RGEN vs GKOS

Comparison between Repligen Corp (RGEN, Company) and Glaukos Corporation (GKOS, Company).

Both RGEN and GKOS are from the Healthcare sector.

5-Year PerformanceGKOS has outperformed RGEN, delivering a return of +7.0% compared to -7.5%

RGEN vs GKOS - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	RGEN(COMPANY)	GKOS(COMPANY)
Market Cap	$6.38B	$6.41B
Max Drawdown	92.06%	69.57%
Sharpe Ratio	0.19	0.34
5Y Beta	1.39	1.36
Industry	Medical Instruments & Supplies	Medical Devices
P/E Ratio	123.98	-33.41
Forward P/E	57.14	2000.00
PEG Ratio	0.48	-0.70
5Y EPS CAGR	9.09%	12.32%
Debt to Equity	25.96%	0.00%
Free Cash Flow Yield	1.66%	-0.29%
P/S Ratio	8.36	11.63
P/B Ratio	3.03	9.62

Market Cap

RGEN

$6.38B

Winner

GKOS

$6.41B

Max Drawdown

RGEN

92.06%

Winner

GKOS

69.57%

Sharpe Ratio

RGEN

0.19

Winner

GKOS

0.34

5Y Beta

RGEN

1.39

Winner

GKOS

1.36

Industry

RGEN

Medical Instruments & Supplies

GKOS

Medical Devices

P/E Ratio

RGEN

123.98

Winner

GKOS

-33.41

Forward P/E

Winner

RGEN

57.14

GKOS

2000.00

PEG Ratio

RGEN

0.48

Winner

GKOS

-0.70

5Y EPS CAGR

RGEN

9.09%

Winner

GKOS

12.32%

Debt to Equity

RGEN

25.96%

Winner

GKOS

0.00%

Free Cash Flow Yield

Winner

RGEN

1.66%

GKOS

-0.29%

P/S Ratio

Winner

RGEN

8.36

GKOS

11.63

P/B Ratio

Winner

RGEN

3.03

GKOS

9.62

RGEN vs GKOS - Historical Returns

Returns include dividend reinvestment.

Period	RGEN	GKOS
1 month	+9.58%	-11.65%
3 months	-0.82%	-14.68%
6 months	-27.52%	-2.78%
1 year	+1.33%	+8.93%
5 years(CAGR)	-7.45%	+7.03%
10 years(CAGR)	+17.72%	+15.54%
Max(CAGR)	+14.77%	+11.58%

Winner

RGEN

+9.58%

GKOS

-11.65%

Winner

RGEN

-0.82%

GKOS

-14.68%

RGEN

-27.52%

Winner

GKOS

-2.78%

RGEN

+1.33%

Winner

GKOS

+8.93%

5Y(CAGR)

RGEN

-7.45%

Winner

GKOS

+7.03%

10Y(CAGR)

Winner

RGEN

+17.72%

GKOS

+15.54%

Max(CAGR)

Winner

RGEN

+14.77%

GKOS

+11.58%

RGEN vs GKOS - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	RGEN	GKOS
2026	-24.58%	-6.67%
2025	+14.55%	-24.57%
2024	-19.72%	+94.53%
2023	+10.99%	+81.15%
2022	-34.37%	-7.89%
2021	+38.91%	-36.90%
2020	+104.34%	+38.27%
2019	+78.95%	+1.34%
2018	+42.31%	+107.42%
2017	+16.47%	-23.93%
2016	+9.68%	+43.82%
2015	+40.75%	-20.92%
2014	+56.77%	N/A
2013	+105.73%	N/A
2012	+79.43%	N/A
2011	-23.23%	N/A
2010	+16.09%	N/A
2009	+4.85%	N/A
2008	-43.16%	N/A
2007	+133.93%	N/A
2006	-27.95%	N/A
2005	+37.93%	N/A
2004	-30.77%	N/A
2003	+47.14%	N/A
2002	+13.01%	N/A
2001	-31.63%	N/A
2000	+10.19%	N/A
1999	-1.98%	N/A

RGEN vs GKOS Drawdown Comparison

The maximum drawdown for RGEN was -92.06%, occurring on Jul 23, 2004. Recovery took 3565 trading sessions.

The maximum drawdown for GKOS was -69.57%, occurring on Mar 20, 2020. Recovery took 366 trading sessions.

The current RGEN drawdown is -61.77%. The current GKOS drawdown is -35.90%.

Rank	RGEN	GKOS
#1	-92.06% Mar 3, 2000 - May 7, 2014	-69.57% Aug 1, 2019 - Jan 13, 2021
#2	-68.27% Sep 23, 2021 - May 15, 2026	-64.32% Apr 28, 2021 - Apr 8, 2024
#3	-50.33% Jul 7, 2015 - Jun 23, 2017	-55.00% Aug 18, 2015 - Jul 21, 2016
#4	-39.47% Nov 18, 1999 - Jan 24, 2000	-53.68% Jan 23, 2025 - Oct 24, 2025
#5	-32.87% Sep 18, 2017 - Jun 22, 2018	-53.09% Apr 3, 2017 - Aug 29, 2018
#6	-29.94% Nov 8, 2018 - Apr 26, 2019	-25.77% Aug 31, 2018 - Feb 12, 2019
#7	-26.69% Feb 12, 2021 - Jul 27, 2021	-22.03% Sep 27, 2016 - Jan 12, 2017
#8	-26.06% Feb 18, 2000 - Mar 1, 2000	-21.05% Mar 21, 2019 - Jul 31, 2019
#9	-24.16% Jul 14, 2014 - Oct 28, 2014	-17.93% Mar 1, 2021 - Apr 28, 2021
#10	-23.73% Oct 30, 2014 - Jan 16, 2015	-17.27% Jul 27, 2016 - Sep 14, 2016
#11	-22.69% Aug 1, 2019 - Jan 9, 2020	-11.05% Mar 2, 2017 - Mar 16, 2017
#12	-22.16% Feb 19, 2020 - Apr 22, 2020	-10.99% Feb 28, 2019 - Mar 19, 2019
#13	-19.46% May 15, 2020 - Jul 30, 2020	-10.31% Jun 25, 2015 - Jul 17, 2015
#14	-17.65% Feb 10, 2000 - Feb 15, 2000	-10.20% Aug 28, 2024 - Oct 29, 2024
#15	-15.69% Jan 19, 2021 - Feb 11, 2021	-9.60% Jul 16, 2024 - Aug 16, 2024