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TYRA vs PSNL

Comparison between Tyra Biosciences Inc (TYRA, Company) and Personalis Inc (PSNL, Company).

Both TYRA and PSNL are from the Healthcare sector.

5-Year PerformanceTYRA has outperformed PSNL, delivering a return of -0.8% compared to -4.6%

TYRA vs PSNL - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap
TYRA
$1.51B
Winner
PSNL
$1.51B
Max Drawdown
Winner
TYRA
83.22%
PSNL
98.18%
Sharpe Ratio
TYRA
1.65
Winner
PSNL
1.67
5Y Beta
Winner
TYRA
0.98
PSNL
2.20
Industry
TYRA
Biotechnology
PSNL
Diagnostics & Research
P/E Ratio
TYRA
-9.68
Winner
PSNL
-13.39
PEG Ratio
TYRA
-0.33
PSNL
N/A
5Y EPS CAGR
TYRA
N/A
PSNL
-2.57%
Debt to Equity
TYRA
0.00%
PSNL
0.00%
Free Cash Flow Yield
TYRA
-7.28%
Winner
PSNL
-6.68%

TYRA vs PSNL - Historical Returns

Returns include dividend reinvestment.

1M
TYRA
-23.42%
Winner
PSNL
-4.12%
3M
TYRA
-30.86%
Winner
PSNL
+125.67%
6M
TYRA
-10.61%
Winner
PSNL
+75.64%
1Y
TYRA
+132.74%
Winner
PSNL
+198.55%
5Y(CAGR)
Winner
TYRA
-0.78%
PSNL
-4.63%
Max(CAGR)
Winner
TYRA
-0.78%
PSNL
-9.09%

TYRA vs PSNL - Annual Returns (2019 - 2026)

Returns include dividend reinvestment.

YearTYRAPSNL
2026-6.61%+83.69%
2025+82.19%+26.95%
2024-1.00%+183.33%
2023+95.90%+4.48%
2022-46.06%-86.15%
2021-45.88%-58.97%
2020N/A+235.56%
2019N/A-61.74%

TYRA vs PSNL Drawdown Comparison

The maximum drawdown for TYRA was -83.22%, occurring on Jun 17, 2022. Recovery took 1058 trading sessions.

The maximum drawdown for PSNL was -98.18%, occurring on Oct 23, 2023. This drawdown has not yet recovered.

The current TYRA drawdown is -36.83%. The current PSNL drawdown is -71.74%.

RankTYRAPSNL
#1-83.22%
Nov 4, 2021 - Jan 27, 2026
-98.18%
Jan 20, 2021 - Oct 23, 2023
#2-48.23%
Sep 15, 2021 - Nov 3, 2021
-84.30%
Jun 21, 2019 - Oct 9, 2020
#3-36.83%
Apr 2, 2026 - Aug 13, 2026
-25.91%
Dec 22, 2020 - Jan 19, 2021
#4-13.45%
Jan 29, 2026 - Feb 23, 2026
-19.50%
Oct 9, 2020 - Nov 20, 2020
#5-9.38%
Mar 19, 2026 - Mar 31, 2026
-18.45%
Nov 20, 2020 - Dec 7, 2020
#6-5.74%
Feb 25, 2026 - Mar 4, 2026
-11.61%
Dec 10, 2020 - Dec 21, 2020
#7-4.31%
Mar 4, 2026 - Mar 11, 2026
N/A
#8-1.48%
Mar 11, 2026 - Mar 16, 2026
N/A
#9-1.02%
Jan 27, 2026 - Jan 29, 2026
N/A
#10-0.05%
Mar 31, 2026 - Apr 2, 2026
N/A

Correlation

Correlation between TYRA and PSNL is 0.46 which considered as a weak positive correlation - the stocks show a slight tendency to move together.

0.46
-101

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