AG vs IONS

Comparison between First Majestic Silver Corporation (AG, Company) and Ionis Pharmaceuticals Inc (IONS, Company).

AG is from the Basic Materials sector, while IONS is from the Healthcare sector.

5-Year PerformanceAG has outperformed IONS, delivering a return of +8.3% compared to +7.1%

AG vs IONS - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	AG(COMPANY)	IONS(COMPANY)
Market Cap	$9.40B	$9.36B
Max Drawdown	90.20%	91.72%
Sharpe Ratio	1.37	0.80
5Y Beta	1.43	0.66
Industry	Silver	Biotechnology
P/E Ratio	26.93	-22.42
Forward P/E	20.41	90.91
Dividend Yield	0.24%	N/A
5Y Dividends CAGR	51.06%	N/A
5Y EPS CAGR	14.30%	-8.41%
Debt to Equity	11.17%	0.00%
Free Cash Flow Yield	7.40%	-5.99%

Market Cap

Winner

$9.40B

IONS

$9.36B

Max Drawdown

Winner

90.20%

IONS

91.72%

Sharpe Ratio

Winner

1.37

IONS

0.80

5Y Beta

1.43

Winner

IONS

0.66

Industry

Silver

IONS

Biotechnology

P/E Ratio

26.93

Winner

IONS

-22.42

Forward P/E

Winner

20.41

IONS

90.91

Dividend Yield

0.24%

IONS

N/A

5Y Dividends CAGR

51.06%

IONS

N/A

5Y EPS CAGR

Winner

14.30%

IONS

-8.41%

Debt to Equity

11.17%

Winner

IONS

0.00%

Free Cash Flow Yield

Winner

7.40%

IONS

-5.99%

AG vs IONS - Historical Returns

Returns include dividend reinvestment.

Period	AG	IONS
1 month	+14.39%	-1.55%
3 months	-21.70%	-28.00%
6 months	-18.20%	-30.68%
1 year	+110.28%	+29.63%
5 years(CAGR)	+8.34%	+7.08%
10 years(CAGR)	+0.50%	+4.78%
Max(CAGR)	+8.38%	+6.34%

Winner

+14.39%

IONS

-1.55%

Winner

-21.70%

IONS

-28.00%

Winner

-18.20%

IONS

-30.68%

Winner

+110.28%

IONS

+29.63%

5Y(CAGR)

Winner

+8.34%

IONS

+7.08%

10Y(CAGR)

+0.50%

Winner

IONS

+4.78%

Max(CAGR)

Winner

+8.38%

IONS

+6.34%

AG vs IONS - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	AG	IONS
2026	+16.94%	-29.87%
2025	+180.79%	+128.05%
2024	-7.92%	-33.88%
2023	-26.61%	+34.62%
2022	-23.42%	+15.86%
2021	-21.89%	-46.41%
2020	+9.98%	-7.14%
2019	+103.65%	+12.35%
2018	-18.42%	+9.77%
2017	-16.58%	+6.25%
2016	+123.10%	-22.45%
2015	-37.36%	+0.58%
2014	-51.96%	+54.85%
2013	-53.69%	+268.21%
2012	+14.46%	+44.00%
2011	+7.95%	-29.93%
2010	+254.15%	-10.20%
2009	+94.09%	-23.22%
2008	-62.37%	-7.80%
2007	+2.20%	+44.10%
2006	+7.18%	+111.81%
2005	N/A	-9.66%
2004	N/A	-13.36%
2003	N/A	-4.97%
2002	N/A	-68.69%
2001	N/A	+130.55%
2000	N/A	+77.49%
1999	N/A	-44.34%

AG vs IONS Drawdown Comparison

The maximum drawdown for AG was -90.20%, occurring on Jan 19, 2016. Recovery took 3722 trading sessions.

The maximum drawdown for IONS was -91.43%, occurring on Mar 18, 2003. Recovery took 3357 trading sessions.

The current AG drawdown is -41.34%. The current IONS drawdown is -35.41%.

Rank	AG	IONS
#1	-90.20% Apr 5, 2011 - Jan 23, 2026	-91.43% Mar 6, 2000 - Jul 11, 2013
#2	-87.80% Mar 3, 2008 - Sep 20, 2010	-73.25% Mar 19, 2015 - Mar 14, 2019
#3	-53.01% Feb 27, 2026 - Jul 31, 2026	-70.39% Apr 8, 2019 - Feb 6, 2026
#4	-46.53% Feb 26, 2007 - Mar 3, 2008	-68.14% Dec 2, 1999 - Mar 1, 2000
#5	-32.76% Jan 3, 2011 - Mar 1, 2011	-61.05% Feb 21, 2014 - Dec 10, 2014
#6	-22.80% Jan 28, 2026 - Feb 20, 2026	-40.15% Feb 6, 2026 - Jul 31, 2026
#7	-17.70% Mar 8, 2011 - Mar 21, 2011	-28.35% Jul 12, 2013 - Sep 19, 2013
#8	-16.03% Nov 8, 2010 - Nov 22, 2010	-20.89% Sep 23, 2013 - Nov 27, 2013
#9	-15.35% Jan 18, 2007 - Feb 16, 2007	-19.78% Jan 12, 2015 - Mar 19, 2015
#10	-15.18% Oct 13, 2010 - Oct 29, 2010	-11.84% Dec 12, 2014 - Dec 19, 2014
#11	-12.71% Dec 14, 2010 - Dec 29, 2010	-11.49% Dec 19, 2014 - Jan 5, 2015
#12	-10.11% Jan 3, 2007 - Jan 12, 2007	-8.95% Jan 31, 2014 - Feb 13, 2014
#13	-9.53% Dec 6, 2010 - Dec 14, 2010	-8.58% Nov 11, 1999 - Nov 17, 1999
#14	-7.61% Nov 30, 2006 - Dec 15, 2006	-7.67% Jan 22, 2014 - Jan 31, 2014
#15	-4.00% Nov 24, 2010 - Nov 30, 2010	-7.49% Dec 23, 2013 - Jan 8, 2014