AXSM vs KNX

Comparison between Axsome Therapeutics Inc (AXSM, Company) and Knight-Swift Transportation Holdings Inc - Class A (KNX, Company).

AXSM is from the Healthcare sector, while KNX is from the Industrials sector.

5-Year PerformanceAXSM has outperformed KNX, delivering a return of +31.1% compared to +10.4%

AXSM vs KNX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	AXSM(COMPANY)	KNX(COMPANY)
Market Cap	$12B	$12B
Max Drawdown	86.65%	69.70%
Sharpe Ratio	2.05	1.55
5Y Beta	0.68	1.06
Industry	Biotechnology	Trucking
P/E Ratio	-63.07	354.22
Forward P/E	333.33	37.17
Dividend Yield	N/A	1.06%
5Y Dividends CAGR	N/A	23.52%
5Y EPS CAGR	6.89%	-40.58%
Debt to Equity	344.13%	24.85%
Free Cash Flow Yield	-0.59%	10.78%

Market Cap

Winner

AXSM

$12B

KNX

$12B

Max Drawdown

AXSM

86.65%

Winner

KNX

69.70%

Sharpe Ratio

Winner

AXSM

2.05

KNX

1.55

5Y Beta

Winner

AXSM

0.68

KNX

1.06

Industry

AXSM

Biotechnology

KNX

Trucking

P/E Ratio

Winner

AXSM

-63.07

KNX

354.22

Forward P/E

AXSM

333.33

Winner

KNX

37.17

Dividend Yield

AXSM

N/A

KNX

1.06%

5Y Dividends CAGR

AXSM

N/A

KNX

23.52%

5Y EPS CAGR

Winner

AXSM

6.89%

KNX

-40.58%

Debt to Equity

AXSM

344.13%

Winner

KNX

24.85%

Free Cash Flow Yield

AXSM

-0.59%

Winner

KNX

10.78%

AXSM vs KNX - Historical Returns

Returns include dividend reinvestment.

Period	AXSM	KNX
1 month	+25.14%	+14.70%
3 months	+43.10%	+18.34%
6 months	+55.33%	+63.15%
1 year	+125.54%	+71.85%
5 years(CAGR)	+31.13%	+10.35%
10 years(CAGR)	+40.16%	+12.10%
Max(CAGR)	+36.72%	+14.45%

Winner

AXSM

+25.14%

KNX

+14.70%

Winner

AXSM

+43.10%

KNX

+18.34%

AXSM

+55.33%

Winner

KNX

+63.15%

Winner

AXSM

+125.54%

KNX

+71.85%

5Y(CAGR)

Winner

AXSM

+31.13%

KNX

+10.35%

10Y(CAGR)

Winner

AXSM

+40.16%

KNX

+12.10%

Max(CAGR)

Winner

AXSM

+36.72%

KNX

+14.45%

AXSM vs KNX - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	AXSM	KNX
2026	+31.24%	+42.56%
2025	+109.16%	+0.70%
2024	+9.80%	-6.49%
2023	+8.55%	+9.76%
2022	+103.89%	-12.67%
2021	-53.61%	+50.13%
2020	-19.58%	+13.98%
2019	+3756.72%	+39.72%
2018	-48.49%	-43.43%
2017	-13.18%	+31.17%
2016	-44.63%	+39.54%
2015	+6.06%	-27.51%
2014	N/A	+87.93%
2013	N/A	+22.74%
2012	N/A	-2.37%
2011	N/A	-18.22%
2010	N/A	+4.05%
2009	N/A	+20.25%
2008	N/A	+11.17%
2007	N/A	-14.54%
2006	N/A	-18.02%
2005	N/A	+27.24%
2004	N/A	+42.65%
2003	N/A	+21.45%
2002	N/A	+10.58%
2001	N/A	+116.69%
2000	N/A	+15.34%
1999	N/A	+24.58%

AXSM vs KNX Drawdown Comparison

The maximum drawdown for AXSM was -86.65%, occurring on Dec 27, 2018. Recovery took 809 trading sessions.

The maximum drawdown for KNX was -67.98%, occurring on Oct 6, 2011. Recovery took 799 trading sessions.

The current AXSM drawdown is -0.61%.

Rank	AXSM	KNX
#1	-86.65% Jan 5, 2016 - Mar 25, 2019	-67.98% Jul 26, 2010 - Sep 26, 2013
#2	-81.26% Dec 26, 2019 - Jan 30, 2025	-51.57% Mar 16, 2018 - Mar 30, 2021
#3	-42.70% Sep 16, 2019 - Nov 19, 2019	-46.91% Mar 20, 2015 - Nov 14, 2016
#4	-30.56% Feb 21, 2025 - Nov 6, 2025	-42.78% Nov 23, 2005 - Apr 19, 2010
#5	-18.50% Jan 21, 2026 - Apr 30, 2026	-38.04% Feb 2, 2023 - Feb 20, 2026
#6	-17.63% Mar 25, 2019 - Apr 25, 2019	-36.78% Jan 30, 2002 - Apr 25, 2003
#7	-17.48% Jul 26, 2019 - Sep 16, 2019	-32.24% Jul 17, 2001 - Oct 23, 2001
#8	-17.26% May 28, 2019 - Jun 20, 2019	-28.80% Dec 29, 2021 - Feb 2, 2023
#9	-11.38% Jun 20, 2019 - Jun 27, 2019	-25.74% Apr 25, 2000 - Dec 28, 2000
#10	-10.33% Nov 24, 2015 - Dec 29, 2015	-25.48% Feb 7, 2001 - Apr 9, 2001
#11	-9.37% Jul 2, 2019 - Jul 26, 2019	-24.96% Mar 8, 2005 - Nov 2, 2005
#12	-8.83% Dec 4, 2019 - Dec 10, 2019	-20.97% Sep 4, 2003 - Jun 30, 2004
#13	-8.26% Dec 31, 2025 - Jan 20, 2026	-20.69% Dec 8, 2016 - Aug 28, 2017
#14	-7.23% Feb 5, 2025 - Feb 10, 2025	-17.93% Mar 4, 2026 - Apr 16, 2026
#15	-6.21% Nov 28, 2025 - Dec 19, 2025	-17.50% May 17, 2001 - Jun 27, 2001