SPPI vs LENZ

Comparison between Spectrum Pharmaceuticals Inc (SPPI, Company) and LENZ Therapeutics Inc (LENZ, Company).

5-Year PerformanceLENZ has outperformed SPPI, delivering a return of -41.0% compared to -45.3%

SPPI vs LENZ - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SPPI(COMPANY)	LENZ(COMPANY)
Market Cap	$208M	$206M
Max Drawdown	99.95%	96.98%
Sharpe Ratio	0.73	-1.47
5Y Beta	N/A	1.61
Industry	N/A	Biotechnology
P/E Ratio	-2.90	-1.84
PEG Ratio	N/A	-0.02
Debt to Equity	107.59%	0.00%
Free Cash Flow Yield	-42.54%	-42.38%
P/S Ratio	13.32	9.83
P/B Ratio	7.76	0.84

Market Cap

Winner

SPPI

$208M

LENZ

$206M

Max Drawdown

SPPI

99.95%

Winner

LENZ

96.98%

Sharpe Ratio

Winner

SPPI

0.73

LENZ

-1.47

5Y Beta

SPPI

N/A

LENZ

1.61

Industry

SPPI

N/A

LENZ

Biotechnology

P/E Ratio

Winner

SPPI

-2.90

LENZ

-1.84

PEG Ratio

SPPI

N/A

LENZ

-0.02

Debt to Equity

SPPI

107.59%

Winner

LENZ

0.00%

Free Cash Flow Yield

SPPI

-42.54%

Winner

LENZ

-42.38%

P/S Ratio

SPPI

13.32

Winner

LENZ

9.83

P/B Ratio

SPPI

7.76

Winner

LENZ

0.84

SPPI vs LENZ - Historical Returns

Returns include dividend reinvestment.

Period	SPPI	LENZ
1 month	+7.29%	-14.41%
3 months	+4.83%	-42.72%
6 months	+21.18%	-62.68%
1 year	+24.61%	-77.11%
5 years(CAGR)	-45.27%	-41.02%
10 years(CAGR)	-18.89%	N/A
Max(CAGR)	-21.10%	-41.02%

Winner

SPPI

+7.29%

LENZ

-14.41%

Winner

SPPI

+4.83%

LENZ

-42.72%

Winner

SPPI

+21.18%

LENZ

-62.68%

Winner

SPPI

+24.61%

LENZ

-77.11%

5Y(CAGR)

SPPI

-45.27%

Winner

LENZ

-41.02%

10Y(CAGR)

SPPI

-18.89%

LENZ

N/A

Max(CAGR)

Winner

SPPI

-21.10%

LENZ

-41.02%

SPPI vs LENZ - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	SPPI	LENZ
2026	N/A	-57.69%
2025	N/A	-43.44%
2024	N/A	+117.40%
2023	+169.28%	-18.38%
2022	-76.82%	-74.58%
2021	-63.29%	-32.81%
2020	-1.16%	N/A
2019	-60.56%	N/A
2018	-54.09%	N/A
2017	+324.89%	N/A
2016	-23.62%	N/A
2015	-15.66%	N/A
2014	-21.16%	N/A
2013	-24.10%	N/A
2012	-22.95%	N/A
2011	+107.81%	N/A
2010	+50.33%	N/A
2009	+196.00%	N/A
2008	-44.40%	N/A
2007	-51.08%	N/A
2006	+30.42%	N/A
2005	-34.82%	N/A
2004	-18.58%	N/A
2003	+352.43%	N/A
2002	-98.11%	N/A
2001	+8.61%	N/A
2000	-69.48%	N/A
1999	+14.03%	N/A

SPPI vs LENZ Drawdown Comparison

The maximum drawdown for SPPI was -99.95%, occurring on Dec 28, 2022. This drawdown has not yet recovered.

The maximum drawdown for LENZ was -95.80%, occurring on Jun 11, 2026. This drawdown has not yet recovered.

The current SPPI drawdown is -99.83%. The current LENZ drawdown is -95.62%.

Rank	SPPI	LENZ
#1	-99.95% Mar 7, 2000 - Dec 28, 2022	-95.80% Jun 30, 2021 - Jun 11, 2026
#2	-22.36% Nov 19, 1999 - Feb 24, 2000	N/A
#3	-6.87% Nov 5, 1999 - Nov 15, 1999	N/A
#4	-6.79% Mar 3, 2000 - Mar 7, 2000	N/A
#5	-6.19% Feb 25, 2000 - Feb 29, 2000	N/A
#6	-3.92% Nov 15, 1999 - Nov 18, 1999	N/A
#7	-3.70% Nov 1, 1999 - Nov 5, 1999	N/A