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TLPH vs SPY

Comparison between Talphera Inc (TLPH, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).

5-Year PerformanceSPY has outperformed TLPH, delivering a return of +13.8% compared to -49.8%

TLPH vs SPY - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap / Net Assets
TLPH
$40M
Winner
SPY
$784B
Expense Ratio
TLPH
N/A
SPY
0.09%
Max Drawdown
TLPH
99.85%
Winner
SPY
56.47%
Sharpe Ratio
TLPH
0.96
Winner
SPY
1.56
5Y Beta
Winner
TLPH
0.72
SPY
1.00
Industry
TLPH
Drug Manufacturers - Specialty & Generic
SPY
N/A
P/E Ratio
Winner
TLPH
-2.05
SPY
28.29
Forward P/E
Winner
TLPH
1.02
SPY
21.75
5Y Dividends CAGR
TLPH
N/A
SPY
5.43%
5Y EPS CAGR
TLPH
-41.25%
Winner
SPY
25.98%
Debt to Equity
Winner
TLPH
0.00%
SPY
30.79%
Free Cash Flow Yield
TLPH
-27.92%
SPY
N/A
P/S Ratio
TLPH
41950.49
Winner
SPY
3.79
P/B Ratio
Winner
TLPH
2.26
SPY
5.67

TLPH vs SPY - Historical Returns

Returns include dividend reinvestment.

1M
Winner
TLPH
+4.40%
SPY
+2.12%
3M
TLPH
+11.71%
Winner
SPY
+13.14%
6M
TLPH
-24.97%
Winner
SPY
+11.52%
1Y
Winner
TLPH
+84.05%
SPY
+26.68%
5Y(CAGR)
TLPH
-49.82%
Winner
SPY
+13.75%
10Y(CAGR)
TLPH
-34.41%
Winner
SPY
+15.65%
Max(CAGR)
TLPH
-26.07%
Winner
SPY
+8.56%

TLPH vs SPY - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

YearTLPHSPY
2026-23.68%+10.80%
2025+93.19%+18.00%
2024-29.21%+25.59%
2023-66.89%+26.72%
2022-81.32%-18.64%
2021-55.18%+30.52%
2020-40.10%+17.28%
2019-14.92%+31.09%
2018+12.68%-5.24%
2017-20.39%+20.78%
2016-31.49%+13.59%
2015-43.47%+1.31%
2014-42.33%+14.56%
2013+146.41%+29.00%
2012+120.73%+14.17%
2011-57.80%+0.85%
2010N/A+13.14%
2009N/A+22.67%
2008N/A-36.25%
2007N/A+5.32%
2006N/A+13.85%
2005N/A+5.32%
2004N/A+10.75%
2003N/A+24.18%
2002N/A-22.42%
2001N/A-10.13%
2000N/A-8.84%
1999N/A+8.61%

TLPH vs SPY Drawdown Comparison

The maximum drawdown for TLPH was -99.85%, occurring on Aug 7, 2025. This drawdown has not yet recovered.

The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.

The current TLPH drawdown is -99.66%. The current SPY drawdown is -0.62%.

RankTLPHSPY
#1-99.85%
Jul 22, 2013 - Aug 7, 2025
-55.20%
Oct 9, 2007 - Aug 16, 2012
#2-60.00%
May 31, 2011 - Nov 26, 2012
-47.50%
Mar 24, 2000 - Oct 26, 2006
#3-33.63%
Feb 11, 2011 - May 27, 2011
-33.70%
Feb 19, 2020 - Aug 10, 2020
#4-33.40%
Nov 26, 2012 - Jan 18, 2013
-24.50%
Jan 3, 2022 - Dec 13, 2023
#5-21.97%
Feb 13, 2013 - Apr 11, 2013
-19.34%
Sep 20, 2018 - Apr 12, 2019
#6-15.90%
Jun 11, 2013 - Jul 2, 2013
-18.76%
Feb 19, 2025 - Jun 26, 2025
#7-10.99%
May 16, 2013 - May 22, 2013
-13.02%
Jul 20, 2015 - Apr 18, 2016
#8-9.84%
Jan 22, 2013 - Feb 13, 2013
-10.10%
Jan 26, 2018 - Aug 6, 2018
#9-9.76%
Apr 23, 2013 - May 7, 2013
-9.44%
Sep 2, 2020 - Nov 11, 2020
#10-9.29%
Apr 12, 2013 - Apr 23, 2013
-9.30%
Jan 19, 2000 - Mar 17, 2000
#11-8.49%
May 30, 2013 - Jun 10, 2013
-9.05%
Jul 19, 2007 - Oct 5, 2007
#12-6.94%
May 7, 2013 - May 14, 2013
-8.88%
Jan 27, 2026 - Apr 14, 2026
#13-6.36%
Jul 11, 2013 - Jul 22, 2013
-8.41%
Jul 16, 2024 - Sep 19, 2024
#14-4.27%
Jul 2, 2013 - Jul 8, 2013
-7.35%
Sep 14, 2012 - Jan 2, 2013
#15-3.34%
Jul 8, 2013 - Jul 10, 2013
-7.27%
Sep 18, 2014 - Oct 31, 2014

Correlation

Correlation between TLPH and SPY is -0.69 which considered as a moderate negative correlation - the stocks show some tendency to move in opposite directions.

-0.69
-101

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