SEPN vs NVAX
Comparison between Septerna Inc (SEPN, Company) and Novavax Inc (NVAX, Company).
Both SEPN and NVAX are from the Healthcare sector.
SEPN vs NVAX - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Market Cap
SEPN
$1.55B
Winner
NVAX
$1.56B
Max Drawdown
Winner
SEPN
81.47%
NVAX
98.82%
Sharpe Ratio
Winner
SEPN
1.94
NVAX
0.75
5Y Beta
Winner
SEPN
1.25
NVAX
1.47
Industry
SEPN
Biotechnology
NVAX
Biotechnology
P/E Ratio
Winner
SEPN
-42.93
NVAX
-17.56
Forward P/E
SEPN
107.53
Winner
NVAX
2.58
PEG Ratio
SEPN
N/A
NVAX
1.32
5Y EPS CAGR
SEPN
N/A
NVAX
-42.97%
Debt to Equity
SEPN
0.00%
Winner
NVAX
-201.05%
Free Cash Flow Yield
Winner
SEPN
6.88%
NVAX
-5.89%
P/S Ratio
SEPN
21.59
Winner
NVAX
2.61
P/B Ratio
Winner
SEPN
4.13
NVAX
41.23
SEPN vs NVAX - Historical Returns
Returns include dividend reinvestment.
1M
Winner
SEPN
+17.82%
NVAX
+9.74%
3M
Winner
SEPN
+44.24%
NVAX
+18.55%
6M
Winner
SEPN
+35.67%
NVAX
+24.15%
1Y
Winner
SEPN
+230.23%
NVAX
+43.12%
5Y(CAGR)
SEPN
N/A
NVAX
-44.88%
10Y(CAGR)
SEPN
N/A
NVAX
-24.11%
Max(CAGR)
Winner
SEPN
+35.48%
NVAX
-8.46%
SEPN vs NVAX - Annual Returns (1999 - 2026)
Returns include dividend reinvestment.
| Year | SEPN | NVAX |
|---|---|---|
| 2026 | +28.06% | +32.68% |
| 2025 | +30.59% | -21.59% |
| 2024 | +7.01% | +59.84% |
| 2023 | N/A | -50.97% |
| 2022 | N/A | -92.81% |
| 2021 | N/A | +26.63% |
| 2020 | N/A | +2383.52% |
| 2019 | N/A | -89.90% |
| 2018 | N/A | +41.54% |
| 2017 | N/A | -2.36% |
| 2016 | N/A | -84.01% |
| 2015 | N/A | +45.66% |
| 2014 | N/A | +13.82% |
| 2013 | N/A | +159.90% |
| 2012 | N/A | +36.96% |
| 2011 | N/A | -50.97% |
| 2010 | N/A | -13.52% |
| 2009 | N/A | +31.68% |
| 2008 | N/A | -42.02% |
| 2007 | N/A | -13.95% |
| 2006 | N/A | +5.67% |
| 2005 | N/A | +18.83% |
| 2004 | N/A | -45.76% |
| 2003 | N/A | +114.29% |
| 2002 | N/A | -80.91% |
| 2001 | N/A | +67.66% |
| 2000 | N/A | +47.83% |
| 1999 | N/A | +12.40% |
SEPN vs NVAX Drawdown Comparison
The maximum drawdown for SEPN was -81.47%, occurring on Apr 1, 2025. Recovery took 230 trading sessions.
The maximum drawdown for NVAX was -98.82%, occurring on Feb 5, 2024. This drawdown has not yet recovered.
The current SEPN drawdown is -4.04%. The current NVAX drawdown is -97.04%.
| Rank | SEPN | NVAX |
|---|---|---|
| #1 | -81.47% Dec 23, 2024 - Nov 24, 2025 | -98.82% Feb 8, 2021 - Feb 5, 2024 |
| #2 | -25.18% Feb 24, 2026 - May 28, 2026 | -98.77% Oct 9, 2001 - Feb 8, 2021 |
| #3 | -21.10% Dec 19, 2025 - Feb 17, 2026 | -58.91% Mar 8, 2000 - Aug 3, 2001 |
| #4 | -16.77% Dec 4, 2024 - Dec 23, 2024 | -28.27% Sep 10, 2001 - Oct 3, 2001 |
| #5 | -16.19% Nov 7, 2024 - Dec 4, 2024 | -18.43% Nov 5, 1999 - Dec 16, 1999 |
| #6 | -13.97% Nov 26, 2025 - Dec 19, 2025 | -12.63% Dec 17, 1999 - Jan 20, 2000 |
| #7 | -10.63% Feb 17, 2026 - Feb 24, 2026 | -10.34% Jan 21, 2000 - Feb 8, 2000 |
| #8 | -10.36% Jun 26, 2026 - Jul 6, 2026 | -8.57% Aug 22, 2001 - Sep 10, 2001 |
| #9 | -6.45% Oct 25, 2024 - Oct 31, 2024 | -8.06% Feb 11, 2000 - Mar 1, 2000 |
| #10 | -5.55% Jun 23, 2026 - Jun 26, 2026 | -6.68% Mar 6, 2000 - Mar 8, 2000 |
| #11 | -4.76% Oct 31, 2024 - Nov 4, 2024 | -5.02% Oct 3, 2001 - Oct 9, 2001 |
| #12 | -3.65% Jun 18, 2026 - Jun 23, 2026 | -3.72% Aug 6, 2001 - Aug 9, 2001 |
| #13 | -3.57% May 28, 2026 - Jun 4, 2026 | -2.91% Aug 13, 2001 - Aug 22, 2001 |
| #14 | -3.45% Nov 4, 2024 - Nov 6, 2024 | -1.86% Mar 2, 2000 - Mar 6, 2000 |
| #15 | -3.06% Jun 4, 2026 - Jun 11, 2026 | N/A |
Correlation
Correlation between SEPN and NVAX is 0.63 which considered as a moderate positive correlation - the stocks show some tendency to move together.
0.63
-101
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