SCLX vs MCRB

Comparison between Scilex Holding Company (SCLX, Company) and Seres Therapeutics Inc (MCRB, Company).

Both SCLX and MCRB are from the Healthcare sector.

5-Year PerformanceSCLX has outperformed MCRB, delivering a return of -49.0% compared to -56.8%

SCLX vs MCRB - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SCLX(COMPANY)	MCRB(COMPANY)
Market Cap	$63M	$63M
Max Drawdown	99.23%	99.45%
Sharpe Ratio	1.33	0.40
5Y Beta	0.98	0.96
Industry	Drug Manufacturers - General	Biotechnology
P/E Ratio	-0.17	-1.32
Forward P/E	2.66	10.26
PEG Ratio	-0.00	N/A
5Y EPS CAGR	N/A	-26.82%
Debt to Equity	-32.41%	0.00%
Free Cash Flow Yield	-5.41%	-66.83%

Market Cap

Winner

SCLX

$63M

MCRB

$63M

Max Drawdown

Winner

SCLX

99.23%

MCRB

99.45%

Sharpe Ratio

Winner

SCLX

1.33

MCRB

0.40

5Y Beta

SCLX

0.98

Winner

MCRB

0.96

Industry

SCLX

Drug Manufacturers - General

MCRB

Biotechnology

P/E Ratio

SCLX

-0.17

Winner

MCRB

-1.32

Forward P/E

Winner

SCLX

2.66

MCRB

10.26

PEG Ratio

SCLX

-0.00

MCRB

N/A

5Y EPS CAGR

SCLX

N/A

MCRB

-26.82%

Debt to Equity

Winner

SCLX

-32.41%

MCRB

0.00%

Free Cash Flow Yield

Winner

SCLX

-5.41%

MCRB

-66.83%

SCLX vs MCRB - Historical Returns

Returns include dividend reinvestment.

Period	SCLX	MCRB
1 month	+100.62%	-12.91%
3 months	+55.40%	-26.80%
6 months	-17.89%	-56.74%
1 year	+150.45%	-14.49%
5 years(CAGR)	-48.99%	-56.75%
10 years(CAGR)	N/A	-36.16%
Max(CAGR)	-47.02%	-36.85%

Winner

SCLX

+100.62%

MCRB

-12.91%

Winner

SCLX

+55.40%

MCRB

-26.80%

Winner

SCLX

-17.89%

MCRB

-56.74%

Winner

SCLX

+150.45%

MCRB

-14.49%

5Y(CAGR)

Winner

SCLX

-48.99%

MCRB

-56.75%

10Y(CAGR)

SCLX

N/A

MCRB

-36.16%

Max(CAGR)

SCLX

-47.02%

Winner

MCRB

-36.85%

SCLX vs MCRB - Annual Returns (2015 - 2026)

Returns include dividend reinvestment.

Year	SCLX	MCRB
2026	-8.35%	-56.37%
2025	-20.13%	-11.78%
2024	-79.10%	-40.64%
2023	-61.61%	-74.07%
2022	-60.30%	-36.65%
2021	+1.93%	-66.76%
2020	N/A	+631.34%
2019	N/A	-28.57%
2018	N/A	-57.16%
2017	N/A	+1.30%
2016	N/A	-70.97%
2015	N/A	-31.73%

SCLX vs MCRB Drawdown Comparison

The maximum drawdown for SCLX was -99.23%, occurring on Apr 22, 2025. This drawdown has not yet recovered.

The maximum drawdown for MCRB was -99.45%, occurring on Jun 15, 2026. This drawdown has not yet recovered.

The current SCLX drawdown is -97.68%. The current MCRB drawdown is -99.36%.

Rank	SCLX	MCRB
#1	-99.23% Apr 12, 2023 - Apr 22, 2025	-99.45% Jun 26, 2015 - Jun 15, 2026
#2	-72.67% Nov 8, 2022 - Jan 19, 2023	N/A
#3	-42.23% Jan 20, 2023 - Apr 5, 2023	N/A
#4	-16.08% Oct 26, 2022 - Nov 8, 2022	N/A
#5	-8.13% Apr 10, 2023 - Apr 12, 2023	N/A
#6	-1.26% Jun 27, 2022 - Oct 13, 2022	N/A
#7	-1.21% Mar 11, 2021 - Apr 19, 2021	N/A
#8	-0.80% Apr 19, 2021 - Aug 30, 2021	N/A
#9	-0.59% Nov 2, 2021 - Jan 24, 2022	N/A
#10	-0.50% Oct 18, 2021 - Nov 2, 2021	N/A
#11	-0.40% Jan 24, 2022 - Feb 2, 2022	N/A
#12	-0.39% Mar 17, 2022 - May 4, 2022	N/A
#13	-0.29% May 5, 2022 - May 25, 2022	N/A
#14	-0.29% May 27, 2022 - Jun 21, 2022	N/A
#15	-0.28% Sep 14, 2021 - Oct 14, 2021	N/A