StockComparison Logo
vs

VRTX vs ISRG

Comparison between Vertex Pharmaceuticals Inc (VRTX, Company) and Intuitive Surgical Inc (ISRG, Company).

Both VRTX and ISRG are from the Healthcare sector.

5-Year PerformanceVRTX has outperformed ISRG, delivering a return of +18.7% compared to +0.4%

VRTX vs ISRG - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap
VRTX
$120B
Winner
ISRG
$121B
Max Drawdown
VRTX
91.77%
Winner
ISRG
82.26%
Sharpe Ratio
Winner
VRTX
0.09
ISRG
-1.15
5Y Beta
Winner
VRTX
0.50
ISRG
1.14
Industry
VRTX
Biotechnology
ISRG
Medical Instruments & Supplies
P/E Ratio
Winner
VRTX
27.73
ISRG
38.48
Forward P/E
Winner
VRTX
24.94
ISRG
33.67
PEG Ratio
Winner
VRTX
1.63
ISRG
1.80
5Y EPS CAGR
VRTX
9.89%
Winner
ISRG
14.10%
Debt to Equity
VRTX
0.00%
ISRG
0.00%
Free Cash Flow Yield
Winner
VRTX
3.09%
ISRG
3.07%
P/S Ratio
Winner
VRTX
9.82
ISRG
11.06
P/B Ratio
Winner
VRTX
6.32
ISRG
6.78

VRTX vs ISRG - Historical Returns

Returns include dividend reinvestment.

1M
Winner
VRTX
+1.00%
ISRG
-17.65%
3M
Winner
VRTX
+8.73%
ISRG
-30.66%
6M
Winner
VRTX
+1.00%
ISRG
-36.64%
1Y
Winner
VRTX
-0.81%
ISRG
-33.85%
5Y(CAGR)
Winner
VRTX
+18.73%
ISRG
+0.40%
10Y(CAGR)
Winner
VRTX
+17.55%
ISRG
+15.79%
Max(CAGR)
VRTX
+14.32%
Winner
ISRG
+21.57%

VRTX vs ISRG - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

YearVRTXISRG
2026+4.64%-40.92%
2025+11.73%+8.08%
2024-2.00%+57.70%
2023+42.26%+27.00%
2022+29.77%-26.29%
2021-4.28%+34.74%
2020+7.70%+36.98%
2019+33.44%+26.85%
2018+8.37%+27.63%
2017+100.11%+70.59%
2016-40.05%+15.85%
2015+2.24%+3.92%
2014+60.91%+39.19%
2013+70.22%-22.80%
2012+30.00%+3.96%
2011-7.72%+72.12%
2010-20.82%-16.52%
2009+39.62%+129.16%
2008+31.23%-60.80%
2007-37.05%+241.87%
2006+34.12%-17.19%
2005+170.21%+210.82%
2004+0.67%+136.25%
2003-36.74%+40.08%
2002-35.41%-36.82%
2001-61.05%+22.92%
2000+281.33%-6.80%
1999+32.38%N/A

VRTX vs ISRG Drawdown Comparison

The maximum drawdown for VRTX was -91.77%, occurring on Nov 11, 2003. Recovery took 3434 trading sessions.

The maximum drawdown for ISRG was -82.26%, occurring on Apr 11, 2001. Recovery took 1103 trading sessions.

The current VRTX drawdown is -10.67%. The current ISRG drawdown is -45.61%.

RankVRTXISRG
#1-91.77%
Nov 2, 2000 - Jul 2, 2014
-82.26%
Jul 31, 2000 - Dec 21, 2004
#2-55.25%
Mar 6, 2000 - Jun 16, 2000
-75.89%
Apr 10, 2008 - Mar 1, 2010
#3-49.10%
Aug 19, 2015 - Jul 19, 2017
-49.90%
Nov 8, 2021 - Jan 18, 2024
#4-41.60%
Jul 20, 2020 - Aug 15, 2022
-45.61%
Jan 22, 2025 - Jul 23, 2026
#5-29.08%
Sep 28, 2000 - Oct 25, 2000
-40.52%
Feb 20, 2020 - Jul 17, 2020
#6-29.07%
Nov 8, 2024 - Jul 2, 2026
-40.11%
May 1, 2012 - Mar 14, 2016
#7-22.82%
Jul 12, 2000 - Aug 16, 2000
-36.54%
Jan 31, 2006 - May 30, 2007
#8-21.18%
Sep 28, 2018 - Jan 18, 2019
-36.21%
Apr 15, 2010 - Jul 20, 2011
#9-19.52%
Jan 21, 2000 - Feb 7, 2000
-33.43%
Dec 7, 2007 - Apr 10, 2008
#10-19.39%
Feb 11, 2020 - Apr 6, 2020
-24.33%
Oct 1, 2018 - Mar 21, 2019
#11-17.73%
Mar 12, 2018 - Jul 12, 2018
-22.31%
Jul 21, 2011 - Oct 19, 2011
#12-17.36%
Jul 24, 2017 - Jan 23, 2018
-21.78%
Apr 10, 2019 - Nov 26, 2019
#13-15.45%
Jan 18, 2019 - Oct 29, 2019
-21.19%
Apr 7, 2005 - Jul 11, 2005
#14-15.26%
Jan 22, 2015 - Mar 16, 2015
-19.12%
Oct 25, 2007 - Dec 5, 2007
#15-14.46%
Jul 11, 2014 - Sep 19, 2014
-18.18%
Jun 21, 2000 - Jul 10, 2000

Correlation

Correlation between VRTX and ISRG is 0.96 which considered as a very strong positive correlation - the stocks move almost identically together.

0.96
-101

Select Stocks to Compare