RNTX vs SPY

Comparison between Rein Therapeutics Inc (RNTX, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).

5-Year PerformanceSPY has outperformed RNTX, delivering a return of +13.3% compared to -48.4%

RNTX vs SPY - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	RNTX(COMPANY)	SPY(ETF)
Market Cap / Net Assets	$52M	$735B
Expense Ratio	N/A	0.09%
Max Drawdown	99.68%	56.47%
Sharpe Ratio	-0.41	1.62
5Y Beta	0.85	1.00
Industry	Biotechnology	N/A
P/E Ratio	-0.97	28.99
Forward P/E	N/A	22.37
5Y Dividends CAGR	N/A	5.43%
5Y EPS CAGR	-37.84%	26.05%
Debt to Equity	0.00%	32.40%
Free Cash Flow Yield	-37.38%	N/A
P/S Ratio	N/A	3.74
P/B Ratio	28.17	5.61

Market Cap / Net Assets

RNTX

$52M

Winner

SPY

$735B

Expense Ratio

RNTX

N/A

SPY

0.09%

Max Drawdown

RNTX

99.68%

Winner

SPY

56.47%

Sharpe Ratio

RNTX

-0.41

Winner

SPY

1.62

5Y Beta

Winner

RNTX

0.85

SPY

1.00

Industry

RNTX

Biotechnology

SPY

N/A

P/E Ratio

Winner

RNTX

-0.97

SPY

28.99

Forward P/E

RNTX

N/A

SPY

22.37

5Y Dividends CAGR

RNTX

N/A

SPY

5.43%

5Y EPS CAGR

RNTX

-37.84%

Winner

SPY

26.05%

Debt to Equity

Winner

RNTX

0.00%

SPY

32.40%

Free Cash Flow Yield

RNTX

-37.38%

SPY

N/A

P/S Ratio

RNTX

N/A

SPY

3.74

P/B Ratio

RNTX

28.17

Winner

SPY

5.61

RNTX vs SPY - Historical Returns

Returns include dividend reinvestment.

Period	RNTX	SPY
1 month	-7.54%	+1.90%
3 months	-20.75%	+8.55%
6 months	-30.65%	+8.18%
1 year	-51.64%	+25.79%
5 years(CAGR)	-48.39%	+13.32%
10 years(CAGR)	-8.30%	+15.19%
Max(CAGR)	-12.82%	+8.47%

RNTX

-7.54%

Winner

SPY

+1.90%

RNTX

-20.75%

Winner

SPY

+8.55%

RNTX

-30.65%

Winner

SPY

+8.18%

RNTX

-51.64%

Winner

SPY

+25.79%

5Y(CAGR)

RNTX

-48.39%

Winner

SPY

+13.32%

10Y(CAGR)

RNTX

-8.30%

Winner

SPY

+15.19%

Max(CAGR)

RNTX

-12.82%

Winner

SPY

+8.47%

RNTX vs SPY - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	RNTX	SPY
2026	-24.55%	+8.26%
2025	-48.44%	+18.00%
2024	-26.28%	+25.59%
2023	-4.73%	+26.72%
2022	-80.11%	-18.64%
2021	-46.39%	+30.52%
2020	+74.79%	+17.28%
2019	-43.82%	+31.09%
2018	-92.02%	-5.24%
2017	+9302.32%	+20.78%
2016	+0.00%	+13.59%
2015	+0.00%	+1.31%
2014	+0.00%	+14.56%
2013	-77.52%	+29.00%
2012	-71.66%	+14.17%
2011	-22.46%	+0.85%
2010	+215.48%	+13.14%
2009	+21.67%	+22.67%
2008	-31.03%	-36.25%
2007	-56.50%	+5.32%
2006	+12.00%	+13.85%
2005	-14.85%	+5.32%
2004	-11.90%	+10.75%
2003	+70.25%	+24.18%
2002	+1.94%	-22.42%
2001	-31.11%	-10.13%
2000	+12.12%	-8.84%
1999	+13.79%	+8.61%

RNTX vs SPY Drawdown Comparison

The maximum drawdown for RNTX was -99.68%, occurring on Jun 5, 2026. This drawdown has not yet recovered.

The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.

The current RNTX drawdown is -99.68%. The current SPY drawdown is -2.90%.

Rank	RNTX	SPY
#1	-99.68% Oct 4, 2017 - Jun 5, 2026	-55.20% Oct 9, 2007 - Aug 16, 2012
#2	-97.95% Feb 17, 2004 - Jun 29, 2017	-47.50% Mar 24, 2000 - Oct 26, 2006
#3	-64.00% Mar 20, 2000 - Feb 9, 2004	-33.70% Feb 19, 2020 - Aug 10, 2020
#4	-26.17% Jan 4, 2000 - Mar 14, 2000	-24.50% Jan 3, 2022 - Dec 13, 2023
#5	-18.78% Sep 7, 2017 - Oct 2, 2017	-19.34% Sep 20, 2018 - Apr 12, 2019
#6	-17.25% Jul 7, 2017 - Sep 7, 2017	-18.76% Feb 19, 2025 - Jun 26, 2025
#7	-16.15% Nov 2, 1999 - Nov 12, 1999	-13.02% Jul 20, 2015 - Apr 18, 2016
#8	-13.14% Dec 21, 1999 - Jan 4, 2000	-10.10% Jan 26, 2018 - Aug 6, 2018
#9	-11.43% Nov 22, 1999 - Dec 3, 1999	-9.44% Sep 2, 2020 - Nov 11, 2020
#10	-10.81% Dec 9, 1999 - Dec 21, 1999	-9.30% Jan 19, 2000 - Mar 17, 2000
#11	-3.85% Mar 14, 2000 - Mar 17, 2000	-9.05% Jul 19, 2007 - Oct 5, 2007
#12	-3.05% Nov 15, 1999 - Nov 22, 1999	-8.88% Jan 27, 2026 - Apr 14, 2026
#13	-2.53% Feb 10, 2004 - Feb 17, 2004	-8.41% Jul 16, 2024 - Sep 19, 2024
#14	-2.30% Jul 3, 2017 - Jul 6, 2017	-7.35% Sep 14, 2012 - Jan 2, 2013
#15	-0.07% Oct 2, 2017 - Oct 4, 2017	-7.27% Sep 18, 2014 - Oct 31, 2014

Correlation

Correlation between RNTX and SPY is -0.20 which considered as a very weak or no correlation - the stocks move independently of each other.

-0.20

-101

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RNTX vs SPY

RNTX vs SPY - Performance Comparison

Key Characteristics

RNTX vs SPY - Historical Returns

RNTX vs SPY - Annual Returns (1999 - 2026)

RNTX vs SPY Drawdown Comparison

Correlation

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