RYTM vs SPY
Comparison between Rhythm Pharmaceuticals Inc (RYTM, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).
5-Year PerformanceRYTM has outperformed SPY, delivering a return of +31.0% compared to +13.9%
RYTM vs SPY - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Market Cap / Net Assets
RYTM
$6.41B
Winner
SPY
$735B
Expense Ratio
RYTM
N/A
SPY
0.09%
Max Drawdown
RYTM
92.10%
Winner
SPY
56.47%
Sharpe Ratio
RYTM
0.84
Winner
SPY
1.71
5Y Beta
Winner
RYTM
0.93
SPY
1.00
Industry
RYTM
Biotechnology
SPY
N/A
P/E Ratio
Winner
RYTM
-30.80
SPY
28.81
Forward P/E
RYTM
N/A
SPY
22.10
PEG Ratio
RYTM
-2.53
SPY
N/A
5Y Dividends CAGR
RYTM
N/A
SPY
5.43%
5Y EPS CAGR
RYTM
17.00%
Winner
SPY
25.84%
Debt to Equity
RYTM
88.25%
Winner
SPY
34.16%
Free Cash Flow Yield
RYTM
-1.88%
SPY
N/A
P/S Ratio
RYTM
29.66
Winner
SPY
3.69
P/B Ratio
RYTM
52.51
Winner
SPY
5.54
RYTM vs SPY - Historical Returns
Returns include dividend reinvestment.
1M
RYTM
-2.09%
Winner
SPY
+4.01%
3M
RYTM
-14.27%
Winner
SPY
+7.93%
6M
RYTM
-13.60%
Winner
SPY
+12.54%
1Y
Winner
RYTM
+41.78%
SPY
+25.60%
5Y(CAGR)
Winner
RYTM
+30.97%
SPY
+13.94%
10Y(CAGR)
RYTM
+13.13%
Winner
SPY
+15.56%
Max(CAGR)
Winner
RYTM
+13.13%
SPY
+8.49%
RYTM vs SPY - Annual Returns (1999 - 2026)
Returns include dividend reinvestment.
| Year | RYTM | SPY |
|---|---|---|
| 2026 | -17.30% | +8.42% |
| 2025 | +78.19% | +18.00% |
| 2024 | +24.04% | +25.59% |
| 2023 | +60.51% | +26.72% |
| 2022 | +172.91% | -18.64% |
| 2021 | -67.13% | +30.52% |
| 2020 | +29.83% | +17.28% |
| 2019 | -15.71% | +31.09% |
| 2018 | -4.00% | -5.24% |
| 2017 | -3.13% | +20.78% |
| 2016 | N/A | +13.59% |
| 2015 | N/A | +1.31% |
| 2014 | N/A | +14.56% |
| 2013 | N/A | +29.00% |
| 2012 | N/A | +14.17% |
| 2011 | N/A | +0.85% |
| 2010 | N/A | +13.14% |
| 2009 | N/A | +22.67% |
| 2008 | N/A | -36.25% |
| 2007 | N/A | +5.32% |
| 2006 | N/A | +13.85% |
| 2005 | N/A | +5.32% |
| 2004 | N/A | +10.75% |
| 2003 | N/A | +24.18% |
| 2002 | N/A | -22.42% |
| 2001 | N/A | -10.13% |
| 2000 | N/A | -8.84% |
| 1999 | N/A | +8.61% |
RYTM vs SPY Drawdown Comparison
The maximum drawdown for RYTM was -92.10%, occurring on May 19, 2022. Recovery took 727 trading sessions.
The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.
The current RYTM drawdown is -26.17%. The current SPY drawdown is -1.27%.
| Rank | RYTM | SPY |
|---|---|---|
| #1 | -92.10% Jan 22, 2021 - Dec 12, 2023 | -55.20% Oct 9, 2007 - Aug 16, 2012 |
| #2 | -63.29% Jul 5, 2018 - Jan 21, 2021 | -47.50% Mar 24, 2000 - Oct 26, 2006 |
| #3 | -47.22% Jan 29, 2018 - Jun 1, 2018 | -33.70% Feb 19, 2020 - Aug 10, 2020 |
| #4 | -35.54% Dec 11, 2025 - Mar 27, 2026 | -24.50% Jan 3, 2022 - Dec 13, 2023 |
| #5 | -32.48% Feb 12, 2024 - Jul 16, 2024 | -19.34% Sep 20, 2018 - Apr 12, 2019 |
| #6 | -30.27% Nov 8, 2024 - Jun 6, 2025 | -18.76% Feb 19, 2025 - Jun 26, 2025 |
| #7 | -26.67% Oct 5, 2017 - Dec 1, 2017 | -13.02% Jul 20, 2015 - Apr 18, 2016 |
| #8 | -24.99% Jun 6, 2018 - Jun 26, 2018 | -10.10% Jan 26, 2018 - Aug 6, 2018 |
| #9 | -19.92% Dec 27, 2023 - Feb 9, 2024 | -9.44% Sep 2, 2020 - Nov 11, 2020 |
| #10 | -19.17% Jul 16, 2024 - Sep 19, 2024 | -9.30% Jan 19, 2000 - Mar 17, 2000 |
| #11 | -15.80% Oct 29, 2025 - Dec 11, 2025 | -9.05% Jul 19, 2007 - Oct 5, 2007 |
| #12 | -13.83% Dec 18, 2017 - Jan 25, 2018 | -8.88% Jan 27, 2026 - Apr 14, 2026 |
| #13 | -13.47% Sep 19, 2024 - Nov 5, 2024 | -8.41% Jul 16, 2024 - Sep 19, 2024 |
| #14 | -11.19% Jun 26, 2018 - Jul 3, 2018 | -7.35% Sep 14, 2012 - Jan 2, 2013 |
| #15 | -10.68% Dec 1, 2017 - Dec 18, 2017 | -7.27% Sep 18, 2014 - Oct 31, 2014 |
Correlation
Correlation between RYTM and SPY is 0.78 which considered as a strong positive correlation - the stocks tend to move together.
0.78
-101
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