YSG vs PALI

Comparison between Yatsen Holding Ltd (YSG, Company) and Palisade Bio Inc (PALI, Company).

YSG is from the Consumer Defensive sector, while PALI is from the Healthcare sector.

5-Year PerformanceYSG has outperformed PALI, delivering a return of -42.6% compared to -77.7%

YSG vs PALI - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	YSG(COMPANY)	PALI(COMPANY)
Market Cap	$282M	$281M
Max Drawdown	98.41%	100.00%
Sharpe Ratio	-0.81	1.32
5Y Beta	1.02	0.00
Industry	Household & Personal Products	Biotechnology
P/E Ratio	-24.41	-9.72
5Y EPS CAGR	-58.33%	N/A
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-6.93%	-4.41%
P/S Ratio	0.06	11.78
P/B Ratio	0.66	2.29

Market Cap

Winner

YSG

$282M

PALI

$281M

Max Drawdown

Winner

YSG

98.41%

PALI

100.00%

Sharpe Ratio

YSG

-0.81

Winner

PALI

1.32

5Y Beta

YSG

1.02

Winner

PALI

0.00

Industry

YSG

Household & Personal Products

PALI

Biotechnology

P/E Ratio

Winner

YSG

-24.41

PALI

-9.72

5Y EPS CAGR

YSG

-58.33%

PALI

N/A

Debt to Equity

YSG

0.00%

PALI

0.00%

Free Cash Flow Yield

YSG

-6.93%

Winner

PALI

-4.41%

P/S Ratio

Winner

YSG

0.06

PALI

11.78

P/B Ratio

Winner

YSG

0.66

PALI

2.29

YSG vs PALI - Historical Returns

Returns include dividend reinvestment.

Period	YSG	PALI
1 month	+7.24%	-10.94%
3 months	-22.64%	-15.76%
6 months	-28.18%	-11.86%
1 year	-66.49%	+147.83%
5 years(CAGR)	-42.64%	-77.66%
10 years(CAGR)	N/A	-70.76%
Max(CAGR)	-45.62%	-51.59%

Winner

YSG

+7.24%

PALI

-10.94%

YSG

-22.64%

Winner

PALI

-15.76%

YSG

-28.18%

Winner

PALI

-11.86%

YSG

-66.49%

Winner

PALI

+147.83%

5Y(CAGR)

Winner

YSG

-42.64%

PALI

-77.66%

10Y(CAGR)

YSG

N/A

PALI

-70.76%

Max(CAGR)

Winner

YSG

-45.62%

PALI

-51.59%

YSG vs PALI - Annual Returns (2006 - 2026)

Returns include dividend reinvestment.

Year	YSG	PALI
2026	-26.65%	-31.60%
2025	+1.30%	+26.34%
2024	+5.99%	-81.00%
2023	-51.87%	-84.55%
2022	-31.46%	-93.11%
2021	-87.07%	-78.96%
2020	-7.61%	-20.00%
2019	N/A	-84.99%
2018	N/A	-84.58%
2017	N/A	-57.46%
2016	N/A	-73.46%
2015	N/A	-63.35%
2014	N/A	-13.92%
2013	N/A	+140.50%
2012	N/A	+9.00%
2011	N/A	-55.53%
2010	N/A	+14.59%
2009	N/A	+7.19%
2008	N/A	-55.00%
2007	N/A	+48.02%
2006	N/A	+50.00%

YSG vs PALI Drawdown Comparison

The maximum drawdown for YSG was -98.41%, occurring on May 24, 2022. This drawdown has not yet recovered.

The maximum drawdown for PALI was -100.00%, occurring on Sep 10, 2025. This drawdown has not yet recovered.

The current YSG drawdown is -97.47%. The current PALI drawdown is -100.00%.

Rank	YSG	PALI
#1	-98.41% Feb 5, 2021 - May 24, 2022	-100.00% Apr 9, 2014 - Sep 10, 2025
#2	-22.32% Nov 20, 2020 - Jan 14, 2021	-88.86% Apr 26, 2007 - Mar 17, 2014
#3	-13.40% Jan 14, 2021 - Feb 3, 2021	-24.62% Jan 10, 2007 - Mar 26, 2007
#4	-3.78% Feb 3, 2021 - Feb 5, 2021	-18.87% Mar 20, 2014 - Apr 9, 2014
#5	N/A	-16.00% Dec 29, 2006 - Jan 10, 2007
#6	N/A	-16.00% Dec 21, 2006 - Dec 29, 2006
#7	N/A	-7.58% Mar 26, 2007 - Apr 13, 2007
#8	N/A	-5.95% Mar 17, 2014 - Mar 20, 2014
#9	N/A	-5.63% Apr 18, 2007 - Apr 26, 2007