RYTM vs AGNCP

Comparison between Rhythm Pharmaceuticals Inc (RYTM, Company) and AGNC Investment Corp (AGNCP, Company).

RYTM is from the Healthcare sector, while AGNCP is from the Real Estate sector.

5-Year PerformanceRYTM has outperformed AGNCP, delivering a return of +31.0% compared to +7.8%

RYTM vs AGNCP - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	RYTM(COMPANY)	AGNCP(COMPANY)
Market Cap	$6.41B	$6.42B
Max Drawdown	92.10%	60.54%
Sharpe Ratio	0.84	1.25
5Y Beta	0.93	0.08
Industry	Biotechnology	Reit - Mortgage
P/E Ratio	-30.80	N/A
PEG Ratio	-2.53	N/A
Dividend Yield	N/A	5.78%
5Y Dividends CAGR	N/A	11.70%
5Y EPS CAGR	17.00%	N/A
Debt to Equity	88.25%	N/A
Free Cash Flow Yield	-1.88%	N/A
P/S Ratio	29.66	3.90
P/B Ratio	52.51	N/A

Market Cap

RYTM

$6.41B

Winner

AGNCP

$6.42B

Max Drawdown

RYTM

92.10%

Winner

AGNCP

60.54%

Sharpe Ratio

RYTM

0.84

Winner

AGNCP

1.25

5Y Beta

RYTM

0.93

Winner

AGNCP

0.08

Industry

RYTM

Biotechnology

AGNCP

Reit - Mortgage

P/E Ratio

RYTM

-30.80

AGNCP

N/A

PEG Ratio

RYTM

-2.53

AGNCP

N/A

Dividend Yield

RYTM

N/A

AGNCP

5.78%

5Y Dividends CAGR

RYTM

N/A

AGNCP

11.70%

5Y EPS CAGR

RYTM

17.00%

AGNCP

N/A

Debt to Equity

RYTM

88.25%

AGNCP

N/A

Free Cash Flow Yield

RYTM

-1.88%

AGNCP

N/A

P/S Ratio

RYTM

29.66

Winner

AGNCP

3.90

P/B Ratio

RYTM

52.51

AGNCP

N/A

RYTM vs AGNCP - Historical Returns

Returns include dividend reinvestment.

Period	RYTM	AGNCP
1 month	-2.09%	+1.88%
3 months	-14.27%	+1.81%
6 months	-13.60%	+4.87%
1 year	+41.78%	+9.47%
5 years(CAGR)	+30.97%	+7.80%
10 years(CAGR)	+13.13%	N/A
Max(CAGR)	+13.13%	+7.34%

RYTM

-2.09%

Winner

AGNCP

+1.88%

RYTM

-14.27%

Winner

AGNCP

+1.81%

RYTM

-13.60%

Winner

AGNCP

+4.87%

Winner

RYTM

+41.78%

AGNCP

+9.47%

5Y(CAGR)

Winner

RYTM

+30.97%

AGNCP

+7.80%

10Y(CAGR)

RYTM

+13.13%

AGNCP

N/A

Max(CAGR)

Winner

RYTM

+13.13%

AGNCP

+7.34%

RYTM vs AGNCP - Annual Returns (2017 - 2026)

Returns include dividend reinvestment.

Year	RYTM	AGNCP
2026	-17.30%	+3.51%
2025	+78.19%	+8.13%
2024	+24.04%	+20.43%
2023	+60.51%	+20.28%
2022	+172.91%	-17.95%
2021	-67.13%	+13.14%
2020	+29.83%	+2.24%
2019	-15.71%	N/A
2018	-4.00%	N/A
2017	-3.13%	N/A

RYTM vs AGNCP Drawdown Comparison

The maximum drawdown for RYTM was -92.10%, occurring on May 19, 2022. Recovery took 727 trading sessions.

The maximum drawdown for AGNCP was -60.54%, occurring on Mar 18, 2020. Recovery took 217 trading sessions.

The current RYTM drawdown is -26.17%. The current AGNCP drawdown is -0.04%.

Rank	RYTM	AGNCP
#1	-92.10% Jan 22, 2021 - Dec 12, 2023	-60.54% Feb 20, 2020 - Dec 29, 2020
#2	-63.29% Jul 5, 2018 - Jan 21, 2021	-28.95% Jan 3, 2022 - Dec 22, 2023
#3	-47.22% Jan 29, 2018 - Jun 1, 2018	-5.79% Apr 1, 2025 - Jun 12, 2025
#4	-35.54% Dec 11, 2025 - Mar 27, 2026	-4.47% Jan 20, 2021 - Apr 6, 2021
#5	-32.48% Feb 12, 2024 - Jul 16, 2024	-3.62% Jan 23, 2026 - Apr 21, 2026
#6	-30.27% Nov 8, 2024 - Jun 6, 2025	-2.80% May 10, 2021 - May 18, 2021
#7	-26.67% Oct 5, 2017 - Dec 1, 2017	-2.59% Oct 14, 2021 - Dec 31, 2021
#8	-24.99% Jun 6, 2018 - Jun 26, 2018	-2.00% Mar 26, 2024 - Apr 3, 2024
#9	-19.92% Dec 27, 2023 - Feb 9, 2024	-1.88% Jul 7, 2021 - Aug 5, 2021
#10	-19.17% Jul 16, 2024 - Sep 19, 2024	-1.80% Nov 8, 2024 - Dec 31, 2024
#11	-15.80% Oct 29, 2025 - Dec 11, 2025	-1.61% Jul 19, 2024 - Aug 26, 2024
#12	-13.83% Dec 18, 2017 - Jan 25, 2018	-1.57% Aug 5, 2021 - Aug 31, 2021
#13	-13.47% Sep 19, 2024 - Nov 5, 2024	-1.53% Sep 25, 2024 - Oct 17, 2024
#14	-11.19% Jun 26, 2018 - Jul 3, 2018	-1.49% Apr 4, 2024 - May 1, 2024
#15	-10.68% Dec 1, 2017 - Dec 18, 2017	-1.48% Sep 13, 2021 - Sep 30, 2021