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SEPN vs ASGN

Comparison between Septerna Inc (SEPN, Company) and ASGN Inc (ASGN, Company).

SEPN is from the Healthcare sector, while ASGN is from the Technology sector.

SEPN vs ASGN - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap
Winner
SEPN
$1.62B
ASGN
$1.61B
Max Drawdown
Winner
SEPN
81.47%
ASGN
95.98%
Sharpe Ratio
Winner
SEPN
2.26
ASGN
-1.19
5Y Beta
SEPN
1.32
Winner
ASGN
0.90
Industry
SEPN
Biotechnology
ASGN
Information Technology Services
P/E Ratio
Winner
SEPN
-44.87
ASGN
17.01
Forward P/E
SEPN
107.53
Winner
ASGN
7.49
5Y EPS CAGR
SEPN
N/A
ASGN
-9.97%
Debt to Equity
Winner
SEPN
0.00%
ASGN
81.72%
Free Cash Flow Yield
SEPN
6.58%
Winner
ASGN
18.01%

SEPN vs ASGN - Historical Returns

Returns include dividend reinvestment.

1M
Winner
SEPN
+37.53%
ASGN
-48.73%
3M
Winner
SEPN
+50.02%
ASGN
-61.74%
6M
Winner
SEPN
+31.34%
ASGN
-56.11%
1Y
Winner
SEPN
+244.80%
ASGN
-66.64%
5Y(CAGR)
SEPN
N/A
ASGN
-28.77%
10Y(CAGR)
SEPN
N/A
ASGN
-6.10%
Max(CAGR)
Winner
SEPN
+37.57%
ASGN
+1.13%

SEPN vs ASGN - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

YearSEPNASGN
2026+29.27%-58.14%
2025+30.59%-41.87%
2024+7.01%-12.89%
2023N/A+16.63%
2022N/A-34.32%
2021N/A+53.18%
2020N/A+17.33%
2019N/A+30.68%
2018N/A-13.98%
2017N/A+44.04%
2016N/A+3.23%
2015N/A+38.27%
2014N/A-3.52%
2013N/A+58.73%
2012N/A+84.03%
2011N/A+31.37%
2010N/A+10.14%
2009N/A+29.06%
2008N/A-11.13%
2007N/A-40.34%
2006N/A+13.53%
2005N/A+111.84%
2004N/A-2.81%
2003N/A-41.00%
2002N/A-63.53%
2001N/A-20.46%
2000N/A+90.76%
1999N/A+3.03%

SEPN vs ASGN Drawdown Comparison

The maximum drawdown for SEPN was -81.47%, occurring on Apr 1, 2025. Recovery took 230 trading sessions.

The maximum drawdown for ASGN was -95.98%, occurring on Mar 5, 2009. Recovery took 3347 trading sessions.

The current ASGN drawdown is -85.12%.

RankSEPNASGN
#1-81.47%
Dec 23, 2024 - Nov 24, 2025
-95.98%
Jun 28, 2000 - Oct 18, 2013
#2-25.18%
Feb 24, 2026 - May 28, 2026
-85.12%
Jan 4, 2022 - Apr 23, 2026
#3-21.10%
Dec 19, 2025 - Feb 17, 2026
-66.63%
Aug 2, 2018 - Feb 10, 2021
#4-16.77%
Dec 4, 2024 - Dec 23, 2024
-37.70%
Dec 1, 2015 - Feb 16, 2017
#5-16.19%
Nov 7, 2024 - Dec 4, 2024
-32.19%
Apr 1, 2014 - Feb 20, 2015
#6-13.97%
Nov 26, 2025 - Dec 19, 2025
-27.64%
Apr 27, 2000 - Jun 28, 2000
#7-10.63%
Feb 17, 2026 - Feb 24, 2026
-17.73%
Apr 14, 2015 - Jun 18, 2015
#8-6.45%
Oct 25, 2024 - Oct 31, 2024
-17.66%
Jul 13, 2017 - Oct 3, 2017
#9-4.76%
Oct 31, 2024 - Nov 4, 2024
-17.01%
Dec 26, 2013 - Mar 6, 2014
#10-3.57%
May 28, 2026 - Jun 4, 2026
-16.00%
Jul 16, 2015 - Oct 28, 2015
#11-3.45%
Nov 4, 2024 - Nov 6, 2024
-14.83%
Apr 16, 2021 - Aug 25, 2021
#12-3.06%
Jun 4, 2026 - Jun 11, 2026
-12.57%
Feb 4, 2000 - Feb 9, 2000
#13-2.39%
Jun 15, 2026 - Jun 18, 2026
-11.15%
Nov 23, 2021 - Jan 4, 2022
#14-1.89%
Nov 24, 2025 - Nov 26, 2025
-11.00%
Apr 4, 2000 - Apr 20, 2000
#15N/A-10.31%
Mar 21, 2018 - Jul 25, 2018

Correlation

Correlation between SEPN and ASGN is -0.08 which considered as a very weak or no correlation - the stocks move independently of each other.

-0.08
-101

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