AGNC vs AXSM

Comparison between AGNC Investment Corp (AGNC, Company) and Axsome Therapeutics Inc (AXSM, Company).

AGNC is from the Real Estate sector, while AXSM is from the Healthcare sector.

5-Year PerformanceAXSM has outperformed AGNC, delivering a return of +31.1% compared to +2.1%

AGNC vs AXSM - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	AGNC(COMPANY)	AXSM(COMPANY)
Market Cap	$12B	$12B
Max Drawdown	81.08%	86.65%
Sharpe Ratio	1.54	2.05
5Y Beta	0.67	0.68
Industry	Reit - Mortgage	Biotechnology
P/E Ratio	7.79	-63.07
Forward P/E	6.46	333.33
PEG Ratio	0.05	N/A
Dividend Yield	14.10%	N/A
5Y Dividends CAGR	1.61%	N/A
5Y EPS CAGR	-25.22%	6.89%
Debt to Equity	0.00%	344.13%
Free Cash Flow Yield	7.03%	-0.59%

Market Cap

Winner

AGNC

$12B

AXSM

$12B

Max Drawdown

Winner

AGNC

81.08%

AXSM

86.65%

Sharpe Ratio

AGNC

1.54

Winner

AXSM

2.05

5Y Beta

Winner

AGNC

0.67

AXSM

0.68

Industry

AGNC

Reit - Mortgage

AXSM

Biotechnology

P/E Ratio

AGNC

7.79

Winner

AXSM

-63.07

Forward P/E

Winner

AGNC

6.46

AXSM

333.33

PEG Ratio

AGNC

0.05

AXSM

N/A

Dividend Yield

AGNC

14.10%

AXSM

N/A

5Y Dividends CAGR

AGNC

1.61%

AXSM

N/A

5Y EPS CAGR

AGNC

-25.22%

Winner

AXSM

6.89%

Debt to Equity

Winner

AGNC

0.00%

AXSM

344.13%

Free Cash Flow Yield

Winner

AGNC

7.03%

AXSM

-0.59%

AGNC vs AXSM - Historical Returns

Returns include dividend reinvestment.

Period	AGNC	AXSM
1 month	-4.28%	+25.14%
3 months	-4.09%	+43.10%
6 months	+6.35%	+55.33%
1 year	+34.85%	+125.54%
5 years(CAGR)	+2.09%	+31.13%
10 years(CAGR)	+6.53%	+40.16%
Max(CAGR)	+11.38%	+36.72%

AGNC

-4.28%

Winner

AXSM

+25.14%

AGNC

-4.09%

Winner

AXSM

+43.10%

AGNC

+6.35%

Winner

AXSM

+55.33%

AGNC

+34.85%

Winner

AXSM

+125.54%

5Y(CAGR)

AGNC

+2.09%

Winner

AXSM

+31.13%

10Y(CAGR)

AGNC

+6.53%

Winner

AXSM

+40.16%

Max(CAGR)

AGNC

+11.38%

Winner

AXSM

+36.72%

AGNC vs AXSM - Annual Returns (2008 - 2026)

Returns include dividend reinvestment.

Year	AGNC	AXSM
2026	+0.47%	+31.24%
2025	+33.83%	+109.16%
2024	+10.58%	+9.80%
2023	+8.86%	+8.55%
2022	-23.81%	+103.89%
2021	+6.67%	-53.61%
2020	-2.19%	-19.58%
2019	+12.74%	+3756.72%
2018	-1.28%	-48.49%
2017	+20.77%	-13.18%
2016	+15.72%	-44.63%
2015	-11.87%	+6.06%
2014	+26.43%	N/A
2013	-25.71%	N/A
2012	+19.74%	N/A
2011	+18.83%	N/A
2010	+31.30%	N/A
2009	+56.39%	N/A
2008	+25.51%	N/A

AGNC vs AXSM Drawdown Comparison

The maximum drawdown for AGNC was -54.54%, occurring on Oct 10, 2022. Recovery took 1109 trading sessions.

The maximum drawdown for AXSM was -86.65%, occurring on Dec 27, 2018. Recovery took 809 trading sessions.

The current AGNC drawdown is -9.77%. The current AXSM drawdown is -0.61%.

Rank	AGNC	AXSM
#1	-54.54% Jun 8, 2021 - Nov 5, 2025	-86.65% Jan 5, 2016 - Mar 25, 2019
#2	-51.76% Feb 20, 2020 - Apr 16, 2021	-81.26% Dec 26, 2019 - Jan 30, 2025
#3	-37.29% Apr 30, 2013 - Apr 4, 2017	-42.70% Sep 16, 2019 - Nov 19, 2019
#4	-31.04% Dec 31, 2008 - Jun 9, 2009	-30.56% Feb 21, 2025 - Nov 6, 2025
#5	-28.81% May 16, 2008 - Sep 8, 2008	-18.50% Jan 21, 2026 - Apr 30, 2026
#6	-22.42% Sep 8, 2008 - Nov 4, 2008	-17.63% Mar 25, 2019 - Apr 25, 2019
#7	-18.99% Sep 17, 2012 - Mar 28, 2013	-17.48% Jul 26, 2019 - Sep 16, 2019
#8	-18.68% Jan 27, 2026 - Mar 27, 2026	-17.26% May 28, 2019 - Jun 20, 2019
#9	-15.90% Oct 17, 2017 - Nov 7, 2019	-11.38% Jun 20, 2019 - Jun 27, 2019
#10	-15.36% Sep 23, 2009 - Mar 22, 2010	-10.33% Nov 24, 2015 - Dec 29, 2015
#11	-11.69% Jul 6, 2011 - Dec 6, 2011	-9.37% Jul 2, 2019 - Jul 26, 2019
#12	-11.06% Nov 5, 2008 - Nov 25, 2008	-8.83% Dec 4, 2019 - Dec 10, 2019
#13	-10.94% Apr 29, 2010 - Jun 14, 2010	-8.26% Dec 31, 2025 - Jan 20, 2026
#14	-10.17% Dec 3, 2008 - Dec 19, 2008	-7.23% Feb 5, 2025 - Feb 10, 2025
#15	-7.92% Apr 27, 2017 - Jun 9, 2017	-6.21% Nov 28, 2025 - Dec 19, 2025