AEIS vs IONS

Comparison between Advanced Energy Industries Inc (AEIS, Company) and Ionis Pharmaceuticals Inc (IONS, Company).

AEIS is from the Industrials sector, while IONS is from the Healthcare sector.

5-Year PerformanceAEIS has outperformed IONS, delivering a return of +30.2% compared to +14.6%

AEIS vs IONS - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	AEIS(COMPANY)	IONS(COMPANY)
Market Cap	$13B	$13B
Max Drawdown	92.51%	91.72%
Sharpe Ratio	2.36	1.94
5Y Beta	1.95	0.74
Industry	Electrical Equipment & Parts	Biotechnology
P/E Ratio	67.36	-73.64
Forward P/E	41.67	90.91
PEG Ratio	0.42	-1.55
Dividend Yield	0.12%	N/A
5Y Dividends CAGR	37.97%	N/A
5Y EPS CAGR	4.44%	-21.44%
Debt to Equity	82.09%	88.01%
Free Cash Flow Yield	0.53%	-7.54%
P/S Ratio	6.77	11.83
P/B Ratio	9.81	25.46

Market Cap

Winner

AEIS

$13B

IONS

$13B

Max Drawdown

AEIS

92.51%

Winner

IONS

91.72%

Sharpe Ratio

Winner

AEIS

2.36

IONS

1.94

5Y Beta

AEIS

1.95

Winner

IONS

0.74

Industry

AEIS

Electrical Equipment & Parts

IONS

Biotechnology

P/E Ratio

AEIS

67.36

Winner

IONS

-73.64

Forward P/E

Winner

AEIS

41.67

IONS

90.91

PEG Ratio

AEIS

0.42

Winner

IONS

-1.55

Dividend Yield

AEIS

0.12%

IONS

N/A

5Y Dividends CAGR

AEIS

37.97%

IONS

N/A

5Y EPS CAGR

Winner

AEIS

4.44%

IONS

-21.44%

Debt to Equity

Winner

AEIS

82.09%

IONS

88.01%

Free Cash Flow Yield

Winner

AEIS

0.53%

IONS

-7.54%

P/S Ratio

Winner

AEIS

6.77

IONS

11.83

P/B Ratio

Winner

AEIS

9.81

IONS

25.46

AEIS vs IONS - Historical Returns

Returns include dividend reinvestment.

Period	AEIS	IONS
1 month	-10.66%	-1.41%
3 months	+9.68%	-6.10%
6 months	+70.32%	+5.77%
1 year	+190.45%	+132.15%
5 years(CAGR)	+30.24%	+14.63%
10 years(CAGR)	+26.05%	+9.19%
Max(CAGR)	+8.28%	+7.63%

AEIS

-10.66%

Winner

IONS

-1.41%

Winner

AEIS

+9.68%

IONS

-6.10%

Winner

AEIS

+70.32%

IONS

+5.77%

Winner

AEIS

+190.45%

IONS

+132.15%

5Y(CAGR)

Winner

AEIS

+30.24%

IONS

+14.63%

10Y(CAGR)

Winner

AEIS

+26.05%

IONS

+9.19%

Max(CAGR)

Winner

AEIS

+8.28%

IONS

+7.63%

AEIS vs IONS - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	AEIS	IONS
2026	+55.28%	-5.01%
2025	+82.04%	+128.05%
2024	+9.24%	-33.88%
2023	+27.85%	+34.62%
2022	-7.15%	+15.86%
2021	-6.68%	-46.41%
2020	+35.21%	-7.14%
2019	+64.24%	+12.35%
2018	-38.15%	+9.77%
2017	+23.14%	+6.25%
2016	+102.25%	-22.45%
2015	+16.58%	+0.58%
2014	+3.58%	+54.85%
2013	+59.86%	+268.21%
2012	+25.31%	+44.00%
2011	-22.47%	-29.93%
2010	-12.40%	-10.20%
2009	+51.25%	-23.22%
2008	-22.02%	-7.80%
2007	-30.24%	+44.10%
2006	+56.47%	+111.81%
2005	+33.22%	-9.66%
2004	-65.39%	-13.36%
2003	+84.36%	-4.97%
2002	-52.71%	-68.69%
2001	+32.87%	+130.55%
2000	-50.42%	+77.49%
1999	+15.53%	-44.34%

AEIS vs IONS Drawdown Comparison

The maximum drawdown for AEIS was -92.51%, occurring on Mar 9, 2009. Recovery took 4316 trading sessions.

The maximum drawdown for IONS was -91.43%, occurring on Mar 18, 2003. Recovery took 3357 trading sessions.

The current AEIS drawdown is -11.43%. The current IONS drawdown is -12.51%.

Rank	AEIS	IONS
#1	-92.51% Mar 1, 2000 - Apr 27, 2017	-91.43% Mar 6, 2000 - Jul 11, 2013
#2	-62.28% Oct 27, 2017 - Nov 23, 2020	-73.25% Mar 19, 2015 - Mar 14, 2019
#3	-43.73% Jan 19, 2021 - Jul 31, 2023	-70.39% Apr 8, 2019 - Feb 6, 2026
#4	-39.87% Feb 19, 2025 - Jun 24, 2025	-68.14% Dec 2, 1999 - Mar 1, 2000
#5	-32.81% Aug 1, 2023 - Jan 21, 2025	-61.05% Feb 21, 2014 - Dec 10, 2014
#6	-24.20% Jun 8, 2017 - Oct 12, 2017	-28.35% Jul 12, 2013 - Sep 19, 2013
#7	-23.57% Nov 2, 1999 - Dec 22, 1999	-20.89% Sep 23, 2013 - Nov 27, 2013
#8	-20.17% Jan 26, 2000 - Feb 16, 2000	-19.78% Jan 12, 2015 - Mar 19, 2015
#9	-16.35% Nov 5, 2025 - Jan 5, 2026	-19.45% Feb 6, 2026 - Mar 24, 2026
#10	-16.30% Mar 24, 2026 - Apr 8, 2026	-11.84% Dec 12, 2014 - Dec 19, 2014
#11	-14.58% Mar 2, 2026 - Mar 24, 2026	-11.49% Dec 19, 2014 - Jan 5, 2015
#12	-12.84% Jan 21, 2025 - Feb 19, 2025	-8.95% Jan 31, 2014 - Feb 13, 2014
#13	-12.82% May 1, 2026 - May 13, 2026	-8.58% Nov 11, 1999 - Nov 17, 1999
#14	-11.29% Dec 31, 1999 - Jan 18, 2000	-7.67% Jan 22, 2014 - Jan 31, 2014
#15	-10.57% Aug 13, 2025 - Sep 18, 2025	-7.49% Dec 23, 2013 - Jan 8, 2014