STOK vs SION
Comparison between Stoke Therapeutics Inc (STOK, Company) and Sionna Therapeutics Inc (SION, Company).
Both STOK and SION are from the Healthcare sector.
STOK vs SION - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Market Cap
STOK
$1.96B
Winner
SION
$1.96B
Max Drawdown
STOK
95.17%
Winner
SION
69.36%
Sharpe Ratio
Winner
STOK
1.83
SION
1.34
5Y Beta
STOK
1.07
Winner
SION
0.95
Industry
STOK
Biotechnology
SION
Biotechnology
P/E Ratio
STOK
-10.80
Winner
SION
-22.66
Forward P/E
STOK
204.08
SION
N/A
5Y EPS CAGR
STOK
11.95%
SION
N/A
Debt to Equity
STOK
0.00%
SION
0.00%
Free Cash Flow Yield
STOK
-7.55%
Winner
SION
-3.69%
P/S Ratio
STOK
60.01
SION
N/A
P/B Ratio
Winner
STOK
4.98
SION
6.71
STOK vs SION - Historical Returns
Returns include dividend reinvestment.
1M
Winner
STOK
-8.95%
SION
-13.67%
3M
STOK
-13.39%
Winner
SION
+2.34%
6M
Winner
STOK
-2.79%
SION
-12.21%
1Y
Winner
STOK
+175.83%
SION
+120.65%
5Y(CAGR)
STOK
-4.25%
SION
N/A
Max(CAGR)
STOK
+2.33%
Winner
SION
+30.00%
STOK vs SION - Annual Returns (2019 - 2026)
Returns include dividend reinvestment.
| Year | STOK | SION |
|---|---|---|
| 2026 | -2.88% | -9.79% |
| 2025 | +181.63% | +64.56% |
| 2024 | +88.23% | N/A |
| 2023 | -42.13% | N/A |
| 2022 | -59.89% | N/A |
| 2021 | -58.69% | N/A |
| 2020 | +133.35% | N/A |
| 2019 | +10.75% | N/A |
STOK vs SION Drawdown Comparison
The maximum drawdown for STOK was -95.17%, occurring on Oct 27, 2023. This drawdown has not yet recovered.
The maximum drawdown for SION was -69.36%, occurring on Apr 10, 2025. Recovery took 137 trading sessions.
The current STOK drawdown is -57.01%. The current SION drawdown is -23.03%.
| Rank | STOK | SION |
|---|---|---|
| #1 | -95.17% Jan 19, 2021 - Oct 27, 2023 | -69.36% Feb 7, 2025 - Aug 26, 2025 |
| #2 | -55.46% Sep 3, 2019 - Oct 7, 2020 | -23.74% Feb 3, 2026 - Apr 15, 2026 |
| #3 | -21.15% Jun 28, 2019 - Aug 13, 2019 | -23.03% May 11, 2026 - Jun 5, 2026 |
| #4 | -12.41% Nov 10, 2020 - Nov 24, 2020 | -19.06% Oct 21, 2025 - Nov 21, 2025 |
| #5 | -11.65% Nov 30, 2020 - Dec 14, 2020 | -18.12% Nov 24, 2025 - Feb 3, 2026 |
| #6 | -7.73% Dec 31, 2020 - Jan 14, 2021 | -17.26% Apr 16, 2026 - May 11, 2026 |
| #7 | -7.73% Oct 27, 2020 - Nov 9, 2020 | -15.94% Aug 28, 2025 - Sep 22, 2025 |
| #8 | -6.45% Jun 21, 2019 - Jun 27, 2019 | -5.53% Oct 3, 2025 - Oct 15, 2025 |
| #9 | -5.34% Aug 26, 2019 - Aug 29, 2019 | -3.56% Sep 29, 2025 - Oct 3, 2025 |
| #10 | -4.63% Oct 16, 2020 - Oct 23, 2020 | -2.41% Oct 16, 2025 - Oct 21, 2025 |
| #11 | -4.41% Dec 21, 2020 - Dec 31, 2020 | -0.36% Aug 26, 2025 - Aug 28, 2025 |
| #12 | -2.48% Aug 20, 2019 - Aug 26, 2019 | N/A |
| #13 | -1.32% Oct 23, 2020 - Oct 27, 2020 | N/A |
| #14 | -1.18% Oct 13, 2020 - Oct 16, 2020 | N/A |
| #15 | -1.05% Dec 14, 2020 - Dec 17, 2020 | N/A |
Correlation
Correlation between STOK and SION is 0.97 which considered as a very strong positive correlation - the stocks move almost identically together.
0.97
-101
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