SYRE vs LB
Comparison between Spyre Therapeutics Inc (SYRE, Company) and Landbridge Company LLC. - Class A (LB, Company).
SYRE is from the Healthcare sector, while LB is from the Energy sector.
SYRE vs LB - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Market Cap
Winner
SYRE
$5.72B
LB
$5.70B
Max Drawdown
SYRE
99.11%
Winner
LB
48.33%
Sharpe Ratio
Winner
SYRE
2.47
LB
0.21
5Y Beta
SYRE
1.74
Winner
LB
1.40
Industry
SYRE
Biotechnology
LB
Oil & Gas Equipment & Services
P/E Ratio
Winner
SYRE
-29.38
LB
165.45
Forward P/E
SYRE
N/A
LB
21.60
Dividend Yield
SYRE
N/A
LB
0.57%
5Y EPS CAGR
SYRE
-2.15%
LB
N/A
Debt to Equity
Winner
SYRE
0.00%
LB
0.20%
Free Cash Flow Yield
SYRE
-3.25%
Winner
LB
2.03%
P/S Ratio
SYRE
650.22
Winner
LB
33.13
P/B Ratio
SYRE
12.16
Winner
LB
5.38
SYRE vs LB - Historical Returns
Returns include dividend reinvestment.
1M
SYRE
+3.72%
Winner
LB
+6.33%
3M
Winner
SYRE
+81.45%
LB
-5.66%
6M
Winner
SYRE
+120.18%
LB
+18.22%
1Y
Winner
SYRE
+343.14%
LB
-1.69%
5Y(CAGR)
SYRE
-14.82%
LB
N/A
10Y(CAGR)
SYRE
-9.03%
LB
N/A
Max(CAGR)
SYRE
-11.13%
Winner
LB
+78.42%
SYRE vs LB - Annual Returns (2016 - 2026)
Returns include dividend reinvestment.
| Year | SYRE | LB |
|---|---|---|
| 2026 | +140.84% | +45.35% |
| 2025 | +37.36% | -23.90% |
| 2024 | +8.79% | +179.46% |
| 2023 | +104.27% | N/A |
| 2022 | -90.57% | N/A |
| 2021 | -44.51% | N/A |
| 2020 | +1.55% | N/A |
| 2019 | -4.98% | N/A |
| 2018 | +39.22% | N/A |
| 2017 | +18.38% | N/A |
| 2016 | -55.48% | N/A |
SYRE vs LB Drawdown Comparison
The maximum drawdown for SYRE was -99.11%, occurring on Jun 21, 2023. This drawdown has not yet recovered.
The maximum drawdown for LB was -48.25%, occurring on Jan 7, 2026. This drawdown has not yet recovered.
The current SYRE drawdown is -75.43%. The current LB drawdown is -17.53%.
| Rank | SYRE | LB |
|---|---|---|
| #1 | -99.11% Apr 8, 2016 - Jun 21, 2023 | -48.25% Nov 11, 2025 - Jan 7, 2026 |
| #2 | N/A | -41.99% May 16, 2025 - Nov 11, 2025 |
| #3 | N/A | -32.31% Nov 27, 2024 - Jan 21, 2025 |
| #4 | N/A | -27.77% Jan 21, 2025 - May 16, 2025 |
| #5 | N/A | -21.31% Aug 23, 2024 - Sep 24, 2024 |
| #6 | N/A | -15.76% Nov 8, 2024 - Nov 22, 2024 |
| #7 | N/A | -12.87% Jul 15, 2024 - Jul 29, 2024 |
| #8 | N/A | -8.98% Jul 31, 2024 - Aug 12, 2024 |
| #9 | N/A | -8.00% Sep 24, 2024 - Oct 1, 2024 |
| #10 | N/A | -6.07% Jul 5, 2024 - Jul 11, 2024 |
| #11 | N/A | -5.10% Nov 22, 2024 - Nov 27, 2024 |
| #12 | N/A | -4.88% Oct 18, 2024 - Oct 30, 2024 |
| #13 | N/A | -2.56% Jul 29, 2024 - Jul 31, 2024 |
| #14 | N/A | -1.68% Jul 2, 2024 - Jul 5, 2024 |
| #15 | N/A | -1.45% Aug 12, 2024 - Aug 15, 2024 |
Correlation
Correlation between SYRE and LB is 0.24 which considered as a very weak or no correlation - the stocks move independently of each other.
0.24
-101
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