XENE vs PTCT

Comparison between Xenon Pharmaceuticals Inc (XENE, Company) and PTC Therapeutics Inc (PTCT, Company).

Both XENE and PTCT are from the Healthcare sector.

5-Year PerformanceXENE has outperformed PTCT, delivering a return of +29.9% compared to +12.7%

XENE vs PTCT - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	XENE(COMPANY)	PTCT(COMPANY)
Market Cap	$6.54B	$6.53B
Max Drawdown	90.43%	94.60%
Sharpe Ratio	1.44	1.27
5Y Beta	0.92	0.99
Industry	Biotechnology	Biotechnology
P/E Ratio	-14.55	-34.15
Forward P/E	N/A	58.82
PEG Ratio	-0.36	0.81
5Y EPS CAGR	40.27%	-16.59%
Debt to Equity	0.00%	-159.00%
Free Cash Flow Yield	-4.70%	-3.46%
P/S Ratio	727.44	7.83
P/B Ratio	4.89	1743.27

Market Cap

Winner

XENE

$6.54B

PTCT

$6.53B

Max Drawdown

Winner

XENE

90.43%

PTCT

94.60%

Sharpe Ratio

Winner

XENE

1.44

PTCT

1.27

5Y Beta

Winner

XENE

0.92

PTCT

0.99

Industry

XENE

Biotechnology

PTCT

Biotechnology

P/E Ratio

XENE

-14.55

Winner

PTCT

-34.15

Forward P/E

XENE

N/A

PTCT

58.82

PEG Ratio

Winner

XENE

-0.36

PTCT

0.81

5Y EPS CAGR

Winner

XENE

40.27%

PTCT

-16.59%

Debt to Equity

XENE

0.00%

Winner

PTCT

-159.00%

Free Cash Flow Yield

XENE

-4.70%

Winner

PTCT

-3.46%

P/S Ratio

XENE

727.44

Winner

PTCT

7.83

P/B Ratio

Winner

XENE

4.89

PTCT

1743.27

XENE vs PTCT - Historical Returns

Returns include dividend reinvestment.

Period	XENE	PTCT
1 month	+28.83%	+7.17%
3 months	+14.63%	+9.51%
6 months	+67.53%	+8.33%
1 year	+111.83%	+63.11%
5 years(CAGR)	+29.95%	+12.71%
10 years(CAGR)	+24.13%	+27.07%
Max(CAGR)	+17.17%	+12.68%

Winner

XENE

+28.83%

PTCT

+7.17%

Winner

XENE

+14.63%

PTCT

+9.51%

Winner

XENE

+67.53%

PTCT

+8.33%

Winner

XENE

+111.83%

PTCT

+63.11%

5Y(CAGR)

Winner

XENE

+29.95%

PTCT

+12.71%

10Y(CAGR)

XENE

+24.13%

Winner

PTCT

+27.07%

Max(CAGR)

Winner

XENE

+17.17%

PTCT

+12.68%

XENE vs PTCT - Annual Returns (2013 - 2026)

Returns include dividend reinvestment.

Year	XENE	PTCT
2026	+50.55%	+2.32%
2025	+11.58%	+65.56%
2024	-12.71%	+60.98%
2023	+23.62%	-27.78%
2022	+24.82%	-10.36%
2021	+111.94%	-34.17%
2020	+12.10%	+25.99%
2019	+96.26%	+42.90%
2018	+119.48%	+96.56%
2017	-64.01%	+48.53%
2016	-3.27%	-64.65%
2015	-57.01%	-36.47%
2014	+88.10%	+209.26%
2013	N/A	+2.91%

XENE vs PTCT Drawdown Comparison

The maximum drawdown for XENE was -90.43%, occurring on Nov 14, 2017. Recovery took 1696 trading sessions.

The maximum drawdown for PTCT was -94.60%, occurring on Nov 3, 2016. Recovery took 2689 trading sessions.

The current XENE drawdown is -5.61%. The current PTCT drawdown is -12.32%.

Rank	XENE	PTCT
#1	-90.43% Jan 8, 2015 - Oct 4, 2021	-94.60% Mar 17, 2015 - Nov 21, 2025
#2	-43.59% Feb 9, 2024 - Mar 9, 2026	-56.81% Feb 27, 2014 - Sep 15, 2014
#3	-34.08% May 9, 2023 - Dec 22, 2023	-39.55% Sep 23, 2013 - Jan 15, 2014
#4	-30.14% Nov 5, 2021 - Aug 4, 2022	-27.17% Nov 26, 2025 - Jul 7, 2026
#5	-25.87% Nov 11, 2014 - Dec 11, 2014	-25.36% Sep 26, 2014 - Dec 2, 2014
#6	-18.40% Mar 9, 2026 - Jul 7, 2026	-25.27% Jan 17, 2014 - Feb 20, 2014
#7	-17.08% Mar 1, 2023 - May 3, 2023	-23.59% Jul 18, 2013 - Sep 4, 2013
#8	-16.98% Aug 24, 2022 - Feb 13, 2023	-22.29% Jun 25, 2013 - Jul 17, 2013
#9	-11.44% Oct 15, 2021 - Nov 2, 2021	-19.59% Jan 20, 2015 - Feb 23, 2015
#10	-11.09% Dec 11, 2014 - Dec 29, 2014	-18.21% Sep 10, 2013 - Sep 23, 2013
#11	-9.36% Feb 13, 2023 - Mar 1, 2023	-13.33% Dec 12, 2014 - Dec 19, 2014
#12	-8.58% Jan 8, 2024 - Feb 8, 2024	-12.83% Jul 9, 2026 - Jul 14, 2026
#13	-8.27% Aug 10, 2022 - Aug 24, 2022	-10.21% Dec 19, 2014 - Jan 13, 2015
#14	-6.08% Dec 29, 2014 - Jan 7, 2015	-6.13% Feb 25, 2015 - Mar 11, 2015
#15	-5.61% Jul 9, 2026 - Jul 16, 2026	-3.04% Dec 9, 2014 - Dec 11, 2014