SION vs CMRE
Comparison between Sionna Therapeutics Inc (SION, Company) and Costamare Inc (CMRE, Company).
SION is from the Healthcare sector, while CMRE is from the Industrials sector.
SION vs CMRE - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Market Cap
Winner
SION
$1.96B
CMRE
$1.95B
Max Drawdown
Winner
SION
69.36%
CMRE
85.43%
Sharpe Ratio
SION
1.34
Winner
CMRE
2.05
5Y Beta
SION
0.95
Winner
CMRE
0.86
Industry
SION
Biotechnology
CMRE
Marine Shipping
P/E Ratio
Winner
SION
-22.66
CMRE
5.36
Forward P/E
SION
N/A
CMRE
15.06
PEG Ratio
SION
N/A
CMRE
0.40
Dividend Yield
SION
N/A
CMRE
2.95%
5Y Dividends CAGR
SION
N/A
CMRE
4.39%
5Y EPS CAGR
SION
N/A
CMRE
110.78%
Debt to Equity
Winner
SION
0.00%
CMRE
72.61%
Free Cash Flow Yield
SION
-3.69%
Winner
CMRE
27.51%
P/S Ratio
SION
N/A
CMRE
2.26
P/B Ratio
SION
6.71
Winner
CMRE
0.92
SION vs CMRE - Historical Returns
Returns include dividend reinvestment.
1M
SION
-13.67%
Winner
CMRE
-6.27%
3M
Winner
SION
+2.34%
CMRE
-4.24%
6M
SION
-12.21%
Winner
CMRE
+0.54%
1Y
Winner
SION
+120.65%
CMRE
+86.39%
5Y(CAGR)
SION
N/A
CMRE
+19.87%
10Y(CAGR)
SION
N/A
CMRE
+14.04%
Max(CAGR)
Winner
SION
+30.00%
CMRE
+10.41%
SION vs CMRE - Annual Returns (2010 - 2026)
Returns include dividend reinvestment.
| Year | SION | CMRE |
|---|---|---|
| 2026 | -9.79% | +3.43% |
| 2025 | +64.56% | +64.79% |
| 2024 | N/A | +24.89% |
| 2023 | N/A | +16.71% |
| 2022 | N/A | -23.12% |
| 2021 | N/A | +60.32% |
| 2020 | N/A | -7.96% |
| 2019 | N/A | +121.69% |
| 2018 | N/A | -22.53% |
| 2017 | N/A | +1.61% |
| 2016 | N/A | -34.75% |
| 2015 | N/A | -36.70% |
| 2014 | N/A | +4.37% |
| 2013 | N/A | +35.06% |
| 2012 | N/A | +3.26% |
| 2011 | N/A | +5.25% |
| 2010 | N/A | +22.03% |
SION vs CMRE Drawdown Comparison
The maximum drawdown for SION was -69.36%, occurring on Apr 10, 2025. Recovery took 137 trading sessions.
The maximum drawdown for CMRE was -78.28%, occurring on Mar 19, 2020. Recovery took 1791 trading sessions.
The current SION drawdown is -23.03%. The current CMRE drawdown is -10.12%.
| Rank | SION | CMRE |
|---|---|---|
| #1 | -69.36% Feb 7, 2025 - Aug 26, 2025 | -78.28% Jul 24, 2014 - Sep 2, 2021 |
| #2 | -23.74% Feb 3, 2026 - Apr 15, 2026 | -52.92% Mar 28, 2022 - May 31, 2024 |
| #3 | -23.03% May 11, 2026 - Jun 5, 2026 | -50.04% Jun 25, 2024 - Sep 8, 2025 |
| #4 | -19.06% Oct 21, 2025 - Nov 21, 2025 | -35.28% Apr 5, 2011 - Jan 31, 2013 |
| #5 | -18.12% Nov 24, 2025 - Feb 3, 2026 | -31.17% Sep 15, 2021 - Mar 17, 2022 |
| #6 | -17.26% Apr 16, 2026 - May 11, 2026 | -14.61% Sep 18, 2025 - Nov 4, 2025 |
| #7 | -15.94% Aug 28, 2025 - Sep 22, 2025 | -13.90% Nov 14, 2013 - Jan 16, 2014 |
| #8 | -5.53% Oct 3, 2025 - Oct 15, 2025 | -13.55% Mar 2, 2026 - May 29, 2026 |
| #9 | -3.56% Sep 29, 2025 - Oct 3, 2025 | -10.04% Feb 2, 2026 - Feb 26, 2026 |
| #10 | -2.41% Oct 16, 2025 - Oct 21, 2025 | -9.28% Nov 4, 2010 - Dec 2, 2010 |
| #11 | -0.36% Aug 26, 2025 - Aug 28, 2025 | -9.12% Sep 24, 2013 - Oct 24, 2013 |
| #12 | N/A | -7.99% Jul 15, 2013 - Sep 24, 2013 |
| #13 | N/A | -7.41% Jun 3, 2024 - Jun 20, 2024 |
| #14 | N/A | -7.18% Jan 31, 2013 - Mar 5, 2013 |
| #15 | N/A | -7.07% Mar 7, 2013 - Apr 26, 2013 |
Correlation
Correlation between SION and CMRE is 0.94 which considered as a very strong positive correlation - the stocks move almost identically together.
0.94
-101
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