SNDX vs TSHA

Comparison between Syndax Pharmaceuticals Inc (SNDX, Company) and Taysha Gene Therapies Inc (TSHA, Company).

Both SNDX and TSHA are from the Healthcare sector.

5-Year PerformanceSNDX has outperformed TSHA, delivering a return of -0.5% compared to -25.3%

SNDX vs TSHA - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SNDX(COMPANY)	TSHA(COMPANY)
Market Cap	$1.56B	$1.55B
Max Drawdown	78.98%	98.14%
Sharpe Ratio	1.03	1.22
5Y Beta	1.06	1.40
Industry	Biotechnology	Biotechnology
P/E Ratio	-6.29	-11.65
PEG Ratio	0.00	-1.29
5Y EPS CAGR	12.13%	N/A
Debt to Equity	840.90%	23.10%
Free Cash Flow Yield	-17.88%	-7.27%
P/S Ratio	7.21	207.70
P/B Ratio	37.64	7.32

Market Cap

Winner

SNDX

$1.56B

TSHA

$1.55B

Max Drawdown

Winner

SNDX

78.98%

TSHA

98.14%

Sharpe Ratio

SNDX

1.03

Winner

TSHA

1.22

5Y Beta

Winner

SNDX

1.06

TSHA

1.40

Industry

SNDX

Biotechnology

TSHA

Biotechnology

P/E Ratio

SNDX

-6.29

Winner

TSHA

-11.65

PEG Ratio

SNDX

0.00

Winner

TSHA

-1.29

5Y EPS CAGR

SNDX

12.13%

TSHA

N/A

Debt to Equity

SNDX

840.90%

Winner

TSHA

23.10%

Free Cash Flow Yield

SNDX

-17.88%

Winner

TSHA

-7.27%

P/S Ratio

Winner

SNDX

7.21

TSHA

207.70

P/B Ratio

SNDX

37.64

Winner

TSHA

7.32

SNDX vs TSHA - Historical Returns

Returns include dividend reinvestment.

Period	SNDX	TSHA
1 month	-10.58%	-16.64%
3 months	-23.93%	+23.86%
6 months	-10.41%	-1.38%
1 year	+71.04%	+115.47%
5 years(CAGR)	-0.55%	-25.27%
10 years(CAGR)	+3.47%	N/A
Max(CAGR)	+4.16%	-22.25%

Winner

SNDX

-10.58%

TSHA

-16.64%

SNDX

-23.93%

Winner

TSHA

+23.86%

SNDX

-10.41%

Winner

TSHA

-1.38%

SNDX

+71.04%

Winner

TSHA

+115.47%

5Y(CAGR)

Winner

SNDX

-0.55%

TSHA

-25.27%

10Y(CAGR)

SNDX

+3.47%

TSHA

N/A

Max(CAGR)

Winner

SNDX

+4.16%

TSHA

-22.25%

SNDX vs TSHA - Annual Returns (2016 - 2026)

Returns include dividend reinvestment.

Year	SNDX	TSHA
2026	-14.32%	+8.76%
2025	+49.22%	+197.30%
2024	-39.52%	+1.17%
2023	-15.59%	-19.55%
2022	+14.90%	-80.94%
2021	-2.01%	-55.48%
2020	+153.59%	+10.31%
2019	+97.30%	N/A
2018	-49.26%	N/A
2017	+19.67%	N/A
2016	-40.30%	N/A

SNDX vs TSHA Drawdown Comparison

The maximum drawdown for SNDX was -78.98%, occurring on Dec 24, 2018. Recovery took 925 trading sessions.

The maximum drawdown for TSHA was -98.14%, occurring on Jun 28, 2023. This drawdown has not yet recovered.

The current SNDX drawdown is -37.03%. The current TSHA drawdown is -82.02%.

Rank	SNDX	TSHA
#1	-78.98% Aug 23, 2016 - Apr 28, 2020	-98.14% Jan 20, 2021 - Jun 28, 2023
#2	-69.88% Feb 1, 2023 - Jul 7, 2025	-21.78% Sep 25, 2020 - Dec 23, 2020
#3	-49.24% Dec 21, 2020 - Jan 12, 2023	-10.74% Dec 23, 2020 - Jan 14, 2021
#4	-45.42% Apr 6, 2016 - Aug 23, 2016	N/A
#5	-36.18% May 15, 2020 - Nov 5, 2020	N/A
#6	-24.21% Mar 9, 2016 - Apr 5, 2016	N/A
#7	-12.36% Nov 5, 2020 - Nov 16, 2020	N/A
#8	-8.41% Mar 3, 2016 - Mar 8, 2016	N/A
#9	-7.69% Apr 28, 2020 - May 15, 2020	N/A
#10	-5.68% Dec 15, 2020 - Dec 21, 2020	N/A
#11	-5.59% Dec 9, 2020 - Dec 15, 2020	N/A
#12	-5.40% Dec 7, 2020 - Dec 9, 2020	N/A
#13	-4.38% Jan 26, 2023 - Jan 31, 2023	N/A
#14	-3.60% Nov 20, 2020 - Nov 25, 2020	N/A
#15	-3.46% Jan 12, 2023 - Jan 24, 2023	N/A