RGEN vs PCVX

Comparison between Repligen Corp (RGEN, Company) and Vaxcyte Inc (PCVX, Company).

Both RGEN and PCVX are from the Healthcare sector.

5-Year PerformancePCVX has outperformed RGEN, delivering a return of +19.1% compared to -7.7%

RGEN vs PCVX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	RGEN(COMPANY)	PCVX(COMPANY)
Market Cap	$7.45B	$7.42B
Max Drawdown	92.06%	76.22%
Sharpe Ratio	0.33	1.07
5Y Beta	1.35	0.75
Industry	Medical Instruments & Supplies	Biotechnology
P/E Ratio	144.62	-7.33
Forward P/E	67.57	N/A
PEG Ratio	0.56	-0.11
5Y EPS CAGR	9.09%	33.90%
Debt to Equity	25.96%	0.00%
Free Cash Flow Yield	1.42%	-10.51%

Market Cap

Winner

RGEN

$7.45B

PCVX

$7.42B

Max Drawdown

RGEN

92.06%

Winner

PCVX

76.22%

Sharpe Ratio

RGEN

0.33

Winner

PCVX

1.07

5Y Beta

RGEN

1.35

Winner

PCVX

0.75

Industry

RGEN

Medical Instruments & Supplies

PCVX

Biotechnology

P/E Ratio

RGEN

144.62

Winner

PCVX

-7.33

Forward P/E

RGEN

67.57

PCVX

N/A

PEG Ratio

RGEN

0.56

Winner

PCVX

-0.11

5Y EPS CAGR

RGEN

9.09%

Winner

PCVX

33.90%

Debt to Equity

RGEN

25.96%

Winner

PCVX

0.00%

Free Cash Flow Yield

Winner

RGEN

1.42%

PCVX

-10.51%

RGEN vs PCVX - Historical Returns

Returns include dividend reinvestment.

Period	RGEN	PCVX
1 month	+26.70%	+6.19%
3 months	+12.27%	-5.23%
6 months	-16.29%	+17.68%
1 year	+12.32%	+54.01%
5 years(CAGR)	-7.73%	+19.09%
10 years(CAGR)	+20.09%	N/A
Max(CAGR)	+15.01%	+11.90%

Winner

RGEN

+26.70%

PCVX

+6.19%

Winner

RGEN

+12.27%

PCVX

-5.23%

RGEN

-16.29%

Winner

PCVX

+17.68%

RGEN

+12.32%

Winner

PCVX

+54.01%

5Y(CAGR)

RGEN

-7.73%

Winner

PCVX

+19.09%

10Y(CAGR)

RGEN

+20.09%

PCVX

N/A

Max(CAGR)

Winner

RGEN

+15.01%

PCVX

+11.90%

RGEN vs PCVX - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	RGEN	PCVX
2026	-19.67%	+10.72%
2025	+14.55%	-44.61%
2024	-19.72%	+30.06%
2023	+10.99%	+33.05%
2022	-34.37%	+82.46%
2021	+38.91%	-11.92%
2020	+104.34%	+1.61%
2019	+78.95%	N/A
2018	+42.31%	N/A
2017	+16.47%	N/A
2016	+9.68%	N/A
2015	+40.75%	N/A
2014	+56.77%	N/A
2013	+105.73%	N/A
2012	+79.43%	N/A
2011	-23.23%	N/A
2010	+16.09%	N/A
2009	+4.85%	N/A
2008	-43.16%	N/A
2007	+133.93%	N/A
2006	-27.95%	N/A
2005	+37.93%	N/A
2004	-30.77%	N/A
2003	+47.14%	N/A
2002	+13.01%	N/A
2001	-31.63%	N/A
2000	+10.19%	N/A
1999	-1.98%	N/A

RGEN vs PCVX Drawdown Comparison

The maximum drawdown for RGEN was -92.06%, occurring on Jul 23, 2004. Recovery took 3565 trading sessions.

The maximum drawdown for PCVX was -76.22%, occurring on Apr 10, 2025. This drawdown has not yet recovered.

The current RGEN drawdown is -59.28%. The current PCVX drawdown is -56.38%.

Rank	RGEN	PCVX
#1	-92.06% Mar 3, 2000 - May 7, 2014	-76.22% Oct 16, 2024 - Apr 10, 2025
#2	-68.27% Sep 23, 2021 - May 15, 2026	-70.31% Sep 23, 2020 - Dec 6, 2023
#3	-50.33% Jul 7, 2015 - Jun 23, 2017	-33.91% Aug 20, 2020 - Sep 22, 2020
#4	-39.47% Nov 18, 1999 - Jan 24, 2000	-25.90% Feb 27, 2024 - Jul 11, 2024
#5	-32.87% Sep 18, 2017 - Jun 22, 2018	-25.25% Jun 19, 2020 - Aug 10, 2020
#6	-29.94% Nov 8, 2018 - Apr 26, 2019	-17.19% Jul 24, 2024 - Sep 3, 2024
#7	-26.69% Feb 12, 2021 - Jul 27, 2021	-7.39% Sep 19, 2024 - Oct 16, 2024
#8	-26.06% Feb 18, 2000 - Mar 1, 2000	-7.07% Jan 4, 2024 - Jan 23, 2024
#9	-24.16% Jul 14, 2014 - Oct 28, 2014	-5.48% Jul 15, 2024 - Jul 24, 2024
#10	-23.73% Oct 30, 2014 - Jan 16, 2015	-5.43% Feb 12, 2024 - Feb 23, 2024
#11	-22.69% Aug 1, 2019 - Jan 9, 2020	-3.10% Dec 19, 2023 - Dec 26, 2023
#12	-22.16% Feb 19, 2020 - Apr 22, 2020	-2.90% Jan 23, 2024 - Jan 29, 2024
#13	-19.46% May 15, 2020 - Jul 30, 2020	-2.74% Feb 1, 2024 - Feb 12, 2024
#14	-17.65% Feb 10, 2000 - Feb 15, 2000	-2.66% Aug 14, 2020 - Aug 19, 2020
#15	-15.69% Jan 19, 2021 - Feb 11, 2021	-2.65% Aug 10, 2020 - Aug 12, 2020

Correlation

Correlation between RGEN and PCVX is -0.43 which considered as a weak negative correlation - the stocks show a slight tendency to move in opposite directions.

-0.43

-101