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ZBIO vs AMLX

Comparison between Zenas Biopharma Inc (ZBIO, Company) and Amylyx Pharmaceuticals Inc (AMLX, Company).

Both ZBIO and AMLX are from the Healthcare sector.

ZBIO vs AMLX - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap
ZBIO
$1.96B
Winner
AMLX
$1.97B
Max Drawdown
Winner
ZBIO
74.96%
AMLX
96.04%
Sharpe Ratio
ZBIO
1.29
Winner
AMLX
1.50
5Y Beta
ZBIO
1.25
Winner
AMLX
1.15
Industry
ZBIO
Biotechnology
AMLX
Drug Manufacturers - Specialty & Generic
P/E Ratio
ZBIO
-3.85
Winner
AMLX
-12.20
Forward P/E
ZBIO
N/A
AMLX
2.77
Debt to Equity
ZBIO
0.00%
AMLX
0.00%
Free Cash Flow Yield
ZBIO
-10.71%
Winner
AMLX
-6.13%

ZBIO vs AMLX - Historical Returns

Returns include dividend reinvestment.

1M
Winner
ZBIO
+53.38%
AMLX
+7.45%
3M
Winner
ZBIO
+67.60%
AMLX
+1.56%
6M
Winner
ZBIO
+54.26%
AMLX
+11.61%
1Y
ZBIO
+98.40%
Winner
AMLX
+109.65%
5Y(CAGR)
ZBIO
N/A
AMLX
-0.59%
Max(CAGR)
Winner
ZBIO
+33.40%
AMLX
-0.59%

ZBIO vs AMLX - Annual Returns (2022 - 2026)

Returns include dividend reinvestment.

YearZBIOAMLX
2026-10.17%+54.03%
2025+303.00%+208.95%
2024-54.88%-74.75%
2023N/A-59.09%
2022N/A+104.48%

ZBIO vs AMLX Drawdown Comparison

The maximum drawdown for ZBIO was -74.96%, occurring on Jan 28, 2025. Recovery took 240 trading sessions.

The maximum drawdown for AMLX was -96.04%, occurring on Jun 18, 2024. This drawdown has not yet recovered.

The current ZBIO drawdown is -28.21%. The current AMLX drawdown is -57.02%.

RankZBIOAMLX
#1-74.96%
Oct 22, 2024 - Oct 8, 2025
-96.04%
Jan 27, 2023 - Jun 18, 2024
#2-64.79%
Dec 24, 2025 - Jan 6, 2026
-79.18%
Feb 28, 2022 - Oct 10, 2022
#3-19.71%
Dec 12, 2025 - Dec 22, 2025
-17.59%
Feb 1, 2022 - Feb 18, 2022
#4-14.88%
Nov 26, 2025 - Dec 12, 2025
-15.23%
Dec 1, 2022 - Jan 24, 2023
#5-13.92%
Oct 9, 2025 - Oct 27, 2025
-13.39%
Oct 26, 2022 - Nov 25, 2022
#6-12.01%
Sep 24, 2024 - Oct 15, 2024
-12.97%
Jan 19, 2022 - Jan 31, 2022
#7-11.92%
Oct 27, 2025 - Nov 6, 2025
-7.90%
Jan 13, 2022 - Jan 19, 2022
#8-6.22%
Nov 19, 2025 - Nov 24, 2025
-7.47%
Jan 7, 2022 - Jan 11, 2022
#9-3.47%
Sep 13, 2024 - Sep 20, 2024
-5.42%
Nov 25, 2022 - Dec 1, 2022
#10-3.39%
Nov 7, 2025 - Nov 11, 2025
-3.44%
Feb 22, 2022 - Feb 24, 2022
#11-2.23%
Nov 12, 2025 - Nov 17, 2025
-3.19%
Oct 10, 2022 - Oct 13, 2022
#12-2.16%
Sep 20, 2024 - Sep 24, 2024
-2.79%
Oct 13, 2022 - Oct 17, 2022
#13-1.27%
Oct 15, 2024 - Oct 17, 2024
-1.41%
Oct 18, 2022 - Oct 21, 2022
#14-0.56%
Oct 17, 2024 - Oct 21, 2024
-1.06%
Jan 25, 2023 - Jan 27, 2023

Correlation

Correlation between ZBIO and AMLX is 0.76 which considered as a strong positive correlation - the stocks tend to move together.

0.76
-101

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