RGEN vs SPY
Comparison between Repligen Corp (RGEN, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).
5-Year PerformanceSPY has outperformed RGEN, delivering a return of +13.9% compared to -9.5%
RGEN vs SPY - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Market Cap / Net Assets
RGEN
$6.04B
Winner
SPY
$735B
Expense Ratio
RGEN
N/A
SPY
0.09%
Max Drawdown
RGEN
92.06%
Winner
SPY
56.47%
Sharpe Ratio
RGEN
-0.24
Winner
SPY
1.71
5Y Beta
RGEN
1.39
Winner
SPY
1.00
Industry
RGEN
Medical Instruments & Supplies
SPY
N/A
P/E Ratio
RGEN
117.25
Winner
SPY
28.81
Forward P/E
RGEN
62.50
Winner
SPY
22.10
PEG Ratio
RGEN
0.45
SPY
N/A
5Y Dividends CAGR
RGEN
N/A
SPY
5.43%
5Y EPS CAGR
RGEN
9.09%
Winner
SPY
25.84%
Debt to Equity
Winner
RGEN
25.96%
SPY
34.16%
Free Cash Flow Yield
RGEN
1.76%
SPY
N/A
P/S Ratio
RGEN
7.91
Winner
SPY
3.69
P/B Ratio
Winner
RGEN
3.31
SPY
5.54
RGEN vs SPY - Historical Returns
Returns include dividend reinvestment.
1M
RGEN
-20.59%
Winner
SPY
+4.01%
3M
RGEN
-24.55%
Winner
SPY
+7.93%
6M
RGEN
-31.92%
Winner
SPY
+12.54%
1Y
RGEN
-17.43%
Winner
SPY
+25.60%
5Y(CAGR)
RGEN
-9.54%
Winner
SPY
+13.94%
10Y(CAGR)
RGEN
+14.81%
Winner
SPY
+15.56%
Max(CAGR)
Winner
RGEN
+14.04%
SPY
+8.49%
RGEN vs SPY - Annual Returns (1999 - 2026)
Returns include dividend reinvestment.
| Year | RGEN | SPY |
|---|---|---|
| 2026 | -36.60% | +8.42% |
| 2025 | +14.55% | +18.00% |
| 2024 | -19.72% | +25.59% |
| 2023 | +10.99% | +26.72% |
| 2022 | -34.37% | -18.64% |
| 2021 | +38.91% | +30.52% |
| 2020 | +104.34% | +17.28% |
| 2019 | +78.95% | +31.09% |
| 2018 | +42.31% | -5.24% |
| 2017 | +16.47% | +20.78% |
| 2016 | +9.68% | +13.59% |
| 2015 | +40.75% | +1.31% |
| 2014 | +56.77% | +14.56% |
| 2013 | +105.73% | +29.00% |
| 2012 | +79.43% | +14.17% |
| 2011 | -23.23% | +0.85% |
| 2010 | +16.09% | +13.14% |
| 2009 | +4.85% | +22.67% |
| 2008 | -43.16% | -36.25% |
| 2007 | +133.93% | +5.32% |
| 2006 | -27.95% | +13.85% |
| 2005 | +37.93% | +5.32% |
| 2004 | -30.77% | +10.75% |
| 2003 | +47.14% | +24.18% |
| 2002 | +13.01% | -22.42% |
| 2001 | -31.63% | -10.13% |
| 2000 | +10.19% | -8.84% |
| 1999 | -1.98% | +8.61% |
RGEN vs SPY Drawdown Comparison
The maximum drawdown for RGEN was -92.06%, occurring on Jul 23, 2004. Recovery took 3565 trading sessions.
The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.
The current RGEN drawdown is -67.86%. The current SPY drawdown is -1.27%.
| Rank | RGEN | SPY |
|---|---|---|
| #1 | -92.06% Mar 3, 2000 - May 7, 2014 | -55.20% Oct 9, 2007 - Aug 16, 2012 |
| #2 | -68.27% Sep 23, 2021 - May 15, 2026 | -47.50% Mar 24, 2000 - Oct 26, 2006 |
| #3 | -50.33% Jul 7, 2015 - Jun 23, 2017 | -33.70% Feb 19, 2020 - Aug 10, 2020 |
| #4 | -39.47% Nov 18, 1999 - Jan 24, 2000 | -24.50% Jan 3, 2022 - Dec 13, 2023 |
| #5 | -32.87% Sep 18, 2017 - Jun 22, 2018 | -19.34% Sep 20, 2018 - Apr 12, 2019 |
| #6 | -29.94% Nov 8, 2018 - Apr 26, 2019 | -18.76% Feb 19, 2025 - Jun 26, 2025 |
| #7 | -26.69% Feb 12, 2021 - Jul 27, 2021 | -13.02% Jul 20, 2015 - Apr 18, 2016 |
| #8 | -26.06% Feb 18, 2000 - Mar 1, 2000 | -10.10% Jan 26, 2018 - Aug 6, 2018 |
| #9 | -24.16% Jul 14, 2014 - Oct 28, 2014 | -9.44% Sep 2, 2020 - Nov 11, 2020 |
| #10 | -23.73% Oct 30, 2014 - Jan 16, 2015 | -9.30% Jan 19, 2000 - Mar 17, 2000 |
| #11 | -22.69% Aug 1, 2019 - Jan 9, 2020 | -9.05% Jul 19, 2007 - Oct 5, 2007 |
| #12 | -22.16% Feb 19, 2020 - Apr 22, 2020 | -8.88% Jan 27, 2026 - Apr 14, 2026 |
| #13 | -19.46% May 15, 2020 - Jul 30, 2020 | -8.41% Jul 16, 2024 - Sep 19, 2024 |
| #14 | -17.65% Feb 10, 2000 - Feb 15, 2000 | -7.35% Sep 14, 2012 - Jan 2, 2013 |
| #15 | -15.69% Jan 19, 2021 - Feb 11, 2021 | -7.27% Sep 18, 2014 - Oct 31, 2014 |
Correlation
Correlation between RGEN and SPY is 0.85 which considered as a strong positive correlation - the stocks tend to move together.
0.85
-101
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