SAIA vs IONS

Comparison between Saia Inc (SAIA, Company) and Ionis Pharmaceuticals Inc (IONS, Company).

SAIA is from the Industrials sector, while IONS is from the Healthcare sector.

5-Year PerformanceIONS has outperformed SAIA, delivering a return of +16.5% compared to +15.6%

SAIA vs IONS - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	SAIA(COMPANY)	IONS(COMPANY)
Market Cap	$12B	$12B
Max Drawdown	80.35%	91.72%
Sharpe Ratio	1.27	1.91
5Y Beta	1.43	0.75
Industry	Trucking	Biotechnology
P/E Ratio	48.73	-71.23
Forward P/E	40.82	90.91
PEG Ratio	2.44	-1.50
5Y EPS CAGR	11.22%	-21.44%
Debt to Equity	4.26%	88.01%
Free Cash Flow Yield	1.56%	-7.80%
P/S Ratio	3.81	11.70
P/B Ratio	4.54	25.24

Market Cap

SAIA

$12B

Winner

IONS

$12B

Max Drawdown

Winner

SAIA

80.35%

IONS

91.72%

Sharpe Ratio

SAIA

1.27

Winner

IONS

1.91

5Y Beta

SAIA

1.43

Winner

IONS

0.75

Industry

SAIA

Trucking

IONS

Biotechnology

P/E Ratio

SAIA

48.73

Winner

IONS

-71.23

Forward P/E

Winner

SAIA

40.82

IONS

90.91

PEG Ratio

SAIA

2.44

Winner

IONS

-1.50

5Y EPS CAGR

Winner

SAIA

11.22%

IONS

-21.44%

Debt to Equity

Winner

SAIA

4.26%

IONS

88.01%

Free Cash Flow Yield

Winner

SAIA

1.56%

IONS

-7.80%

P/S Ratio

Winner

SAIA

3.81

IONS

11.70

P/B Ratio

Winner

SAIA

4.54

IONS

25.24

SAIA vs IONS - Historical Returns

Returns include dividend reinvestment.

Period	SAIA	IONS
1 month	+5.30%	+5.32%
3 months	+15.77%	-5.62%
6 months	+67.42%	-8.02%
1 year	+70.14%	+128.30%
5 years(CAGR)	+15.63%	+16.45%
10 years(CAGR)	+33.55%	+13.55%
Max(CAGR)	+18.18%	+7.64%

SAIA

+5.30%

Winner

IONS

+5.32%

Winner

SAIA

+15.77%

IONS

-5.62%

Winner

SAIA

+67.42%

IONS

-8.02%

SAIA

+70.14%

Winner

IONS

+128.30%

5Y(CAGR)

SAIA

+15.63%

Winner

IONS

+16.45%

10Y(CAGR)

Winner

SAIA

+33.55%

IONS

+13.55%

Max(CAGR)

Winner

SAIA

+18.18%

IONS

+7.64%

SAIA vs IONS - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	SAIA	IONS
2026	+38.77%	-4.52%
2025	-26.68%	+128.05%
2024	+6.60%	-33.88%
2023	+110.07%	+34.62%
2022	-33.39%	+15.86%
2021	+87.31%	-46.41%
2020	+92.77%	-7.14%
2019	+70.74%	+12.35%
2018	-21.93%	+9.77%
2017	+57.57%	+6.25%
2016	+102.62%	-22.45%
2015	-60.06%	+0.58%
2014	+81.39%	+54.85%
2013	+104.14%	+268.21%
2012	+76.09%	+44.00%
2011	-25.36%	-29.93%
2010	+15.45%	-10.20%
2009	+31.73%	-23.22%
2008	-14.82%	-7.80%
2007	-43.95%	+44.10%
2006	+4.08%	+111.81%
2005	-7.29%	-9.66%
2004	+34.62%	-13.36%
2003	+73.03%	-4.97%
2002	-25.93%	-68.69%
2001	N/A	+130.55%
2000	N/A	+77.49%
1999	N/A	-44.34%

SAIA vs IONS Drawdown Comparison

The maximum drawdown for SAIA was -80.35%, occurring on Nov 20, 2008. Recovery took 1612 trading sessions.

The maximum drawdown for IONS was -91.43%, occurring on Mar 18, 2003. Recovery took 3357 trading sessions.

The current SAIA drawdown is -22.78%. The current IONS drawdown is -12.06%.

Rank	SAIA	IONS
#1	-80.35% Oct 16, 2006 - Mar 14, 2013	-91.43% Mar 6, 2000 - Jul 11, 2013
#2	-65.82% Dec 4, 2014 - Aug 31, 2017	-73.25% Mar 19, 2015 - Mar 14, 2019
#3	-60.94% Mar 6, 2024 - Apr 29, 2025	-70.39% Apr 8, 2019 - Feb 6, 2026
#4	-53.15% Nov 17, 2021 - Jul 17, 2023	-68.14% Dec 2, 1999 - Mar 1, 2000
#5	-49.18% Sep 12, 2002 - Jul 2, 2003	-61.05% Feb 21, 2014 - Dec 10, 2014
#6	-44.51% Jun 23, 2004 - Jan 25, 2006	-28.35% Jul 12, 2013 - Sep 19, 2013
#7	-39.57% Jun 12, 2018 - Sep 4, 2019	-20.89% Sep 23, 2013 - Nov 27, 2013
#8	-39.00% Oct 28, 2019 - May 26, 2020	-19.78% Jan 12, 2015 - Mar 19, 2015
#9	-24.09% Mar 15, 2006 - Aug 16, 2006	-19.45% Feb 6, 2026 - Mar 24, 2026
#10	-21.51% Sep 1, 2023 - Dec 21, 2023	-11.84% Dec 12, 2014 - Dec 19, 2014
#11	-21.10% May 7, 2021 - Aug 11, 2021	-11.49% Dec 19, 2014 - Jan 5, 2015
#12	-19.00% Sep 22, 2003 - Dec 2, 2003	-8.95% Jan 31, 2014 - Feb 13, 2014
#13	-18.30% Jul 11, 2013 - Oct 22, 2013	-8.58% Nov 11, 1999 - Nov 17, 1999
#14	-17.02% Jan 25, 2018 - May 21, 2018	-7.67% Jan 22, 2014 - Jan 31, 2014
#15	-14.17% Oct 22, 2013 - Mar 4, 2014	-7.49% Dec 23, 2013 - Jan 8, 2014