VRTX vs TT

Comparison between Vertex Pharmaceuticals Inc (VRTX, Company) and Trane Technologies plc - Class A (TT, Company).

VRTX is from the Healthcare sector, while TT is from the Industrials sector.

5-Year PerformanceTT has outperformed VRTX, delivering a return of +22.0% compared to +14.9%

VRTX vs TT - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	VRTX(COMPANY)	TT(COMPANY)
Market Cap	$109B	$108B
Max Drawdown	91.77%	78.85%
Sharpe Ratio	0.04	0.54
5Y Beta	0.51	0.99
Industry	Biotechnology	Building Products & Equipment
P/E Ratio	25.09	37.37
Forward P/E	22.57	33.11
PEG Ratio	2.11	2.59
Dividend Yield	N/A	0.82%
5Y Dividends CAGR	N/A	12.16%
5Y EPS CAGR	9.89%	14.59%
Debt to Equity	0.00%	53.73%
Free Cash Flow Yield	3.41%	2.74%
P/S Ratio	8.88	5.00
P/B Ratio	5.65	12.56

Market Cap

Winner

VRTX

$109B

$108B

Max Drawdown

VRTX

91.77%

Winner

78.85%

Sharpe Ratio

VRTX

0.04

Winner

0.54

5Y Beta

Winner

VRTX

0.51

0.99

Industry

VRTX

Biotechnology

Building Products & Equipment

P/E Ratio

Winner

VRTX

25.09

37.37

Forward P/E

Winner

VRTX

22.57

33.11

PEG Ratio

Winner

VRTX

2.11

2.59

Dividend Yield

VRTX

N/A

0.82%

5Y Dividends CAGR

VRTX

N/A

12.16%

5Y EPS CAGR

VRTX

9.89%

Winner

14.59%

Debt to Equity

Winner

VRTX

0.00%

53.73%

Free Cash Flow Yield

Winner

VRTX

3.41%

2.74%

P/S Ratio

VRTX

8.88

Winner

5.00

P/B Ratio

Winner

VRTX

5.65

12.56

VRTX vs TT - Historical Returns

Returns include dividend reinvestment.

Period	VRTX	TT
1 month	-3.18%	+3.72%
3 months	-8.72%	+1.64%
6 months	+4.97%	+7.81%
1 year	+0.05%	+15.99%
5 years(CAGR)	+14.85%	+22.02%
10 years(CAGR)	+17.19%	+23.70%
Max(CAGR)	+14.03%	+14.37%

VRTX

-3.18%

Winner

+3.72%

VRTX

-8.72%

Winner

+1.64%

VRTX

+4.97%

Winner

+7.81%

VRTX

+0.05%

Winner

+15.99%

5Y(CAGR)

VRTX

+14.85%

Winner

+22.02%

10Y(CAGR)

VRTX

+17.19%

Winner

+23.70%

Max(CAGR)

VRTX

+14.03%

Winner

+14.37%

VRTX vs TT - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	VRTX	TT
2026	-4.93%	+17.42%
2025	+11.73%	+5.10%
2024	-2.00%	+55.05%
2023	+42.26%	+44.41%
2022	+29.77%	-12.24%
2021	-4.28%	+42.16%
2020	+7.70%	+10.14%
2019	+33.44%	+47.87%
2018	+8.37%	+4.93%
2017	+100.11%	+19.84%
2016	-40.05%	+38.88%
2015	+2.24%	-10.91%
2014	+60.91%	+5.22%
2013	+70.22%	+59.04%
2012	+30.00%	+51.66%
2011	-7.72%	-35.31%
2010	-20.82%	+30.91%
2009	+39.62%	+94.32%
2008	+31.23%	-60.37%
2007	-37.05%	+21.58%
2006	+34.12%	-1.66%
2005	+170.21%	+3.87%
2004	+0.67%	+21.40%
2003	-36.74%	+54.54%
2002	-35.41%	+3.94%
2001	-61.05%	+4.52%
2000	+281.33%	-19.65%
1999	+32.38%	+8.35%

VRTX vs TT Drawdown Comparison

The maximum drawdown for VRTX was -91.77%, occurring on Nov 11, 2003. Recovery took 3434 trading sessions.

The maximum drawdown for TT was -77.93%, occurring on Mar 6, 2009. Recovery took 1409 trading sessions.

The current VRTX drawdown is -16.82%. The current TT drawdown is -5.35%.

Rank	VRTX	TT
#1	-91.77% Nov 2, 2000 - Jul 2, 2014	-77.93% Jun 21, 2007 - Jan 25, 2013
#2	-55.25% Mar 6, 2000 - Jun 16, 2000	-51.11% Feb 14, 2020 - Nov 6, 2020
#3	-49.10% Aug 19, 2015 - Jul 19, 2017	-46.07% Jan 7, 2000 - Jul 21, 2003
#4	-41.60% Jul 20, 2020 - Aug 15, 2022	-40.54% Aug 3, 2021 - Aug 2, 2023
#5	-29.08% Sep 28, 2000 - Oct 25, 2000	-30.16% May 15, 2015 - Nov 7, 2016
#6	-29.07% Nov 8, 2024 - Aug 8, 2025	-25.62% May 10, 2006 - May 9, 2007
#7	-22.82% Jul 12, 2000 - Aug 16, 2000	-24.44% Nov 26, 2024 - May 13, 2025
#8	-21.18% Sep 28, 2018 - Jan 18, 2019	-19.97% Jul 28, 2025 - Feb 11, 2026
#9	-19.52% Jan 21, 2000 - Feb 7, 2000	-18.66% Mar 4, 2005 - Mar 17, 2006
#10	-19.39% Feb 11, 2020 - Apr 6, 2020	-17.86% Dec 3, 2018 - Feb 20, 2019
#11	-17.73% Mar 12, 2018 - Jul 12, 2018	-16.60% Jul 22, 2014 - Dec 19, 2014
#12	-17.36% Jul 24, 2017 - Jan 23, 2018	-16.35% Feb 1, 2018 - Jul 25, 2018
#13	-15.45% Jan 18, 2019 - Oct 29, 2019	-16.13% Apr 16, 2004 - Nov 8, 2004
#14	-15.26% Jan 22, 2015 - Mar 16, 2015	-14.31% Feb 11, 2026 - Apr 13, 2026
#15	-14.46% Jul 11, 2014 - Sep 19, 2014	-13.40% Nov 16, 1999 - Dec 28, 1999