RGLS vs TMQ

Comparison between Regulus Therapeutics Inc (RGLS, Company) and Trilogy Metals Inc (TMQ, Company).

5-Year PerformanceTMQ has outperformed RGLS, delivering a return of +7.7% compared to +0.4%

RGLS vs TMQ - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	RGLS(COMPANY)	TMQ(COMPANY)
Market Cap	$540M	$542M
Max Drawdown	99.97%	96.55%
Sharpe Ratio	1.24	0.83
5Y Beta	N/A	1.44
Industry	N/A	Other Industrial Metals & Mining
P/E Ratio	-10.76	-30.87
PEG Ratio	N/A	-0.57
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-8.08%	-1.03%
P/S Ratio	0.57	N/A
P/B Ratio	7.82	4.78

Market Cap

RGLS

$540M

Winner

TMQ

$542M

Max Drawdown

RGLS

99.97%

Winner

TMQ

96.55%

Sharpe Ratio

Winner

RGLS

1.24

TMQ

0.83

5Y Beta

RGLS

N/A

TMQ

1.44

Industry

RGLS

N/A

TMQ

Other Industrial Metals & Mining

P/E Ratio

RGLS

-10.76

Winner

TMQ

-30.87

PEG Ratio

RGLS

N/A

TMQ

-0.57

Debt to Equity

RGLS

0.00%

TMQ

0.00%

Free Cash Flow Yield

RGLS

-8.08%

Winner

TMQ

-1.03%

P/S Ratio

RGLS

0.57

TMQ

N/A

P/B Ratio

RGLS

7.82

Winner

TMQ

4.78

RGLS vs TMQ - Historical Returns

Returns include dividend reinvestment.

Period	RGLS	TMQ
1 month	+3.42%	-13.78%
3 months	+527.69%	-27.17%
6 months	+429.87%	-41.79%
1 year	+281.31%	+65.28%
5 years(CAGR)	+0.40%	+7.72%
10 years(CAGR)	-39.42%	+18.39%
Max(CAGR)	-27.95%	-2.71%

Winner

RGLS

+3.42%

TMQ

-13.78%

Winner

RGLS

+527.69%

TMQ

-27.17%

Winner

RGLS

+429.87%

TMQ

-41.79%

Winner

RGLS

+281.31%

TMQ

+65.28%

5Y(CAGR)

RGLS

+0.40%

Winner

TMQ

+7.72%

10Y(CAGR)

RGLS

-39.42%

Winner

TMQ

+18.39%

Max(CAGR)

RGLS

-27.95%

Winner

TMQ

-2.71%

RGLS vs TMQ - Annual Returns (2012 - 2026)

Returns include dividend reinvestment.

Year	RGLS	TMQ
2026	N/A	-30.50%
2025	+423.08%	+262.18%
2024	+20.61%	+171.28%
2023	-5.88%	-24.56%
2022	-58.23%	-67.65%
2021	-75.77%	-17.91%
2020	+33.66%	-23.37%
2019	-19.82%	+44.44%
2018	-93.14%	+46.61%
2017	-54.78%	+114.61%
2016	-73.75%	+83.67%
2015	-49.27%	-48.99%
2014	+117.93%	-67.97%
2013	+15.65%	-23.62%
2012	+43.84%	-61.65%

RGLS vs TMQ Drawdown Comparison

The maximum drawdown for RGLS was -99.97%, occurring on Mar 27, 2023. This drawdown has not yet recovered.

The maximum drawdown for TMQ was -96.55%, occurring on Jan 20, 2016. Recovery took 3382 trading sessions.

The current RGLS drawdown is -99.69%. The current TMQ drawdown is -69.91%.

Rank	RGLS	TMQ
#1	-99.97% Nov 7, 2014 - Mar 27, 2023	-96.55% Apr 25, 2012 - Oct 7, 2025
#2	-53.26% Jul 11, 2013 - Oct 22, 2014	-71.98% Oct 14, 2025 - Jul 16, 2026
#3	-25.98% Jan 2, 2013 - Mar 13, 2013	-9.47% Oct 9, 2025 - Oct 13, 2025
#4	-16.39% Mar 28, 2013 - May 29, 2013	-2.92% Oct 7, 2025 - Oct 9, 2025
#5	-15.76% Oct 25, 2012 - Dec 19, 2012	N/A
#6	-10.59% Jun 21, 2013 - Jul 2, 2013	N/A
#7	-6.27% Nov 4, 2014 - Nov 7, 2014	N/A
#8	-5.25% Oct 9, 2012 - Oct 18, 2012	N/A
#9	-4.66% Oct 27, 2014 - Oct 31, 2014	N/A
#10	-4.43% Mar 20, 2013 - Mar 22, 2013	N/A
#11	-1.99% Jun 13, 2013 - Jun 20, 2013	N/A
#12	-1.62% Jun 3, 2013 - Jun 10, 2013	N/A
#13	-0.96% Dec 20, 2012 - Dec 27, 2012	N/A
#14	-0.74% Mar 15, 2013 - Mar 20, 2013	N/A
#15	-0.31% Mar 13, 2013 - Mar 15, 2013	N/A