TYRA vs DVAX

Comparison between Tyra Biosciences Inc (TYRA, Company) and Dynavax Technologies Corp (DVAX, Company).

Both TYRA and DVAX are from the Healthcare sector.

5-Year PerformanceDVAX has outperformed TYRA, delivering a return of +10.2% compared to +3.6%

TYRA vs DVAX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	TYRA(COMPANY)	DVAX(COMPANY)
Market Cap	$1.82B	$1.82B
Max Drawdown	83.22%	98.47%
Sharpe Ratio	2.01	0.47
5Y Beta	1.01	N/A
Industry	Biotechnology	Drug Manufacturers - Specialty & Generic
P/E Ratio	-12.86	-46.75
Forward P/E	N/A	29.24
PEG Ratio	-0.44	N/A
5Y EPS CAGR	N/A	-20.02%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-5.63%	4.43%
P/B Ratio	4.88	N/A

Market Cap

Winner

TYRA

$1.82B

DVAX

$1.82B

Max Drawdown

Winner

TYRA

83.22%

DVAX

98.47%

Sharpe Ratio

Winner

TYRA

2.01

DVAX

0.47

5Y Beta

TYRA

1.01

DVAX

N/A

Industry

TYRA

Biotechnology

DVAX

Drug Manufacturers - Specialty & Generic

P/E Ratio

TYRA

-12.86

Winner

DVAX

-46.75

Forward P/E

TYRA

N/A

DVAX

29.24

PEG Ratio

TYRA

-0.44

DVAX

N/A

5Y EPS CAGR

TYRA

N/A

DVAX

-20.02%

Debt to Equity

TYRA

0.00%

DVAX

0.00%

Free Cash Flow Yield

TYRA

-5.63%

Winner

DVAX

4.43%

P/B Ratio

TYRA

4.88

DVAX

N/A

TYRA vs DVAX - Historical Returns

Returns include dividend reinvestment.

Period	TYRA	DVAX
1 month	+2.46%	-1.15%
3 months	-16.05%	+37.53%
6 months	+1.42%	+47.97%
1 year	+184.92%	+22.05%
5 years(CAGR)	+3.55%	+10.22%
10 years(CAGR)	N/A	-1.97%
Max(CAGR)	+3.55%	-7.87%

Winner

TYRA

+2.46%

DVAX

-1.15%

TYRA

-16.05%

Winner

DVAX

+37.53%

TYRA

+1.42%

Winner

DVAX

+47.97%

Winner

TYRA

+184.92%

DVAX

+22.05%

5Y(CAGR)

TYRA

+3.55%

Winner

DVAX

+10.22%

10Y(CAGR)

TYRA

N/A

DVAX

-1.97%

Max(CAGR)

Winner

TYRA

+3.55%

DVAX

-7.87%

TYRA vs DVAX - Annual Returns (2004 - 2026)

Returns include dividend reinvestment.

Year	TYRA	DVAX
2026	+14.97%	+0.78%
2025	+82.19%	+19.22%
2024	-1.00%	-11.20%
2023	+95.90%	+31.89%
2022	-46.06%	-23.34%
2021	-45.88%	+204.55%
2020	N/A	-18.65%
2019	N/A	-39.47%
2018	N/A	-51.33%
2017	N/A	+361.73%
2016	N/A	-82.94%
2015	N/A	+38.77%
2014	N/A	-15.28%
2013	N/A	-32.88%
2012	N/A	-13.11%
2011	N/A	+7.44%
2010	N/A	+122.22%
2009	N/A	+79.77%
2008	N/A	-84.00%
2007	N/A	-39.67%
2006	N/A	+113.99%
2005	N/A	-45.96%
2004	N/A	-14.89%

TYRA vs DVAX Drawdown Comparison

The maximum drawdown for TYRA was -83.22%, occurring on Jun 17, 2022. Recovery took 1058 trading sessions.

The maximum drawdown for DVAX was -98.47%, occurring on Nov 20, 2008. This drawdown has not yet recovered.

The current TYRA drawdown is -22.24%. The current DVAX drawdown is -84.26%.

Rank	TYRA	DVAX
#1	-83.22% Nov 4, 2021 - Jan 27, 2026	-98.47% Dec 11, 2006 - Nov 20, 2008
#2	-48.23% Sep 15, 2021 - Nov 3, 2021	-61.81% Feb 19, 2004 - Nov 29, 2006
#3	-35.82% Apr 2, 2026 - Jun 10, 2026	-7.25% Nov 29, 2006 - Dec 11, 2006
#4	-13.45% Jan 29, 2026 - Feb 23, 2026	N/A
#5	-9.38% Mar 19, 2026 - Mar 31, 2026	N/A
#6	-5.74% Feb 25, 2026 - Mar 4, 2026	N/A
#7	-4.31% Mar 4, 2026 - Mar 11, 2026	N/A
#8	-1.48% Mar 11, 2026 - Mar 16, 2026	N/A
#9	-1.02% Jan 27, 2026 - Jan 29, 2026	N/A
#10	-0.05% Mar 31, 2026 - Apr 2, 2026	N/A