TYRA vs CHCO

Comparison between Tyra Biosciences Inc (TYRA, Company) and City Holding Company (CHCO, Company).

TYRA is from the Healthcare sector, while CHCO is from the Financial Services sector.

5-Year PerformanceCHCO has outperformed TYRA, delivering a return of +16.1% compared to +4.3%

TYRA vs CHCO - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	TYRA(COMPANY)	CHCO(COMPANY)
Market Cap	$1.93B	$1.92B
Max Drawdown	83.22%	72.22%
Sharpe Ratio	2.02	0.44
5Y Beta	1.02	0.52
Industry	Biotechnology	Banks - Regional
P/E Ratio	-13.61	14.86
Forward P/E	N/A	16.42
PEG Ratio	-0.47	1.16
Dividend Yield	N/A	2.50%
5Y Dividends CAGR	N/A	13.07%
5Y EPS CAGR	N/A	10.79%
Debt to Equity	0.00%	18.88%
Free Cash Flow Yield	-5.32%	7.01%
P/S Ratio	N/A	5.92
P/B Ratio	5.03	2.38

Market Cap

Winner

TYRA

$1.93B

CHCO

$1.92B

Max Drawdown

TYRA

83.22%

Winner

CHCO

72.22%

Sharpe Ratio

Winner

TYRA

2.02

CHCO

0.44

5Y Beta

TYRA

1.02

Winner

CHCO

0.52

Industry

TYRA

Biotechnology

CHCO

Banks - Regional

P/E Ratio

Winner

TYRA

-13.61

CHCO

14.86

Forward P/E

TYRA

N/A

CHCO

16.42

PEG Ratio

Winner

TYRA

-0.47

CHCO

1.16

Dividend Yield

TYRA

N/A

CHCO

2.50%

5Y Dividends CAGR

TYRA

N/A

CHCO

13.07%

5Y EPS CAGR

TYRA

N/A

CHCO

10.79%

Debt to Equity

Winner

TYRA

0.00%

CHCO

18.88%

Free Cash Flow Yield

TYRA

-5.32%

Winner

CHCO

7.01%

P/S Ratio

TYRA

N/A

CHCO

5.92

P/B Ratio

TYRA

5.03

Winner

CHCO

2.38

TYRA vs CHCO - Historical Returns

Returns include dividend reinvestment.

Period	TYRA	CHCO
1 month	+5.67%	+6.29%
3 months	-13.19%	+8.40%
6 months	+8.22%	+10.09%
1 year	+200.19%	+11.85%
5 years(CAGR)	+4.28%	+16.07%
10 years(CAGR)	N/A	+14.52%
Max(CAGR)	+4.28%	+11.91%

TYRA

+5.67%

Winner

CHCO

+6.29%

TYRA

-13.19%

Winner

CHCO

+8.40%

TYRA

+8.22%

Winner

CHCO

+10.09%

Winner

TYRA

+200.19%

CHCO

+11.85%

5Y(CAGR)

TYRA

+4.28%

Winner

CHCO

+16.07%

10Y(CAGR)

TYRA

N/A

CHCO

+14.52%

Max(CAGR)

TYRA

+4.28%

Winner

CHCO

+11.91%

TYRA vs CHCO - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	TYRA	CHCO
2026	+18.89%	+14.91%
2025	+82.19%	+4.39%
2024	-1.00%	+9.25%
2023	+95.90%	+22.58%
2022	-46.06%	+16.34%
2021	-45.88%	+22.12%
2020	N/A	-12.48%
2019	N/A	+24.18%
2018	N/A	+3.70%
2017	N/A	+2.83%
2016	N/A	+58.30%
2015	N/A	+2.95%
2014	N/A	+5.39%
2013	N/A	+31.96%
2012	N/A	+4.19%
2011	N/A	-5.12%
2010	N/A	+15.43%
2009	N/A	+1.19%
2008	N/A	+8.98%
2007	N/A	-14.78%
2006	N/A	+14.75%
2005	N/A	+3.62%
2004	N/A	+4.89%
2003	N/A	+27.67%
2002	N/A	+129.67%
2001	N/A	+109.39%
2000	N/A	-56.95%
1999	N/A	-8.59%

TYRA vs CHCO Drawdown Comparison

The maximum drawdown for TYRA was -83.22%, occurring on Jun 17, 2022. Recovery took 1058 trading sessions.

The maximum drawdown for CHCO was -70.53%, occurring on Dec 22, 2000. Recovery took 592 trading sessions.

The current TYRA drawdown is -19.59%. The current CHCO drawdown is -1.97%.

Rank	TYRA	CHCO
#1	-83.22% Nov 4, 2021 - Jan 27, 2026	-70.53% Nov 26, 1999 - Apr 10, 2002
#2	-48.23% Sep 15, 2021 - Nov 3, 2021	-54.95% Sep 19, 2008 - Mar 15, 2013
#3	-35.82% Apr 2, 2026 - Jun 10, 2026	-32.25% Dec 23, 2019 - Mar 5, 2021
#4	-13.45% Jan 29, 2026 - Feb 23, 2026	-24.68% Dec 1, 2004 - Jul 5, 2005
#5	-9.38% Mar 19, 2026 - Mar 31, 2026	-24.04% Dec 30, 2003 - Nov 11, 2004
#6	-5.74% Feb 25, 2026 - Mar 4, 2026	-23.82% Dec 27, 2006 - Mar 20, 2008
#7	-4.31% Mar 4, 2026 - Mar 11, 2026	-20.51% Aug 19, 2002 - Oct 30, 2002
#8	-1.48% Mar 11, 2026 - Mar 16, 2026	-19.61% Jul 15, 2015 - Aug 25, 2016
#9	-1.02% Jan 27, 2026 - Jan 29, 2026	-19.26% Aug 22, 2018 - Apr 17, 2019
#10	-0.05% Mar 31, 2026 - Apr 2, 2026	-18.38% Nov 11, 2024 - Jul 23, 2025
#11	N/A	-18.34% May 27, 2008 - Jul 29, 2008
#12	N/A	-17.09% Apr 26, 2017 - Oct 2, 2017
#13	N/A	-16.86% Oct 24, 2022 - Dec 1, 2023
#14	N/A	-16.04% Mar 12, 2021 - Jan 6, 2022
#15	N/A	-14.38% May 8, 2002 - Jun 21, 2002