PTGX vs SNEX

Comparison between Protagonist Therapeutics Inc (PTGX, Company) and StoneX Group Inc (SNEX, Company).

PTGX is from the Healthcare sector, while SNEX is from the Financial Services sector.

5-Year PerformanceSNEX has outperformed PTGX, delivering a return of +41.4% compared to +23.1%

PTGX vs SNEX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	PTGX(COMPANY)	SNEX(COMPANY)
Market Cap	$8.54B	$8.54B
Max Drawdown	85.79%	97.89%
Sharpe Ratio	1.84	1.31
5Y Beta	0.27	1.09
Industry	Biotechnology	Capital Markets
P/E Ratio	-72.28	18.22
Forward P/E	28.74	9.79
PEG Ratio	N/A	0.41
5Y EPS CAGR	1.43%	15.65%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-1.38%	75.90%

Market Cap

PTGX

$8.54B

Winner

SNEX

$8.54B

Max Drawdown

Winner

PTGX

85.79%

SNEX

97.89%

Sharpe Ratio

Winner

PTGX

1.84

SNEX

1.31

5Y Beta

Winner

PTGX

0.27

SNEX

1.09

Industry

PTGX

Biotechnology

SNEX

Capital Markets

P/E Ratio

Winner

PTGX

-72.28

SNEX

18.22

Forward P/E

PTGX

28.74

Winner

SNEX

9.79

PEG Ratio

PTGX

N/A

SNEX

0.41

5Y EPS CAGR

PTGX

1.43%

Winner

SNEX

15.65%

Debt to Equity

PTGX

0.00%

SNEX

0.00%

Free Cash Flow Yield

PTGX

-1.38%

Winner

SNEX

75.90%

PTGX vs SNEX - Historical Returns

Returns include dividend reinvestment.

Period	PTGX	SNEX
1 month	+9.35%	-6.69%
3 months	+35.00%	+4.30%
6 months	+66.81%	+44.47%
1 year	+141.77%	+69.98%
5 years(CAGR)	+23.07%	+41.43%
10 years(CAGR)	+27.63%	+28.76%
Max(CAGR)	+27.63%	+17.24%

Winner

PTGX

+9.35%

SNEX

-6.69%

Winner

PTGX

+35.00%

SNEX

+4.30%

Winner

PTGX

+66.81%

SNEX

+44.47%

Winner

PTGX

+141.77%

SNEX

+69.98%

5Y(CAGR)

PTGX

+23.07%

Winner

SNEX

+41.43%

10Y(CAGR)

PTGX

+27.63%

Winner

SNEX

+28.76%

Max(CAGR)

Winner

PTGX

+27.63%

SNEX

+17.24%

PTGX vs SNEX - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	PTGX	SNEX
2026	+52.56%	+66.52%
2025	+124.06%	+42.40%
2024	+64.82%	+35.50%
2023	+112.71%	+16.09%
2022	-69.11%	+51.29%
2021	+74.49%	+5.29%
2020	+190.91%	+19.21%
2019	+2.32%	+32.69%
2018	-68.18%	-14.15%
2017	-1.79%	+5.25%
2016	+87.95%	+22.03%
2015	N/A	+65.40%
2014	N/A	+12.71%
2013	N/A	+1.33%
2012	N/A	-28.56%
2011	N/A	-1.67%
2010	N/A	+58.07%
2009	N/A	+67.90%
2008	N/A	-67.16%
2007	N/A	+5.22%
2006	N/A	+220.60%
2005	N/A	+22.97%
2004	N/A	+31.65%
2003	N/A	+212.58%
2002	N/A	+182.20%
2001	N/A	-79.33%
2000	N/A	-62.92%
1999	N/A	+48.19%

PTGX vs SNEX Drawdown Comparison

The maximum drawdown for PTGX was -85.79%, occurring on Jun 13, 2022. Recovery took 882 trading sessions.

The maximum drawdown for SNEX was -97.89%, occurring on Feb 13, 2002. Recovery took 1654 trading sessions.

The current PTGX drawdown is -5.61%. The current SNEX drawdown is -22.23%.

Rank	PTGX	SNEX
#1	-85.79% Sep 1, 2021 - Mar 10, 2025	-97.89% Jan 24, 2000 - Aug 22, 2006
#2	-82.13% Dec 5, 2016 - Feb 16, 2021	-86.86% Dec 20, 2006 - May 21, 2018
#3	-31.58% Mar 11, 2025 - Aug 27, 2025	-48.65% Aug 24, 2018 - Jun 8, 2020
#4	-20.33% Oct 17, 2016 - Nov 10, 2016	-30.89% Sep 5, 2006 - Oct 25, 2006
#5	-19.04% Mar 19, 2021 - May 18, 2021	-25.91% Jun 18, 2026 - Jul 17, 2026
#6	-16.38% Dec 12, 2025 - Mar 9, 2026	-24.80% Dec 9, 1999 - Dec 21, 1999
#7	-15.52% Oct 10, 2025 - Nov 24, 2025	-24.07% Mar 8, 2023 - Dec 21, 2023
#8	-12.77% Feb 16, 2021 - Mar 2, 2021	-21.99% Nov 3, 2021 - Feb 8, 2022
#9	-12.03% Apr 17, 2026 - Jun 11, 2026	-21.35% Dec 8, 2020 - Mar 12, 2021
#10	-11.53% Aug 19, 2016 - Aug 31, 2016	-20.91% Feb 26, 2026 - Apr 8, 2026
#11	-9.62% Jun 8, 2021 - Jun 11, 2021	-19.94% Sep 4, 2025 - Jan 15, 2026
#12	-8.53% Aug 27, 2025 - Sep 18, 2025	-19.12% Dec 27, 1999 - Jan 12, 2000
#13	-7.78% Jul 7, 2026 - Jul 17, 2026	-17.80% Dec 2, 2022 - Feb 10, 2023
#14	-7.43% Mar 31, 2026 - Apr 15, 2026	-17.74% Feb 20, 2025 - Apr 24, 2025
#15	-7.20% Jun 14, 2021 - Jun 16, 2021	-17.28% Jul 6, 2020 - Nov 10, 2020