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QTTB vs SPY

Comparison between Q32 Bio Inc (QTTB, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).

5-Year PerformanceSPY has outperformed QTTB, delivering a return of +13.4% compared to -37.2%

QTTB vs SPY - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap / Net Assets
QTTB
$188M
Winner
SPY
$784B
Expense Ratio
QTTB
N/A
SPY
0.09%
Max Drawdown
QTTB
99.75%
Winner
SPY
56.47%
Sharpe Ratio
Winner
QTTB
1.74
SPY
1.56
5Y Beta
Winner
QTTB
0.82
SPY
1.00
Industry
QTTB
Biotechnology
SPY
N/A
P/E Ratio
Winner
QTTB
-4.59
SPY
28.29
Forward P/E
QTTB
N/A
SPY
21.75
5Y Dividends CAGR
QTTB
N/A
SPY
5.43%
5Y EPS CAGR
QTTB
-43.57%
Winner
SPY
25.98%
Debt to Equity
Winner
QTTB
0.00%
SPY
30.79%
Free Cash Flow Yield
QTTB
-14.55%
SPY
N/A
P/S Ratio
QTTB
4.06
Winner
SPY
3.79
P/B Ratio
Winner
QTTB
4.71
SPY
5.67

QTTB vs SPY - Historical Returns

Returns include dividend reinvestment.

1M
Winner
QTTB
+117.56%
SPY
+0.48%
3M
Winner
QTTB
+79.55%
SPY
+11.67%
6M
Winner
QTTB
+327.03%
SPY
+9.42%
1Y
Winner
QTTB
+643.53%
SPY
+24.27%
5Y(CAGR)
QTTB
-37.15%
Winner
SPY
+13.36%
10Y(CAGR)
QTTB
-32.94%
Winner
SPY
+15.42%
Max(CAGR)
QTTB
-32.94%
Winner
SPY
+8.49%

QTTB vs SPY - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

YearQTTBSPY
2026+267.44%+8.88%
2025-3.77%+18.00%
2024-68.32%+25.59%
2023-49.33%+26.72%
2022-69.78%-18.64%
2021-68.73%+30.52%
2020-45.01%+17.28%
2019-15.54%+31.09%
2018+19.83%-5.24%
2017N/A+20.78%
2016N/A+13.59%
2015N/A+1.31%
2014N/A+14.56%
2013N/A+29.00%
2012N/A+14.17%
2011N/A+0.85%
2010N/A+13.14%
2009N/A+22.67%
2008N/A-36.25%
2007N/A+5.32%
2006N/A+13.85%
2005N/A+5.32%
2004N/A+10.75%
2003N/A+24.18%
2002N/A-22.42%
2001N/A-10.13%
2000N/A-8.84%
1999N/A+8.61%

QTTB vs SPY Drawdown Comparison

The maximum drawdown for QTTB was -99.75%, occurring on Jul 7, 2025. This drawdown has not yet recovered.

The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.

The current QTTB drawdown is -97.69%. The current SPY drawdown is -2.35%.

RankQTTBSPY
#1-99.75%
Apr 5, 2019 - Jul 7, 2025		-55.20%
Oct 9, 2007 - Aug 16, 2012
#2-30.90%
Jul 10, 2018 - Sep 24, 2018		-47.50%
Mar 24, 2000 - Oct 26, 2006
#3-25.93%
Dec 10, 2018 - Feb 25, 2019		-33.70%
Feb 19, 2020 - Aug 10, 2020
#4-19.55%
Sep 28, 2018 - Dec 3, 2018		-24.50%
Jan 3, 2022 - Dec 13, 2023
#5-13.41%
May 4, 2018 - Jul 9, 2018		-19.34%
Sep 20, 2018 - Apr 12, 2019
#6-12.88%
Feb 27, 2019 - Apr 5, 2019		-18.76%
Feb 19, 2025 - Jun 26, 2025
#7-11.82%
Mar 29, 2018 - Apr 11, 2018		-13.02%
Jul 20, 2015 - Apr 18, 2016
#8-7.01%
Apr 18, 2018 - May 4, 2018		-10.10%
Jan 26, 2018 - Aug 6, 2018
#9-1.40%
Sep 24, 2018 - Sep 28, 2018		-9.44%
Sep 2, 2020 - Nov 11, 2020
#10-0.15%
Apr 12, 2018 - Apr 16, 2018		-9.30%
Jan 19, 2000 - Mar 17, 2000
#11N/A-9.05%
Jul 19, 2007 - Oct 5, 2007
#12N/A-8.88%
Jan 27, 2026 - Apr 14, 2026
#13N/A-8.41%
Jul 16, 2024 - Sep 19, 2024
#14N/A-7.35%
Sep 14, 2012 - Jan 2, 2013
#15N/A-7.27%
Sep 18, 2014 - Oct 31, 2014

Correlation

Correlation between QTTB and SPY is -0.79 which considered as a strong negative correlation - the stocks tend to move in opposite directions.

-0.79
-101

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