RGEN vs KMX

Comparison between Repligen Corp (RGEN, Company) and Carmax Inc (KMX, Company).

RGEN is from the Healthcare sector, while KMX is from the Consumer Cyclical sector.

5-Year PerformanceRGEN has outperformed KMX, delivering a return of -5.6% compared to -14.8%

RGEN vs KMX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	RGEN(COMPANY)	KMX(COMPANY)
Market Cap	$8.35B	$8.36B
Max Drawdown	92.06%	80.06%
Sharpe Ratio	0.58	0.04
5Y Beta	1.33	1.19
Industry	Medical Instruments & Supplies	Auto & Truck Dealerships
P/E Ratio	162.20	38.33
Forward P/E	73.53	21.93
PEG Ratio	0.62	N/A
5Y EPS CAGR	9.09%	-26.60%
Debt to Equity	25.96%	287.29%
Free Cash Flow Yield	1.27%	11.89%

Market Cap

RGEN

$8.35B

Winner

KMX

$8.36B

Max Drawdown

RGEN

92.06%

Winner

KMX

80.06%

Sharpe Ratio

Winner

RGEN

0.58

KMX

0.04

5Y Beta

RGEN

1.33

Winner

KMX

1.19

Industry

RGEN

Medical Instruments & Supplies

KMX

Auto & Truck Dealerships

P/E Ratio

RGEN

162.20

Winner

KMX

38.33

Forward P/E

RGEN

73.53

Winner

KMX

21.93

PEG Ratio

RGEN

0.62

KMX

N/A

5Y EPS CAGR

Winner

RGEN

9.09%

KMX

-26.60%

Debt to Equity

Winner

RGEN

25.96%

KMX

287.29%

Free Cash Flow Yield

RGEN

1.27%

Winner

KMX

11.89%

RGEN vs KMX - Historical Returns

Returns include dividend reinvestment.

Period	RGEN	KMX
1 month	+13.14%	+12.89%
3 months	+12.23%	+45.49%
6 months	-8.43%	+21.48%
1 year	+25.37%	-6.41%
5 years(CAGR)	-5.56%	-14.80%
10 years(CAGR)	+18.53%	+0.65%
Max(CAGR)	+15.46%	+14.92%

Winner

RGEN

+13.14%

KMX

+12.89%

RGEN

+12.23%

Winner

KMX

+45.49%

RGEN

-8.43%

Winner

KMX

+21.48%

Winner

RGEN

+25.37%

KMX

-6.41%

5Y(CAGR)

Winner

RGEN

-5.56%

KMX

-14.80%

10Y(CAGR)

Winner

RGEN

+18.53%

KMX

+0.65%

Max(CAGR)

Winner

RGEN

+15.46%

KMX

+14.92%

RGEN vs KMX - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	RGEN	KMX
2026	-9.91%	+50.01%
2025	+14.55%	-52.43%
2024	-19.72%	+7.30%
2023	+10.99%	+26.55%
2022	-34.37%	-52.06%
2021	+38.91%	+39.58%
2020	+104.34%	+5.53%
2019	+78.95%	+39.23%
2018	+42.31%	-3.13%
2017	+16.47%	-1.06%
2016	+9.68%	+22.95%
2015	+40.75%	-18.81%
2014	+56.77%	+41.96%
2013	+105.73%	+24.66%
2012	+79.43%	+23.00%
2011	-23.23%	-5.93%
2010	+16.09%	+32.94%
2009	+4.85%	+191.47%
2008	-43.16%	-60.74%
2007	+133.93%	-28.56%
2006	-27.95%	+87.71%
2005	+37.93%	-8.34%
2004	-30.77%	+1.87%
2003	+47.14%	+73.08%
2002	+13.01%	-20.36%
2001	-31.63%	+468.50%
2000	+10.19%	+75.02%
1999	-1.98%	-19.55%

RGEN vs KMX Drawdown Comparison

The maximum drawdown for RGEN was -92.06%, occurring on Jul 23, 2004. Recovery took 3565 trading sessions.

The maximum drawdown for KMX was -80.06%, occurring on Nov 6, 2025. This drawdown has not yet recovered.

The current RGEN drawdown is -54.33%. The current KMX drawdown is -61.94%.

Rank	RGEN	KMX
#1	-92.06% Mar 3, 2000 - May 7, 2014	-80.06% Nov 9, 2021 - Nov 6, 2025
#2	-68.27% Sep 23, 2021 - May 15, 2026	-78.70% Jan 24, 2007 - Oct 8, 2010
#3	-50.33% Jul 7, 2015 - Jun 23, 2017	-62.01% May 9, 2002 - Jul 11, 2003
#4	-39.47% Nov 18, 1999 - Jan 24, 2000	-56.56% Feb 20, 2020 - Aug 10, 2020
#5	-32.87% Sep 18, 2017 - Jun 22, 2018	-53.98% Dec 2, 1999 - Mar 27, 2000
#6	-29.94% Nov 8, 2018 - Apr 26, 2019	-52.99% Oct 14, 2003 - Sep 12, 2006
#7	-26.69% Feb 12, 2021 - Jul 27, 2021	-51.20% Jul 18, 2001 - Nov 6, 2001
#8	-26.06% Feb 18, 2000 - Mar 1, 2000	-43.60% Apr 2, 2015 - Sep 27, 2017
#9	-24.16% Jul 14, 2014 - Oct 28, 2014	-43.54% Mar 28, 2000 - Aug 2, 2000
#10	-23.73% Oct 30, 2014 - Jan 16, 2015	-36.44% Feb 18, 2011 - Dec 20, 2012
#11	-22.69% Aug 1, 2019 - Jan 9, 2020	-34.12% Sep 7, 2000 - Feb 13, 2001
#12	-22.16% Feb 19, 2020 - Apr 22, 2020	-29.70% Sep 12, 2018 - Jun 10, 2019
#13	-19.46% May 15, 2020 - Jul 30, 2020	-23.49% Oct 6, 2017 - Jun 22, 2018
#14	-17.65% Feb 10, 2000 - Feb 15, 2000	-22.29% Jun 4, 2001 - Jul 17, 2001
#15	-15.69% Jan 19, 2021 - Feb 11, 2021	-20.55% Aug 24, 2020 - Jan 19, 2021