR)

Winner

AXSM

+39.89%

DOCU

+5.93%

Max(CAGR)

Winner

AXSM

+34.70%

DOCU

+5.93%

AXSM vs DOCU - Annual Returns (2015 - 2026)

Returns include dividend reinvestment.

Year	AXSM	DOCU
2026	+19.58%	-1.17%
2025	+109.16%	-24.29%
2024	+9.80%	+57.73%
2023	+8.55%	+4.76%
2022	+103.89%	-64.70%
2021	-53.61%	-31.52%
2020	-19.58%	+192.89%
2019	+3756.72%	+81.55%
2018	-48.49%	+0.88%
2017	-13.18%	N/A
2016	-44.63%	N/A
2015	+6.06%	N/A

AXSM vs DOCU Drawdown Comparison

The maximum drawdown for AXSM was -86.65%, occurring on Dec 27, 2018. Recovery took 809 trading sessions.

The maximum drawdown for DOCU was -87.57%, occurring on Oct 27, 2023. This drawdown has not yet recovered.

The current AXSM drawdown is -16.26%. The current DOCU drawdown is -79.33%.

Rank	AXSM	DOCU
#1	-86.65% Jan 5, 2016 - Mar 25, 2019	-87.57% Sep 3, 2021 - Oct 27, 2023
#2	-81.26% Dec 26, 2019 - Jan 30, 2025	-44.88% Aug 29, 2018 - Nov 4, 2019
#3	-42.70% Sep 16, 2019 - Nov 19, 2019	-32.98% Sep 1, 2020 - Jun 18, 2021
#4	-30.56% Feb 21, 2025 - Nov 6, 2025	-24.93% Feb 19, 2020 - Mar 31, 2020
#5	-18.50% Jan 21, 2026 - Apr 30, 2026	-19.14% Jun 15, 2018 - Aug 24, 2018
#6	-17.65% Jun 12, 2026 - Aug 6, 2026	-15.75% Aug 4, 2020 - Sep 1, 2020
#7	-17.63% Mar 25, 2019 - Apr 25, 2019	-14.50% Mar 31, 2020 - Apr 13, 2020
#8	-17.48% Jul 26, 2019 - Sep 16, 2019	-10.55% Jul 9, 2020 - Jul 30, 2020
#9	-17.26% May 28, 2019 - Jun 20, 2019	-7.68% Jul 23, 2021 - Sep 3, 2021
#10	-11.38% Jun 20, 2019 - Jun 27, 2019	-5.46% May 15, 2018 - May 24, 2018
#11	-10.33% Nov 24, 2015 - Dec 29, 2015	-5.44% Jun 2, 2020 - Jun 10, 2020
#12	-9.37% Jul 2, 2019 - Jul 26, 2019	-4.90% Jan 8, 2020 - Jan 29, 2020
#13	-8.83% Dec 4, 2019 - Dec 10, 2019	-4.86% May 22, 2020 - May 29, 2020
#14	-8.26% Dec 31, 2025 - Jan 20, 2026	-4.76% Dec 6, 2019 - Jan 2, 2020
#15	-7.23% Feb 5, 2025 - Feb 10, 2025	-4.68% Jul 7, 2021 - Jul 19, 2021