SLN vs CIO

Comparison between Silence Therapeutics Plc (SLN, Company) and CITY OFFICE REIT, INC. (CIO, Company).

SLN is from the Healthcare sector, while CIO is from the Real Estate sector.

5-Year PerformanceCIO has outperformed SLN, delivering a return of +0.4% compared to -25.1%

SLN vs CIO - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SLN(COMPANY)	CIO(COMPANY)
Market Cap	$283M	$282M
Max Drawdown	92.31%	83.69%
Sharpe Ratio	0.65	0.95
5Y Beta	0.87	N/A
Industry	Biotechnology	Reit - Office
P/E Ratio	-3.78	-2.32
Forward P/E	N/A	384.62
PEG Ratio	-0.85	-0.00
Dividend Yield	N/A	4.29%
5Y Dividends CAGR	N/A	-13.03%
Debt to Equity	0.00%	65.30%
Free Cash Flow Yield	-23.15%	16.87%
P/S Ratio	337.79	N/A
P/B Ratio	5.75	N/A

Market Cap

Winner

SLN

$283M

CIO

$282M

Max Drawdown

SLN

92.31%

Winner

CIO

83.69%

Sharpe Ratio

SLN

0.65

Winner

CIO

0.95

5Y Beta

SLN

0.87

CIO

N/A

Industry

SLN

Biotechnology

CIO

Reit - Office

P/E Ratio

Winner

SLN

-3.78

CIO

-2.32

Forward P/E

SLN

N/A

CIO

384.62

PEG Ratio

Winner

SLN

-0.85

CIO

-0.00

Dividend Yield

SLN

N/A

CIO

4.29%

5Y Dividends CAGR

SLN

N/A

CIO

-13.03%

Debt to Equity

Winner

SLN

0.00%

CIO

65.30%

Free Cash Flow Yield

SLN

-23.15%

Winner

CIO

16.87%

P/S Ratio

SLN

337.79

CIO

N/A

P/B Ratio

SLN

5.75

CIO

N/A

SLN vs CIO - Historical Returns

Returns include dividend reinvestment.

Period	SLN	CIO
1 month	-1.47%	+0.58%
3 months	-4.02%	+0.43%
6 months	+5.85%	+27.71%
1 year	+19.79%	+37.94%
5 years(CAGR)	-25.06%	+0.37%
10 years(CAGR)	N/A	+1.63%
Max(CAGR)	-16.96%	+2.20%

SLN

-1.47%

Winner

CIO

+0.58%

SLN

-4.02%

Winner

CIO

+0.43%

SLN

+5.85%

Winner

CIO

+27.71%

SLN

+19.79%

Winner

CIO

+37.94%

5Y(CAGR)

SLN

-25.06%

Winner

CIO

+0.37%

10Y(CAGR)

SLN

N/A

CIO

+1.63%

Max(CAGR)

SLN

-16.96%

Winner

CIO

+2.20%

SLN vs CIO - Annual Returns (2014 - 2026)

Returns include dividend reinvestment.

Year	SLN	CIO
2026	+8.78%	+0.14%
2025	-15.44%	+36.42%
2024	-62.91%	-5.33%
2023	+18.24%	-20.35%
2022	-36.17%	-55.54%
2021	-0.46%	+117.79%
2020	+12.82%	-20.68%
2019	N/A	+41.86%
2018	N/A	-14.64%
2017	N/A	+4.93%
2016	N/A	+15.61%
2015	N/A	-0.04%
2014	N/A	+8.52%

SLN vs CIO Drawdown Comparison

The maximum drawdown for SLN was -92.31%, occurring on Apr 9, 2025. This drawdown has not yet recovered.

The maximum drawdown for CIO was -80.90%, occurring on Oct 27, 2023. This drawdown has not yet recovered.

The current SLN drawdown is -76.40%. The current CIO drawdown is -56.00%.

Rank	SLN	CIO
#1	-92.31% Jun 28, 2021 - Apr 9, 2025	-80.90% Jan 6, 2022 - Oct 27, 2023
#2	-23.08% Sep 8, 2020 - Nov 9, 2020	-52.69% Feb 18, 2020 - Jul 26, 2021
#3	-20.24% Feb 22, 2021 - Jun 11, 2021	-24.56% Oct 5, 2017 - Jul 5, 2018
#4	-16.46% Nov 9, 2020 - Dec 23, 2020	-21.53% Apr 7, 2015 - Mar 18, 2016
#5	-9.17% Jan 4, 2021 - Jan 22, 2021	-21.53% Aug 28, 2018 - Jun 13, 2019
#6	-8.45% Jun 11, 2021 - Jun 28, 2021	-15.24% Oct 26, 2021 - Dec 22, 2021
#7	-4.59% Jan 27, 2021 - Feb 17, 2021	-13.83% Mar 18, 2016 - Jun 30, 2016
#8	-2.85% Jan 22, 2021 - Jan 26, 2021	-13.15% Aug 1, 2016 - Aug 31, 2017
#9	-2.61% Feb 18, 2021 - Feb 22, 2021	-11.77% Sep 26, 2019 - Jan 21, 2020
#10	N/A	-8.03% Jun 16, 2014 - Jul 10, 2014
#11	N/A	-7.34% Oct 14, 2014 - Apr 2, 2015
#12	N/A	-6.37% Jun 20, 2019 - Jul 30, 2019
#13	N/A	-5.00% Sep 7, 2021 - Sep 22, 2021
#14	N/A	-4.86% Jul 11, 2014 - Aug 27, 2014
#15	N/A	-4.43% Aug 27, 2014 - Sep 19, 2014