TYRA vs PLAB

Comparison between Tyra Biosciences Inc (TYRA, Company) and Photronics Inc (PLAB, Company).

TYRA is from the Healthcare sector, while PLAB is from the Technology sector.

5-Year PerformancePLAB has outperformed TYRA, delivering a return of +18.4% compared to +3.6%

TYRA vs PLAB - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	TYRA(COMPANY)	PLAB(COMPANY)
Market Cap	$1.82B	$1.82B
Max Drawdown	83.22%	99.22%
Sharpe Ratio	2.01	0.93
5Y Beta	1.01	1.99
Industry	Biotechnology	Semiconductor Equipment & Materials
P/E Ratio	-12.86	11.36
Forward P/E	N/A	13.26
PEG Ratio	-0.44	0.27
5Y EPS CAGR	N/A	37.05%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-5.63%	5.30%
P/S Ratio	N/A	2.14
P/B Ratio	4.88	1.49

Market Cap

Winner

TYRA

$1.82B

PLAB

$1.82B

Max Drawdown

Winner

TYRA

83.22%

PLAB

99.22%

Sharpe Ratio

Winner

TYRA

2.01

PLAB

0.93

5Y Beta

Winner

TYRA

1.01

PLAB

1.99

Industry

TYRA

Biotechnology

PLAB

Semiconductor Equipment & Materials

P/E Ratio

Winner

TYRA

-12.86

PLAB

11.36

Forward P/E

TYRA

N/A

PLAB

13.26

PEG Ratio

Winner

TYRA

-0.44

PLAB

0.27

5Y EPS CAGR

TYRA

N/A

PLAB

37.05%

Debt to Equity

TYRA

0.00%

PLAB

0.00%

Free Cash Flow Yield

TYRA

-5.63%

Winner

PLAB

5.30%

P/S Ratio

TYRA

N/A

PLAB

2.14

P/B Ratio

TYRA

4.88

Winner

PLAB

1.49

TYRA vs PLAB - Historical Returns

Returns include dividend reinvestment.

Period	TYRA	PLAB
1 month	+2.46%	-1.93%
3 months	-16.05%	-38.71%
6 months	+1.42%	-10.87%
1 year	+184.92%	+58.42%
5 years(CAGR)	+3.55%	+18.38%
10 years(CAGR)	N/A	+12.58%
Max(CAGR)	+3.55%	+1.43%

Winner

TYRA

+2.46%

PLAB

-1.93%

Winner

TYRA

-16.05%

PLAB

-38.71%

Winner

TYRA

+1.42%

PLAB

-10.87%

Winner

TYRA

+184.92%

PLAB

+58.42%

5Y(CAGR)

TYRA

+3.55%

Winner

PLAB

+18.38%

10Y(CAGR)

TYRA

N/A

PLAB

+12.58%

Max(CAGR)

Winner

TYRA

+3.55%

PLAB

+1.43%

TYRA vs PLAB - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	TYRA	PLAB
2026	+14.97%	-7.39%
2025	+82.19%	+33.28%
2024	-1.00%	-23.66%
2023	+95.90%	+87.17%
2022	-46.06%	-12.71%
2021	-45.88%	+71.83%
2020	N/A	-28.37%
2019	N/A	+61.15%
2018	N/A	+12.56%
2017	N/A	-24.89%
2016	N/A	-6.84%
2015	N/A	+52.39%
2014	N/A	-6.52%
2013	N/A	+49.50%
2012	N/A	-2.93%
2011	N/A	+1.93%
2010	N/A	+27.92%
2009	N/A	+117.07%
2008	N/A	-84.16%
2007	N/A	-23.02%
2006	N/A	+8.14%
2005	N/A	-5.34%
2004	N/A	-17.21%
2003	N/A	+37.38%
2002	N/A	-57.81%
2001	N/A	+39.33%
2000	N/A	-16.46%
1999	N/A	+35.11%

TYRA vs PLAB Drawdown Comparison

The maximum drawdown for TYRA was -83.22%, occurring on Jun 17, 2022. Recovery took 1058 trading sessions.

The maximum drawdown for PLAB was -99.22%, occurring on Nov 25, 2008. Recovery took 6564 trading sessions.

The current TYRA drawdown is -22.24%. The current PLAB drawdown is -43.70%.

Rank	TYRA	PLAB
#1	-83.22% Nov 4, 2021 - Jan 27, 2026	-99.22% Mar 6, 2000 - Apr 13, 2026
#2	-48.23% Sep 15, 2021 - Nov 3, 2021	-49.87% May 11, 2026 - Jul 7, 2026
#3	-35.82% Apr 2, 2026 - Jun 10, 2026	-12.91% Jan 20, 2000 - Feb 16, 2000
#4	-13.45% Jan 29, 2026 - Feb 23, 2026	-12.64% Dec 29, 1999 - Jan 18, 2000
#5	-9.38% Mar 19, 2026 - Mar 31, 2026	-11.73% Nov 19, 1999 - Dec 21, 1999
#6	-5.74% Feb 25, 2026 - Mar 4, 2026	-10.05% Nov 1, 1999 - Nov 10, 1999
#7	-4.31% Mar 4, 2026 - Mar 11, 2026	-9.64% Feb 17, 2000 - Feb 29, 2000
#8	-1.48% Mar 11, 2026 - Mar 16, 2026	-8.61% Apr 24, 2026 - May 8, 2026
#9	-1.02% Jan 27, 2026 - Jan 29, 2026	-3.61% Dec 21, 1999 - Dec 28, 1999
#10	-0.05% Mar 31, 2026 - Apr 2, 2026	-1.76% Feb 29, 2000 - Mar 3, 2000
#11	N/A	-0.55% Nov 12, 1999 - Nov 17, 1999
#12	N/A	-0.28% Nov 17, 1999 - Nov 19, 1999
#13	N/A	-0.04% Apr 15, 2026 - Apr 17, 2026