PTGX vs UEC

Comparison between Protagonist Therapeutics Inc (PTGX, Company) and Uranium Energy Corp (UEC, Company).

PTGX is from the Healthcare sector, while UEC is from the Energy sector.

5-Year PerformanceUEC has outperformed PTGX, delivering a return of +34.5% compared to +23.2%

PTGX vs UEC - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	PTGX(COMPANY)	UEC(COMPANY)
Market Cap	$6.56B	$6.58B
Max Drawdown	85.79%	97.40%
Sharpe Ratio	1.72	1.37
5Y Beta	0.24	1.59
Industry	Biotechnology	Uranium
P/E Ratio	-55.54	-75.12
Forward P/E	21.64	178.57
PEG Ratio	0.00	-5.46
5Y EPS CAGR	1.43%	20.67%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-1.80%	-1.85%
P/S Ratio	88.77	326.17
P/B Ratio	10.02	4.69

Market Cap

PTGX

$6.56B

Winner

UEC

$6.58B

Max Drawdown

Winner

PTGX

85.79%

UEC

97.40%

Sharpe Ratio

Winner

PTGX

1.72

UEC

1.37

5Y Beta

Winner

PTGX

0.24

UEC

1.59

Industry

PTGX

Biotechnology

UEC

Uranium

P/E Ratio

PTGX

-55.54

Winner

UEC

-75.12

Forward P/E

Winner

PTGX

21.64

UEC

178.57

PEG Ratio

PTGX

0.00

Winner

UEC

-5.46

5Y EPS CAGR

PTGX

1.43%

Winner

UEC

20.67%

Debt to Equity

PTGX

0.00%

UEC

0.00%

Free Cash Flow Yield

Winner

PTGX

-1.80%

UEC

-1.85%

P/S Ratio

Winner

PTGX

88.77

UEC

326.17

P/B Ratio

PTGX

10.02

Winner

UEC

4.69

PTGX vs UEC - Historical Returns

Returns include dividend reinvestment.

Period	PTGX	UEC
1 month	+1.06%	+2.68%
3 months	+5.65%	-12.07%
6 months	+10.62%	+12.22%
1 year	+109.25%	+129.12%
5 years(CAGR)	+23.17%	+34.47%
10 years(CAGR)	+24.43%	+33.45%
Max(CAGR)	+24.43%	+3.62%

PTGX

+1.06%

Winner

UEC

+2.68%

Winner

PTGX

+5.65%

UEC

-12.07%

PTGX

+10.62%

Winner

UEC

+12.22%

PTGX

+109.25%

Winner

UEC

+129.12%

5Y(CAGR)

PTGX

+23.17%

Winner

UEC

+34.47%

10Y(CAGR)

PTGX

+24.43%

Winner

UEC

+33.45%

Max(CAGR)

Winner

PTGX

+24.43%

UEC

+3.62%

PTGX vs UEC - Annual Returns (2007 - 2026)

Returns include dividend reinvestment.

Year	PTGX	UEC
2026	+14.20%	+5.03%
2025	+124.06%	+53.28%
2024	+64.82%	+3.88%
2023	+112.71%	+70.67%
2022	-69.11%	+4.86%
2021	+74.49%	+86.11%
2020	+190.91%	+90.25%
2019	+2.32%	-28.19%
2018	-68.18%	-34.21%
2017	-1.79%	+36.15%
2016	+87.95%	+0.90%
2015	N/A	-40.11%
2014	N/A	-6.91%
2013	N/A	-24.53%
2012	N/A	-16.07%
2011	N/A	-48.74%
2010	N/A	+58.53%
2009	N/A	+840.30%
2008	N/A	-90.77%
2007	N/A	-56.10%

PTGX vs UEC Drawdown Comparison

The maximum drawdown for PTGX was -85.79%, occurring on Jun 13, 2022. Recovery took 882 trading sessions.

The maximum drawdown for UEC was -97.40%, occurring on Dec 11, 2008. Recovery took 4221 trading sessions.

The current PTGX drawdown is -6.06%. The current UEC drawdown is -31.63%.

Rank	PTGX	UEC
#1	-85.79% Sep 1, 2021 - Mar 10, 2025	-97.40% Apr 9, 2007 - Jan 12, 2024
#2	-82.13% Dec 5, 2016 - Feb 16, 2021	-53.49% Nov 19, 2024 - Jul 24, 2025
#3	-31.58% Mar 11, 2025 - Aug 27, 2025	-48.05% Feb 1, 2024 - Oct 17, 2024
#4	-20.33% Oct 17, 2016 - Nov 10, 2016	-40.86% Jan 28, 2026 - May 19, 2026
#5	-19.04% Mar 19, 2021 - May 18, 2021	-34.89% Oct 15, 2025 - Jan 14, 2026
#6	-16.38% Dec 12, 2025 - Mar 9, 2026	-15.84% Oct 18, 2024 - Nov 19, 2024
#7	-15.52% Oct 10, 2025 - Nov 24, 2025	-12.49% Aug 15, 2025 - Sep 2, 2025
#8	-12.77% Feb 16, 2021 - Mar 2, 2021	-7.60% Jan 22, 2026 - Jan 28, 2026
#9	-11.53% Aug 19, 2016 - Aug 31, 2016	-7.50% Jan 16, 2024 - Feb 1, 2024
#10	-9.62% Jun 8, 2021 - Jun 11, 2021	-7.06% Sep 15, 2025 - Sep 22, 2025
#11	-8.53% Aug 27, 2025 - Sep 18, 2025	-6.48% Sep 29, 2025 - Oct 8, 2025
#12	-7.43% Mar 31, 2026 - Apr 15, 2026	-5.79% Sep 10, 2025 - Sep 15, 2025
#13	-7.20% Jun 14, 2021 - Jun 16, 2021	-4.81% Aug 8, 2025 - Aug 12, 2025
#14	-7.18% Apr 17, 2026 - May 1, 2026	-3.56% Jul 28, 2025 - Aug 4, 2025
#15	-6.02% Nov 26, 2025 - Dec 8, 2025	-3.21% Oct 8, 2025 - Oct 10, 2025