StockComparison Logo
vs

SGMO vs SPY

Comparison between Sangamo Therapeutics Inc (SGMO, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).

5-Year PerformanceSPY has outperformed SGMO, delivering a return of +12.6% compared to -62.2%

SGMO vs SPY - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap / Net Assets
SGMO
$29M
Winner
SPY
$781B
Expense Ratio
SGMO
N/A
SPY
0.09%
Max Drawdown
SGMO
99.85%
Winner
SPY
56.47%
Sharpe Ratio
SGMO
-0.77
Winner
SPY
0.91
5Y Beta
SGMO
N/A
SPY
1.00
Industry
SGMO
Biotechnology
SPY
N/A
P/E Ratio
Winner
SGMO
-0.23
SPY
28.44
Forward P/E
Winner
SGMO
0.40
SPY
21.15
5Y Dividends CAGR
SGMO
N/A
SPY
6.00%
5Y EPS CAGR
SGMO
-3.12%
Winner
SPY
25.40%
Debt to Equity
Winner
SGMO
0.00%
SPY
31.56%
P/S Ratio
SGMO
N/A
SPY
3.70
P/B Ratio
SGMO
N/A
SPY
5.59

SGMO vs SPY - Historical Returns

Returns include dividend reinvestment.

1M
Winner
SGMO
+0.00%
SPY
-0.68%
3M
SGMO
-37.92%
Winner
SPY
+3.47%
6M
SGMO
-86.18%
Winner
SPY
+7.76%
1Y
SGMO
-86.42%
Winner
SPY
+18.19%
5Y(CAGR)
SGMO
-62.20%
Winner
SPY
+12.60%
10Y(CAGR)
SGMO
-35.91%
Winner
SPY
+14.91%
Max(CAGR)
SGMO
-18.29%
Winner
SPY
+8.45%

SGMO vs SPY - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

YearSGMOSPY
2026-83.13%+9.14%
2025-62.83%+18.00%
2024+83.35%+25.59%
2023-82.70%+26.72%
2022-59.85%-18.64%
2021-52.89%+30.52%
2020+90.07%+17.28%
2019-28.95%+31.09%
2018-34.59%-5.24%
2017+429.03%+20.78%
2016-65.92%+13.59%
2015-40.21%+1.31%
2014+10.30%+14.56%
2013+125.85%+29.00%
2012+103.04%+14.17%
2011-59.72%+0.85%
2010+8.14%+13.14%
2009+61.31%+22.67%
2008-72.25%-36.25%
2007+97.29%+5.32%
2006+60.98%+13.85%
2005-30.52%+5.32%
2004+9.29%+10.75%
2003+59.48%+24.18%
2002-66.14%-22.42%
2001-45.86%-10.13%
2000+29.48%-8.84%
1999N/A+8.61%

SGMO vs SPY Drawdown Comparison

The maximum drawdown for SGMO was -99.85%, occurring on Jun 23, 2026. This drawdown has not yet recovered.

The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.

The current SGMO drawdown is -99.85%. The current SPY drawdown is -2.11%.

RankSGMOSPY
#1-99.85%
Sep 1, 2000 - Jun 23, 2026
-55.20%
Oct 9, 2007 - Aug 16, 2012
#2-56.01%
Apr 6, 2000 - Jun 12, 2000
-47.50%
Mar 24, 2000 - Oct 26, 2006
#3-41.46%
Jul 24, 2000 - Aug 29, 2000
-33.70%
Feb 19, 2020 - Aug 10, 2020
#4-20.03%
Jun 12, 2000 - Jun 20, 2000
-24.50%
Jan 3, 2022 - Dec 13, 2023
#5-15.18%
Jul 11, 2000 - Jul 18, 2000
-19.34%
Sep 20, 2018 - Apr 12, 2019
#6-6.25%
Jun 23, 2000 - Jun 27, 2000
-18.76%
Feb 19, 2025 - Jun 26, 2025
#7-5.08%
Jul 5, 2000 - Jul 7, 2000
-13.02%
Jul 20, 2015 - Apr 18, 2016
#8-2.71%
Jun 30, 2000 - Jul 5, 2000
-10.10%
Jan 26, 2018 - Aug 6, 2018
#9-0.54%
Jun 28, 2000 - Jun 30, 2000
-9.44%
Sep 2, 2020 - Nov 11, 2020
#10N/A-9.30%
Jan 19, 2000 - Mar 17, 2000
#11N/A-9.05%
Jul 19, 2007 - Oct 5, 2007
#12N/A-8.88%
Jan 27, 2026 - Apr 14, 2026
#13N/A-8.41%
Jul 16, 2024 - Sep 19, 2024
#14N/A-7.35%
Sep 14, 2012 - Jan 2, 2013
#15N/A-7.27%
Sep 18, 2014 - Oct 31, 2014

Correlation

Correlation between SGMO and SPY is -0.30 which considered as a weak negative correlation - the stocks show a slight tendency to move in opposite directions.

-0.30
-101

Select Stocks to Compare

Popular: SGMO vs SPY

More Comparisons

Compare with similar stocks