SNDX vs URGN

Comparison between Syndax Pharmaceuticals Inc (SNDX, Company) and UroGen Pharma Ltd (URGN, Company).

Both SNDX and URGN are from the Healthcare sector.

5-Year PerformanceURGN has outperformed SNDX, delivering a return of +19.8% compared to +4.4%

SNDX vs URGN - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SNDX(COMPANY)	URGN(COMPANY)
Market Cap	$1.85B	$1.85B
Max Drawdown	78.98%	93.98%
Sharpe Ratio	1.81	1.88
5Y Beta	1.04	1.19
Industry	Biotechnology	Biotechnology
P/E Ratio	-7.48	-13.44
PEG Ratio	0.00	-0.09
5Y EPS CAGR	12.13%	-11.74%
Debt to Equity	840.90%	-152.54%
Free Cash Flow Yield	-15.05%	-8.98%
P/S Ratio	8.52	13.16
P/B Ratio	44.46	19.27

Market Cap

Winner

SNDX

$1.85B

URGN

$1.85B

Max Drawdown

Winner

SNDX

78.98%

URGN

93.98%

Sharpe Ratio

SNDX

1.81

Winner

URGN

1.88

5Y Beta

Winner

SNDX

1.04

URGN

1.19

Industry

SNDX

Biotechnology

URGN

Biotechnology

P/E Ratio

SNDX

-7.48

Winner

URGN

-13.44

PEG Ratio

SNDX

0.00

Winner

URGN

-0.09

5Y EPS CAGR

Winner

SNDX

12.13%

URGN

-11.74%

Debt to Equity

SNDX

840.90%

Winner

URGN

-152.54%

Free Cash Flow Yield

SNDX

-15.05%

Winner

URGN

-8.98%

P/S Ratio

Winner

SNDX

8.52

URGN

13.16

P/B Ratio

SNDX

44.46

Winner

URGN

19.27

SNDX vs URGN - Historical Returns

Returns include dividend reinvestment.

Period	SNDX	URGN
1 month	+18.65%	+43.26%
3 months	-13.24%	+102.02%
6 months	+2.44%	+67.42%
1 year	+142.44%	+193.36%
5 years(CAGR)	+4.40%	+19.75%
10 years(CAGR)	+8.20%	+11.54%
Max(CAGR)	+5.95%	+11.54%

SNDX

+18.65%

Winner

URGN

+43.26%

SNDX

-13.24%

Winner

URGN

+102.02%

SNDX

+2.44%

Winner

URGN

+67.42%

SNDX

+142.44%

Winner

URGN

+193.36%

5Y(CAGR)

SNDX

+4.40%

Winner

URGN

+19.75%

10Y(CAGR)

SNDX

+8.20%

Winner

URGN

+11.54%

Max(CAGR)

SNDX

+5.95%

Winner

URGN

+11.54%

SNDX vs URGN - Annual Returns (2016 - 2026)

Returns include dividend reinvestment.

Year	SNDX	URGN
2026	+2.44%	+67.42%
2025	+49.22%	+118.88%
2024	-39.52%	-29.98%
2023	-15.59%	+73.61%
2022	+14.90%	-8.84%
2021	-2.01%	-47.14%
2020	+153.59%	-44.67%
2019	+97.30%	-25.03%
2018	-49.26%	+11.44%
2017	+19.67%	+166.17%
2016	-40.30%	N/A

SNDX vs URGN Drawdown Comparison

The maximum drawdown for SNDX was -78.98%, occurring on Dec 24, 2018. Recovery took 925 trading sessions.

The maximum drawdown for URGN was -93.98%, occurring on May 27, 2025. This drawdown has not yet recovered.

The current SNDX drawdown is -24.71%. The current URGN drawdown is -41.80%.

Rank	SNDX	URGN
#1	-78.98% Aug 23, 2016 - Apr 28, 2020	-93.98% May 18, 2018 - May 27, 2025
#2	-69.88% Feb 1, 2023 - Jul 7, 2025	-20.07% May 30, 2017 - Jun 26, 2017
#3	-49.24% Dec 21, 2020 - Jan 12, 2023	-18.48% Jan 25, 2018 - Mar 5, 2018
#4	-45.42% Apr 6, 2016 - Aug 23, 2016	-16.63% Sep 14, 2017 - Nov 2, 2017
#5	-36.18% May 15, 2020 - Nov 5, 2020	-15.97% Mar 14, 2018 - Apr 3, 2018
#6	-24.21% Mar 9, 2016 - Apr 5, 2016	-14.93% Nov 13, 2017 - Jan 3, 2018
#7	-12.36% Nov 5, 2020 - Nov 16, 2020	-13.38% Jun 27, 2017 - Aug 30, 2017
#8	-8.41% Mar 3, 2016 - Mar 8, 2016	-11.40% Apr 4, 2018 - May 18, 2018
#9	-7.69% Apr 28, 2020 - May 15, 2020	-5.75% Jan 16, 2018 - Jan 22, 2018
#10	-5.68% Dec 15, 2020 - Dec 21, 2020	-4.09% May 16, 2017 - May 18, 2017
#11	-5.59% Dec 9, 2020 - Dec 15, 2020	-3.88% Jan 3, 2018 - Jan 16, 2018
#12	-5.40% Dec 7, 2020 - Dec 9, 2020	-3.19% May 11, 2017 - May 15, 2017
#13	-4.38% Jan 26, 2023 - Jan 31, 2023	-2.61% Mar 9, 2018 - Mar 14, 2018
#14	-3.60% Nov 20, 2020 - Nov 25, 2020	-2.59% May 22, 2017 - May 30, 2017
#15	-3.46% Jan 12, 2023 - Jan 24, 2023	-2.21% Sep 7, 2017 - Sep 12, 2017

Correlation

Correlation between SNDX and URGN is -0.63 which considered as a moderate negative correlation - the stocks show some tendency to move in opposite directions.

-0.63

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