TVTX vs APLS

Comparison between Travere Therapeutics Inc (TVTX, Company) and Apellis Pharmaceuticals Inc (APLS, Company).

Both TVTX and APLS are from the Healthcare sector.

5-Year PerformanceTVTX has outperformed APLS, delivering a return of +32.7% compared to -1.5%

TVTX vs APLS - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	TVTX(COMPANY)	APLS(COMPANY)
Market Cap	$5.24B	$5.25B
Max Drawdown	85.43%	82.47%
Sharpe Ratio	2.05	1.03
5Y Beta	1.28	N/A
Industry	Biotechnology	Biotechnology
P/E Ratio	-249.63	39.02
Forward P/E	77.52	46.30
5Y EPS CAGR	-44.12%	N/A
Debt to Equity	0.00%	22.59%
Free Cash Flow Yield	0.74%	0.71%
P/S Ratio	9.84	N/A
P/B Ratio	53.75	N/A

Market Cap

TVTX

$5.24B

Winner

APLS

$5.25B

Max Drawdown

TVTX

85.43%

Winner

APLS

82.47%

Sharpe Ratio

Winner

TVTX

2.05

APLS

1.03

5Y Beta

TVTX

1.28

APLS

N/A

Industry

TVTX

Biotechnology

APLS

Biotechnology

P/E Ratio

Winner

TVTX

-249.63

APLS

39.02

Forward P/E

TVTX

77.52

Winner

APLS

46.30

5Y EPS CAGR

TVTX

-44.12%

APLS

N/A

Debt to Equity

Winner

TVTX

0.00%

APLS

22.59%

Free Cash Flow Yield

Winner

TVTX

0.74%

APLS

0.71%

P/S Ratio

TVTX

9.84

APLS

N/A

P/B Ratio

TVTX

53.75

APLS

N/A

TVTX vs APLS - Historical Returns

Returns include dividend reinvestment.

Period	TVTX	APLS
1 month	+2.67%	+0.44%
3 months	+45.90%	+89.08%
6 months	+100.28%	+101.82%
1 year	+257.65%	+145.69%
5 years(CAGR)	+32.72%	-1.50%
10 years(CAGR)	+12.28%	+13.44%
Max(CAGR)	+30.35%	+13.44%

Winner

TVTX

+2.67%

APLS

+0.44%

TVTX

+45.90%

Winner

APLS

+89.08%

TVTX

+100.28%

Winner

APLS

+101.82%

Winner

TVTX

+257.65%

APLS

+145.69%

5Y(CAGR)

Winner

TVTX

+32.72%

APLS

-1.50%

10Y(CAGR)

TVTX

+12.28%

Winner

APLS

+13.44%

Max(CAGR)

Winner

TVTX

+30.35%

APLS

+13.44%

TVTX vs APLS - Annual Returns (2012 - 2026)

Returns include dividend reinvestment.

Year	TVTX	APLS
2026	+43.17%	+58.66%
2025	+101.42%	-24.25%
2024	+82.22%	-47.92%
2023	-56.49%	+19.05%
2022	-31.27%	+6.03%
2021	+14.96%	-13.39%
2020	+96.50%	+83.54%
2019	-37.36%	+124.82%
2018	+0.71%	-36.53%
2017	+14.20%	+54.67%
2016	+0.21%	N/A
2015	+52.25%	N/A
2014	+53.00%	N/A
2013	+118.75%	N/A
2012	+123.33%	N/A

TVTX vs APLS Drawdown Comparison

The maximum drawdown for TVTX was -85.43%, occurring on Apr 26, 2024. Recovery took 2583 trading sessions.

The maximum drawdown for APLS was -82.47%, occurring on May 15, 2025. This drawdown has not yet recovered.

The current TVTX drawdown is -4.15%. The current APLS drawdown is -56.03%.

Rank	TVTX	APLS
#1	-85.43% Aug 5, 2015 - Nov 11, 2025	-82.47% Jun 13, 2023 - May 15, 2025
#2	-65.37% Apr 2, 2014 - Mar 30, 2015	-61.77% Apr 16, 2018 - Sep 5, 2019
#3	-62.29% Dec 17, 2012 - May 3, 2013	-59.60% Feb 10, 2020 - Nov 20, 2020
#4	-48.63% May 10, 2013 - Jan 10, 2014	-55.99% Jul 2, 2021 - Apr 3, 2023
#5	-46.81% Dec 3, 2012 - Dec 17, 2012	-43.83% Jan 4, 2018 - Mar 14, 2018
#6	-33.49% Dec 24, 2025 - Apr 14, 2026	-31.32% Sep 6, 2019 - Jan 7, 2020
#7	-25.27% Jan 17, 2014 - Feb 13, 2014	-28.91% Jan 8, 2021 - Jun 1, 2021
#8	-12.97% Apr 24, 2015 - May 15, 2015	-21.52% Mar 16, 2018 - Apr 11, 2018
#9	-12.42% Mar 10, 2014 - Mar 25, 2014	-12.47% Dec 11, 2017 - Dec 21, 2017
#10	-11.81% Jul 16, 2015 - Aug 5, 2015	-8.62% May 5, 2023 - Jun 13, 2023
#11	-10.05% May 27, 2026 - Jun 9, 2026	-8.38% Dec 8, 2020 - Dec 15, 2020
#12	-9.24% Feb 21, 2014 - Mar 10, 2014	-8.03% Jun 14, 2021 - Jul 1, 2021
#13	-8.04% Jun 5, 2015 - Jun 18, 2015	-6.75% Apr 24, 2023 - May 5, 2023
#14	-7.95% Apr 14, 2026 - May 1, 2026	-6.20% Jan 21, 2020 - Feb 3, 2020
#15	-7.37% Feb 13, 2014 - Feb 20, 2014	-5.53% Nov 13, 2017 - Dec 8, 2017