TLPH vs GLTO

Comparison between Talphera Inc (TLPH, Company) and Galecto Inc (GLTO, Company).

Both TLPH and GLTO are from the Healthcare sector.

5-Year PerformanceGLTO has outperformed TLPH, delivering a return of -29.7% compared to -48.1%

TLPH vs GLTO - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	TLPH(COMPANY)	GLTO(COMPANY)
Market Cap	$53M	$53M
Max Drawdown	99.85%	99.47%
Sharpe Ratio	1.33	1.30
5Y Beta	0.72	N/A
Industry	Drug Manufacturers - Specialty & Generic	Biotechnology
P/E Ratio	-2.68	-0.15
Forward P/E	1.02	N/A
PEG Ratio	N/A	-0.00
5Y EPS CAGR	-41.25%	N/A
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-21.29%	-46.89%

Market Cap

TLPH

$53M

Winner

GLTO

$53M

Max Drawdown

TLPH

99.85%

Winner

GLTO

99.47%

Sharpe Ratio

Winner

TLPH

1.33

GLTO

1.30

5Y Beta

TLPH

0.72

GLTO

N/A

Industry

TLPH

Drug Manufacturers - Specialty & Generic

GLTO

Biotechnology

P/E Ratio

Winner

TLPH

-2.68

GLTO

-0.15

Forward P/E

TLPH

1.02

GLTO

N/A

PEG Ratio

TLPH

N/A

GLTO

-0.00

5Y EPS CAGR

TLPH

-41.25%

GLTO

N/A

Debt to Equity

TLPH

0.00%

GLTO

0.00%

Free Cash Flow Yield

Winner

TLPH

-21.29%

GLTO

-46.89%

TLPH vs GLTO - Historical Returns

Returns include dividend reinvestment.

Period	TLPH	GLTO
1 month	+33.75%	-12.82%
3 months	+34.35%	-9.90%
6 months	-5.31%	-23.47%
1 year	+139.37%	+558.02%
5 years(CAGR)	-48.10%	-29.68%
10 years(CAGR)	-32.10%	N/A
Max(CAGR)	-25.11%	-39.17%

Winner

TLPH

+33.75%

GLTO

-12.82%

Winner

TLPH

+34.35%

GLTO

-9.90%

Winner

TLPH

-5.31%

GLTO

-23.47%

TLPH

+139.37%

Winner

GLTO

+558.02%

5Y(CAGR)

TLPH

-48.10%

Winner

GLTO

-29.68%

10Y(CAGR)

TLPH

-32.10%

GLTO

N/A

Max(CAGR)

Winner

TLPH

-25.11%

GLTO

-39.17%

TLPH vs GLTO - Annual Returns (2011 - 2026)

Returns include dividend reinvestment.

Year	TLPH	GLTO
2026	-7.76%	+3.44%
2025	+93.19%	+303.68%
2024	-29.21%	-73.97%
2023	-66.89%	-40.50%
2022	-81.32%	-64.51%
2021	-55.18%	-76.69%
2020	-40.10%	-16.60%
2019	-14.92%	N/A
2018	+12.68%	N/A
2017	-20.39%	N/A
2016	-31.49%	N/A
2015	-43.47%	N/A
2014	-42.33%	N/A
2013	+146.41%	N/A
2012	+120.73%	N/A
2011	-57.80%	N/A

TLPH vs GLTO Drawdown Comparison

The maximum drawdown for TLPH was -99.85%, occurring on Aug 7, 2025. This drawdown has not yet recovered.

The maximum drawdown for GLTO was -99.47%, occurring on Apr 10, 2025. This drawdown has not yet recovered.

The current TLPH drawdown is -99.59%. The current GLTO drawdown is -94.64%.

Rank	TLPH	GLTO
#1	-99.85% Jul 22, 2013 - Aug 7, 2025	-99.47% Nov 23, 2020 - Apr 10, 2025
#2	-60.00% May 31, 2011 - Nov 26, 2012	-4.74% Nov 16, 2020 - Nov 23, 2020
#3	-33.63% Feb 11, 2011 - May 27, 2011	-2.99% Nov 3, 2020 - Nov 6, 2020
#4	-33.40% Nov 26, 2012 - Jan 18, 2013	-0.46% Nov 6, 2020 - Nov 11, 2020
#5	-21.97% Feb 13, 2013 - Apr 11, 2013	N/A
#6	-15.90% Jun 11, 2013 - Jul 2, 2013	N/A
#7	-10.99% May 16, 2013 - May 22, 2013	N/A
#8	-9.84% Jan 22, 2013 - Feb 13, 2013	N/A
#9	-9.76% Apr 23, 2013 - May 7, 2013	N/A
#10	-9.29% Apr 12, 2013 - Apr 23, 2013	N/A
#11	-8.49% May 30, 2013 - Jun 10, 2013	N/A
#12	-6.94% May 7, 2013 - May 14, 2013	N/A
#13	-6.36% Jul 11, 2013 - Jul 22, 2013	N/A
#14	-4.27% Jul 2, 2013 - Jul 8, 2013	N/A
#15	-3.34% Jul 8, 2013 - Jul 10, 2013	N/A