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SNDX vs SPY

Comparison between Syndax Pharmaceuticals Inc (SNDX, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).

5-Year PerformanceSPY has outperformed SNDX, delivering a return of +13.3% compared to +7.3%

SNDX vs SPY - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap / Net Assets
SNDX
$1.78B
Winner
SPY
$781B
Expense Ratio
SNDX
N/A
SPY
0.09%
Max Drawdown
SNDX
78.98%
Winner
SPY
56.47%
Sharpe Ratio
SNDX
1.05
Winner
SPY
1.42
5Y Beta
SNDX
1.01
Winner
SPY
1.00
Industry
SNDX
Biotechnology
SPY
N/A
P/E Ratio
Winner
SNDX
-7.93
SPY
26.48
Forward P/E
SNDX
N/A
SPY
20.90
PEG Ratio
Winner
SNDX
0.00
SPY
0.30
5Y Dividends CAGR
SNDX
N/A
SPY
6.00%
5Y EPS CAGR
SNDX
9.46%
Winner
SPY
26.40%
Debt to Equity
SNDX
2318.03%
Winner
SPY
48.17%
Free Cash Flow Yield
SNDX
-12.43%
SPY
N/A
P/S Ratio
SNDX
8.19
Winner
SPY
3.72
P/B Ratio
SNDX
40.56
Winner
SPY
5.55

SNDX vs SPY - Historical Returns

Returns include dividend reinvestment.

1M
SNDX
-12.22%
Winner
SPY
+3.42%
3M
SNDX
-0.68%
Winner
SPY
+5.97%
6M
SNDX
-2.90%
Winner
SPY
+12.56%
1Y
Winner
SNDX
+60.38%
SPY
+23.65%
5Y(CAGR)
SNDX
+7.35%
Winner
SPY
+13.33%
10Y(CAGR)
SNDX
+4.39%
Winner
SPY
+15.34%
Max(CAGR)
SNDX
+5.21%
Winner
SPY
+8.61%

SNDX vs SPY - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

YearSNDXSPY
2026-4.23%+13.79%
2025+49.22%+18.00%
2024-39.52%+25.59%
2023-15.59%+26.72%
2022+14.90%-18.64%
2021-2.01%+30.52%
2020+153.59%+17.28%
2019+97.30%+31.09%
2018-49.26%-5.24%
2017+19.67%+20.78%
2016-40.30%+13.59%
2015N/A+1.31%
2014N/A+14.56%
2013N/A+29.00%
2012N/A+14.17%
2011N/A+0.85%
2010N/A+13.14%
2009N/A+22.67%
2008N/A-36.25%
2007N/A+5.32%
2006N/A+13.85%
2005N/A+5.32%
2004N/A+10.75%
2003N/A+24.18%
2002N/A-22.42%
2001N/A-10.13%
2000N/A-8.84%
1999N/A+8.61%

SNDX vs SPY Drawdown Comparison

The maximum drawdown for SNDX was -78.98%, occurring on Dec 24, 2018. Recovery took 925 trading sessions.

The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.

The current SNDX drawdown is -29.61%.

RankSNDXSPY
#1-78.98%
Aug 23, 2016 - Apr 28, 2020		-55.20%
Oct 9, 2007 - Aug 16, 2012
#2-69.88%
Feb 1, 2023 - Jul 7, 2025		-47.50%
Mar 24, 2000 - Oct 26, 2006
#3-49.24%
Dec 21, 2020 - Jan 12, 2023		-33.70%
Feb 19, 2020 - Aug 10, 2020
#4-45.42%
Apr 6, 2016 - Aug 23, 2016		-24.50%
Jan 3, 2022 - Dec 13, 2023
#5-36.18%
May 15, 2020 - Nov 5, 2020		-19.34%
Sep 20, 2018 - Apr 12, 2019
#6-24.21%
Mar 9, 2016 - Apr 5, 2016		-18.76%
Feb 19, 2025 - Jun 26, 2025
#7-12.36%
Nov 5, 2020 - Nov 16, 2020		-13.02%
Jul 20, 2015 - Apr 18, 2016
#8-8.41%
Mar 3, 2016 - Mar 8, 2016		-10.10%
Jan 26, 2018 - Aug 6, 2018
#9-7.69%
Apr 28, 2020 - May 15, 2020		-9.44%
Sep 2, 2020 - Nov 11, 2020
#10-5.68%
Dec 15, 2020 - Dec 21, 2020		-9.30%
Jan 19, 2000 - Mar 17, 2000
#11-5.59%
Dec 9, 2020 - Dec 15, 2020		-9.05%
Jul 19, 2007 - Oct 5, 2007
#12-5.40%
Dec 7, 2020 - Dec 9, 2020		-8.88%
Jan 27, 2026 - Apr 14, 2026
#13-4.38%
Jan 26, 2023 - Jan 31, 2023		-8.41%
Jul 16, 2024 - Sep 19, 2024
#14-3.60%
Nov 20, 2020 - Nov 25, 2020		-7.35%
Sep 14, 2012 - Jan 2, 2013
#15-3.46%
Jan 12, 2023 - Jan 24, 2023		-7.27%
Sep 18, 2014 - Oct 31, 2014

Correlation

Correlation between SNDX and SPY is 0.54 which considered as a moderate positive correlation - the stocks show some tendency to move together.

0.54
-101

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