TYRA vs CNXN

Comparison between Tyra Biosciences Inc (TYRA, Company) and PC Connection Inc (CNXN, Company).

TYRA is from the Healthcare sector, while CNXN is from the Technology sector.

5-Year PerformanceCNXN has outperformed TYRA, delivering a return of +14.2% compared to +4.3%

TYRA vs CNXN - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	TYRA(COMPANY)	CNXN(COMPANY)
Market Cap	$1.93B	$1.92B
Max Drawdown	83.22%	95.90%
Sharpe Ratio	2.02	0.85
5Y Beta	1.02	0.69
Industry	Biotechnology	Electronics & Computer Distribution
P/E Ratio	-13.61	24.13
Forward P/E	N/A	20.83
PEG Ratio	-0.47	2.07
Dividend Yield	N/A	0.82%
5Y Dividends CAGR	N/A	21.58%
5Y EPS CAGR	N/A	4.11%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-5.32%	6.49%
P/S Ratio	N/A	0.68
P/B Ratio	5.03	2.15

Market Cap

Winner

TYRA

$1.93B

CNXN

$1.92B

Max Drawdown

Winner

TYRA

83.22%

CNXN

95.90%

Sharpe Ratio

Winner

TYRA

2.02

CNXN

0.85

5Y Beta

TYRA

1.02

Winner

CNXN

0.69

Industry

TYRA

Biotechnology

CNXN

Electronics & Computer Distribution

P/E Ratio

Winner

TYRA

-13.61

CNXN

24.13

Forward P/E

TYRA

N/A

CNXN

20.83

PEG Ratio

Winner

TYRA

-0.47

CNXN

2.07

Dividend Yield

TYRA

N/A

CNXN

0.82%

5Y Dividends CAGR

TYRA

N/A

CNXN

21.58%

5Y EPS CAGR

TYRA

N/A

CNXN

4.11%

Debt to Equity

TYRA

0.00%

CNXN

0.00%

Free Cash Flow Yield

TYRA

-5.32%

Winner

CNXN

6.49%

P/S Ratio

TYRA

N/A

CNXN

0.68

P/B Ratio

TYRA

5.03

Winner

CNXN

2.15

TYRA vs CNXN - Historical Returns

Returns include dividend reinvestment.

Period	TYRA	CNXN
1 month	+5.67%	+17.22%
3 months	-13.19%	+26.61%
6 months	+8.22%	+41.71%
1 year	+200.19%	+25.85%
5 years(CAGR)	+4.28%	+14.25%
10 years(CAGR)	N/A	+13.65%
Max(CAGR)	+4.28%	+7.39%

TYRA

+5.67%

Winner

CNXN

+17.22%

TYRA

-13.19%

Winner

CNXN

+26.61%

TYRA

+8.22%

Winner

CNXN

+41.71%

Winner

TYRA

+200.19%

CNXN

+25.85%

5Y(CAGR)

TYRA

+4.28%

Winner

CNXN

+14.25%

10Y(CAGR)

TYRA

N/A

CNXN

+13.65%

Max(CAGR)

TYRA

+4.28%

Winner

CNXN

+7.39%

TYRA vs CNXN - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	TYRA	CNXN
2026	+18.89%	+43.70%
2025	+82.19%	-15.21%
2024	-1.00%	+6.37%
2023	+95.90%	+34.54%
2022	-46.06%	+8.49%
2021	-45.88%	-5.58%
2020	N/A	-5.08%
2019	N/A	+64.91%
2018	N/A	+14.38%
2017	N/A	-4.47%
2016	N/A	+28.08%
2015	N/A	-4.32%
2014	N/A	+2.76%
2013	N/A	+121.61%
2012	N/A	-1.08%
2011	N/A	+28.82%
2010	N/A	+20.71%
2009	N/A	+38.32%
2008	N/A	-54.61%
2007	N/A	-26.49%
2006	N/A	+174.63%
2005	N/A	-43.55%
2004	N/A	+13.47%
2003	N/A	+65.49%
2002	N/A	-64.72%
2001	N/A	+49.23%
2000	N/A	-52.82%
1999	N/A	+51.25%

TYRA vs CNXN Drawdown Comparison

The maximum drawdown for TYRA was -83.22%, occurring on Jun 17, 2022. Recovery took 1058 trading sessions.

The maximum drawdown for CNXN was -95.90%, occurring on Mar 11, 2009. Recovery took 5825 trading sessions.

The current TYRA drawdown is -19.59%.

Rank	TYRA	CNXN
#1	-83.22% Nov 4, 2021 - Jan 27, 2026	-95.90% Sep 7, 2000 - Nov 2, 2023
#2	-48.23% Sep 15, 2021 - Nov 3, 2021	-36.06% Dec 31, 1999 - Apr 19, 2000
#3	-35.82% Apr 2, 2026 - Jun 10, 2026	-26.89% Jul 6, 2000 - Aug 31, 2000
#4	-13.45% Jan 29, 2026 - Feb 23, 2026	-26.27% Sep 26, 2024 - Jul 9, 2026
#5	-9.38% Mar 19, 2026 - Mar 31, 2026	-16.22% May 1, 2000 - May 30, 2000
#6	-5.74% Feb 25, 2026 - Mar 4, 2026	-14.68% Feb 15, 2024 - Jul 30, 2024
#7	-4.31% Mar 4, 2026 - Mar 11, 2026	-11.25% Aug 1, 2024 - Sep 19, 2024
#8	-1.48% Mar 11, 2026 - Mar 16, 2026	-10.71% Nov 8, 1999 - Dec 1, 1999
#9	-1.02% Jan 27, 2026 - Jan 29, 2026	-9.38% Dec 13, 1999 - Dec 29, 1999
#10	-0.05% Mar 31, 2026 - Apr 2, 2026	-8.20% Dec 26, 2023 - Feb 15, 2024
#11	N/A	-7.62% Jun 14, 2000 - Jun 27, 2000
#12	N/A	-6.64% Apr 20, 2000 - Apr 25, 2000
#13	N/A	-5.68% Apr 25, 2000 - Apr 27, 2000
#14	N/A	-5.54% Dec 2, 1999 - Dec 10, 1999
#15	N/A	-4.04% Jun 2, 2000 - Jun 8, 2000